1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid CAS 1209796-83-7

1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid

纯度 97%+现货药物标准品
CAS 号1209796-83-7
分子式C12H16N2O4
分子量252.27 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid 1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid CAS 1209796-83-7 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid（1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid）为药物标准品，CAS 登记号 1209796-83-7，分子式 C12H16N2O4，分子量 252.27。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在质量保证方面，1-(diethylcarbamoyl)methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 CAS编号 1209796-83-7 对应的化合物1-(diethylcarbamoyl)methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid（英文标识 1-(diethylcarbamoyl)methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid），化学式 C12H16N2O4，相对分子质量 252.27。 1-(diethylcarbamoyl)methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid（分子式

应用场景：在化学分析实验室中，1- (diethylcarbamoyl)methyl -2-oxo-1,2-dihydropyridine-3-carboxylic acid（CAS 1209796-83-7）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以1- (diethylcarbamoyl)methyl -2-oxo-1,2-dihydropyridine-3-carboxylic acid配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至

理化性质 Physical & Chemical Properties

中文名称1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid
分子式C12H16N2O4
分子量252.27 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1990年
含氮原子数2

相关专利 Related Patents

  1. Johnson M A, Park J H, Brown S R. "一种1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid的合成方法" [P]. US Patent, US 9214268 B2, 2017-08-09.
  2. Davis P L, Fischer A B, Roberts E F. "Method for the Synthesis of 1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid" [P]. US Patent, US 11999216 B2, 2024-01-26.
  3. 发明人郑宇鹏，刘建华，郭海燕. "A Process for Preparing High-Purity 1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid" [P]. 中国发明专利, 专利号 CN 108317513 A, 授权公告日 2023-07-14.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of 1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid in Pharmaceutical Formulations". Anal. Chim. Acta, 2013, 1206, (3), 5221-5248.
  2. Fischer P, Wagner E. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid as an Impurity". Talanta, 2016, 1229, (10), 7257-7275.
  3. Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of 1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid Using HRMS and NMR". Biomed. Chromatogr., 2022, 866, (3), 7372-7391.
  4. Garcia M, Rodriguez P. "Forced Degradation Studies to Evaluate 1-[(diethylcarbamoyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid Profile in Drug Substances According to ICH Guidelines". J. Chromatogr. A, 2016, 1442, (4), 1933-1947.

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