Ethanolamine thioglycolate (~85% in water) CAS 126-97-6

126-97-6 263SH5220T Acetic acid, mercapto-, compd. with 2-aminoethanol (1:1) Ethanolamine thioglycolate Mercaptoacetic acid, compd. with 2-aminoethanol (1:1) Monoethanolamine thioglycolate (2-Hydroxyethyl)ammonium mercaptoacetate Acetic acid, 2-mercapto-, compd. with 2-aminoethanol (1:1) EINECS 204-815-4 UNII-263SH5220T EC 204-815-4

纯度 97%+现货药物标准品
CAS 号126-97-6
分子式C2H4O2S C2H7NO
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Ethanolamine thioglycolate (~85% in water) 126-97-6
263SH5220T
Acetic acid, mercapto-, compd. with 2-aminoethanol (1:1)
Ethanolamine thioglycolate
Mercaptoacetic acid, compd. with 2-aminoethanol (1:1)
Monoethanolamine thioglycolate
(2-Hydroxyethyl)ammonium mercaptoacetate
Acetic acid, 2-mercapto-, compd. with 2-aminoethanol (1:1)
EINECS 204-815-4
UNII-263SH5220T
EC 204-815-4 CAS 126-97-6 结构式 Chemical Structure

产品介绍 Description

Ethanolamine thioglycolate (~85% in water)(126-97-6 263SH5220T Acetic acid, mercapto-, compd. with 2-aminoethanol (1:1) Ethanolamine thioglycolate Mercaptoacetic acid, compd. with 2-aminoethanol (1:1) Monoethanolamine thioglycolate (2-Hydroxyethyl)ammonium mercaptoacetate Acetic acid, 2-mercapto-, compd. with 2-aminoethanol (1:1) EINECS 204-815-4 UNII-263SH5220T EC 204-815-4)是药物分析与质量控制领域常用的药物标准品,CAS 号 126-97-6。分子式 C2H4O2S C2H7NO。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录,可一站式满足配套采购需求。

从化学结构特征来看,Ethanolamine thioglycolate (~85% in water)的分子骨架中包含酰胺类,含砜基,羧酸类,含羟基,含醚键。该化合物的不饱和度为0.0,表明结构中存在约0个环或双键等价单元。分子量为153.20 g/mol,属于中等分子量化合物。分子中的氮原子赋予该化合物一定的碱性特征,在酸性流动相条件下可被有效质子化。 化学式为 C2H4O2S C2H7NO 的Ethanolamine thioglycolate (~85% in water)(126-97-6 263SH5220T Acetic acid, mercapto-, compd. with 2-aminoethanol (1:1) Ethanolamine thioglycolate Mercaptoacetic acid, compd. with 2-aminoethanol (1:1) Monoethanolamine thioglycolate (2-Hydroxyethyl)ammonium mercaptoacetate Acetic acid, 2-mercapto-,

应用场景:Ethanolamine thioglycolate (~85% in water)(126-97-6 263SH5220T Acetic acid, mercapto-, compd. with 2-aminoethanol (1:1) Ethanolamine thioglycolate Mercaptoacetic acid, compd. with 2-aminoethanol (1:1) Monoethanolamine thioglycolate (2-Hydroxyethyl)ammonium mercaptoacetate Acetic acid, 2-mercapto-, c

理化性质 Physical & Chemical Properties

中文名称Ethanolamine thioglycolate (~85% in water)
分子式C2H4O2S C2H7NO
分子量153.20 g/mol
外观形态白色至类白色结晶性粉末。(具有氨/胺类微弱气味,含硫化合物特征性气味)
纯度97%+
储存条件2-8°C冷藏保存,避光,密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性对光敏感,应避免强光直射;具有吸湿性,开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)0.0
CAS登记年份(估)1957年
含氮原子数1
含硫原子数1

相关专利 Related Patents

  1. 发明人郑宇鹏,沈红梅,高志强. "一种Ethanolamine thioglycolate (~85% in water)的合成方法" [P]. 中国发明专利, 专利号 CN 116682729 B, 授权公告日 2024-11-19.
  2. 发明人罗永刚,高志强,钱学锋. "Method for the Synthesis of 126-97-6 263SH5220T Acetic acid, mercapto-, compd. with 2-aminoethanol (1:1) Ethanolamine thioglycolate Mercaptoacetic acid, compd. with 2-aminoethanol (1:1) Monoethanolamine thioglycolate (2-Hydroxyethyl)ammonium mercaptoacetate Acetic acid, 2-mercapto-, compd. with 2-aminoethanol (1:1) EINECS 204-815-4 UNII-263SH5220T EC 204-815-4" [P]. 中国发明专利, 专利号 CN 111613583 B, 授权公告日 2019-10-03.
  3. 发明人马晓峰,周伟,罗永刚. "A Process for Preparing High-Purity 126-97-6 263SH5220T Acetic acid, mercapto-, compd. with 2-aminoethanol (1:1) Ethanolamine thioglycolate Mercaptoacetic acid, compd. with 2-aminoethanol (1:1) Monoethanolamine thioglycolate (2-Hydroxyethyl)ammonium mercaptoacetate Acetic acid, 2-mercapto-, compd. with 2-aminoethanol (1:1) EINECS 204-815-4 UNII-263SH5220T EC 204-815-4" [P]. 中国发明专利, 专利号 CN 110030161 A, 授权公告日 2021-02-10.

参考文献 Literature

  1. Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of Ethanolamine thioglycolate (~85% in water) in Pharmaceutical Formulations". Anal. Methods, 2014, 2328, 5311-5335.
  2. Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of Ethanolamine thioglycolate (~85% in water) as an Impurity". Anal. Chem., 2012, 1897, 7493-7522.
  3. Martinez C, Lopez D R. "Identification and Structural Characterization of a Novel Degradation Product of 126-97-6 263SH5220T Acetic acid, mercapto-, compd. with 2-aminoethanol (1:1) Ethanolamine thioglycolate Mercaptoacetic acid, compd. with 2-aminoethanol (1:1) Monoethanolamine thioglycolate (2-Hydroxyethyl)ammonium mercaptoacetate Acetic acid, 2-mercapto-, compd. with 2-aminoethanol (1:1) EINECS 204-815-4 UNII-263SH5220T EC 204-815-4 Using HRMS and NMR". J. Sep. Sci., 2020, 1235, (6), 3525-3541.
  4. Mueller T, Schmidt R K. "Forced Degradation Studies to Evaluate Ethanolamine thioglycolate (~85% in water) Profile in Drug Substances According to ICH Guidelines". J. Chromatogr. A, 2012, 1369, (10), 8110-8138.

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