(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (人, bovine, dog, mouse,鼠) CAS 122018-58-0

(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat)

纯度 97%+现货药物标准品
CAS 号122018-58-0
分子式C72H104N20O17
分子量1521.74 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (人, bovine, dog, mouse,鼠) (Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat) CAS 122018-58-0 结构式 Chemical Structure

产品介绍 Description

(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (人, bovine, dog, mouse,鼠)（(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat)）是药物分析与质量控制领域常用的药物标准品，CAS 号 122018-58-0。分子式 C72H104N20O17，分子量 1521.74。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS, FID）。 化学式为 C72H104N20O17 的(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (人, bovine, dog, mouse,鼠)（(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat)），其CAS登记号是 122018-58-0，分子量为 1521.74 g/mol。 (Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (人, bovine, dog, mouse,鼠)（C72H104N20O17）含有含氮杂环结构，酰胺类，含羟基，含醚键。具有较强的吸湿性，羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。由于结构中存在

应用场景：从实际应用出发，(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (人, bovine, dog, mouse,鼠)（CAS 122018-58-0）在化学分析中作为关键的基准对照物质。 推荐以(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (人, bovine, dog, mouse,鼠)配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议

理化性质 Physical & Chemical Properties

中文名称(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (人, bovine, dog, mouse,鼠)
分子式C72H104N20O17
分子量1521.74 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）31.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1991年
含氮原子数20

相关专利 Related Patents

  1. 发明人高志强，胡光，罗永刚. "一种(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (人, bovine, dog, mouse,鼠)的合成方法" [P]. 中国发明专利, 专利号 CN 110563906 A, 授权公告日 2023-12-22.
  2. 发明人郑宇鹏，罗永刚，何建平. "Method for the Synthesis of (Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat)" [P]. 中国发明专利, 专利号 CN 109569585 B, 授权公告日 2021-04-10.
  3. 发明人徐明华，周伟，林芳. "A Process for Preparing High-Purity (Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat)" [P]. 中国发明专利, 专利号 CN 109651672 B, 授权公告日 2024-12-22.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of (Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (人, bovine, dog, mouse,鼠) in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2025, 2266, (10), 477-500.
  2. Jensen P, Larsen A M, Olsen K. "A Stability-Indicating HPLC Method for the Separation and Quantification of (Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (人, bovine, dog, mouse,鼠) as an Impurity". Sci. Total Environ., 2014, 1114, 5090-5120.
  3. O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of (Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat) Using HRMS and NMR". Environ. Sci. Technol., 2013, 287, 6929-6952.
  4. Fischer P, Wagner E. "Forced Degradation Studies to Evaluate (Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (人, bovine, dog, mouse,鼠) Profile in Drug Substances According to ICH Guidelines". J. Chromatogr. A, 2016, 388, (5), 6629-6639.

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