硫酸双氢链霉素 CAS 1425-61-2

1,1'-((1R,2R,3S,4R,5R,6S)-4-(((2R,3R,4R,5S)-3-(((2S,3S,4S,5R,6S)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-4-(hydroxymethyl)-5-methyltetrahydrofuran-2-yl)oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl)diguanidine xs

纯度 97%+现货药物标准品
CAS 号1425-61-2
分子式C21H41N7O12 H2O4S
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

硫酸双氢链霉素 1,1'-((1R,2R,3S,4R,5R,6S)-4-(((2R,3R,4R,5S)-3-(((2S,3S,4S,5R,6S)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-4-(hydroxymethyl)-5-methyltetrahydrofuran-2-yl)oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl)diguanidine xs CAS 1425-61-2 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的硫酸双氢链霉素（1,1'-((1R,2R,3S,4R,5R,6S)-4-(((2R,3R,4R,5S)-3-(((2S,3S,4S,5R,6S)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-4-(hydroxymethyl)-5-methyltetrahydrofuran-2-yl)oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl)diguanidine xs）为药物标准品，CAS 登记号 1425-61-2，分子式 C21H41N7O12 H2O4S。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括硫酸双氢链霉素在内的目标物的控制。 化学式为 C21H41N7O12 H2O4S 的硫酸双氢链霉素（1,1'-((1R,2R,3S,4R,5R,6S)-4-(((2R,3R,4R,5S)-3-(((2S,3S,4S,5R,6S)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-4-(hydroxymethyl)-5-methyltetrahydrofuran-2-yl)oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl)diguanidine xs），其CAS登记号是 1425-61-2，分子量为 681.67 g/mol。 依据分子式为 C21H41N7O12 H2O4S 的硫酸双氢链霉素结构特征，其分子内含含氮杂环结构，酰胺类，含砜基，含羟基，含醚键，这意味着该化合物在紫外光谱中会呈现特征性的吸收带。分子量 681.67 g/mol 这一参数对质谱检测中的分子离子

应用场景：硫酸双氢链霉素（1,1'-((1R,2R,3S,4R,5R,6S)-4-(((2R,3R,4R,5S)-3-(((2S,3S,4S,5R,6S)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-4-(hydroxymethyl)-5-methyltetrahydrofuran-2-yl)oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl)diguanidine xs，CAS 1425-61-2）的标准化应用场景涵盖化学分析等多个专业技术领

理化性质 Physical & Chemical Properties

中文名称硫酸双氢链霉素
分子式C21H41N7O12 H2O4S
分子量681.67 g/mol
外观形态类白色至淡黄色无定形粉末。（含硫化合物特征性气味）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1957年
含氮原子数7
含硫原子数1

相关专利 Related Patents

  1. 发明人杨光，李文辉，刘建华. "一种硫酸双氢链霉素的合成方法" [P]. 中国发明专利, 专利号 CN 110546285 B, 授权公告日 2015-10-27.
  2. 发明人郑宇鹏，周伟，韩伟. "Method for the Synthesis of 1,1'-((1R,2R,3S,4R,5R,6S)-4-(((2R,3R,4R,5S)-3-(((2S,3S,4S,5R,6S)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-4-(hydroxymethyl)-5-methyltetrahydrofuran-2-yl)oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl)diguanidine xs" [P]. 中国发明专利, 专利号 CN 117738190 B, 授权公告日 2025-01-10.
  3. 发明人朱建伟，胡光，张德明. "A Process for Preparing High-Purity 1,1'-((1R,2R,3S,4R,5R,6S)-4-(((2R,3R,4R,5S)-3-(((2S,3S,4S,5R,6S)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-4-(hydroxymethyl)-5-methyltetrahydrofuran-2-yl)oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl)diguanidine xs" [P]. 中国发明专利, 专利号 CN 116823522 A, 授权公告日 2025-05-17.

参考文献 Literature

  1. Brown R C, Davis S M. "Development and Validation of an LC-MS/MS Method for the Determination of 硫酸双氢链霉素 in Pharmaceutical Formulations". Anal. Chem., 2017, 2080, (7), 4175-4182.
  2. Hughes D, Roberts J, Thomas A. "A Stability-Indicating HPLC Method for the Separation and Quantification of 硫酸双氢链霉素 as an Impurity". J. Agric. Food Chem., 2011, 1534, (3), 2134-2152.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 1,1'-((1R,2R,3S,4R,5R,6S)-4-(((2R,3R,4R,5S)-3-(((2S,3S,4S,5R,6S)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-4-(hydroxymethyl)-5-methyltetrahydrofuran-2-yl)oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl)diguanidine xs Using HRMS and NMR". Phytochemistry, 2013, 2461, (2), 2973-3000.

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