CAS 16255-48-4

16255-48-4 DL2A9M9D6X Chloramphenicol stearate (R-(R*,R*))-2-((Dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl stearate Octadecanoic acid, 2-((dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl ester, (R-(R*,R*))- Stearic acid, alpha-ester with D-threo-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide Octadecanoic acid, (2R,3R)-2-((dichloroacetyl)amino)-3-hydrdoxy-3-(4-nitrophenyl)propyl ester 4-13-00-02754 (Beilstein Handbook Reference) BRN 2797487 Chloramphenicol monostearate Chloroamphenicol stearate Chloroamphenicol stearic acid ester 2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide alpha-stearate EINECS 240-363-4 Eusynthomycin Levomycetin stearate Madomicetina Stearic acid, ester with chloramphenicol UNII-DL2A9M9D6X

纯度 97%+现货药物标准品
CAS 号16255-48-4
分子式C29H46Cl2N2O6
分子量589.59 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

16255-48-4 DL2A9M9D6X Chloramphenicol stearate (R-(R*,R*))-2-((Dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl stearate Octadecanoic acid, 2-((dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl ester, (R-(R*,R*))- Stearic acid, alpha-ester with D-threo-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide Octadecanoic acid, (2R,3R)-2-((dichloroacetyl)amino)-3-hydrdoxy-3-(4-nitrophenyl)propyl ester 4-13-00-02754 (Beilstein Handbook Reference) BRN 2797487 Chloramphenicol monostearate Chloroamphenicol stearate Chloroamphenicol stearic acid ester 2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide alpha-stearate EINECS 240-363-4 Eusynthomycin Levomycetin stearate Madomicetina Stearic acid, ester with chloramphenicol UNII-DL2A9M9D6X CAS 16255-48-4 结构式 Chemical Structure

产品介绍 Description

（16255-48-4 DL2A9M9D6X Chloramphenicol stearate (R-(R*,R*))-2-((Dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl stearate Octadecanoic acid, 2-((dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl ester, (R-(R*,R*))- Stearic acid, alpha-ester with D-threo-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide Octadecanoic acid, (2R,3R)-2-((dichloroacetyl)amino)-3-hydrdoxy-3-(4-nitrophenyl)propyl ester 4-13-00-02754 (Beilstein Handbook Reference) BRN 2797487 Chloramphenicol monostearate Chloroamphenicol stearate Chloroamphenicol stearic acid ester 2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide alpha-stearate EINECS 240-363-4 Eusynthomycin Levomycetin stearate Madomicetina Stearic acid, ester with chloramphenicol UNII-DL2A9M9D6X）是药物分析与质量控制领域常用的药物标准品，CAS 号 16255-48-4。分子式 C29H46Cl2N2O6，分子量 589.59。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

从化学结构特征来看，的分子骨架中包含甾体骨架，酰胺类，含羟基，含醚键，含氯取代。该化合物的不饱和度为7.0，表明结构中存在约7个环或双键等价单元。分子量为589.59 g/mol，属于较高分子量化合物。分子中包含芳环或共轭体系，在UV-Vis光谱中具有特征性吸收带，适用于紫外或二极管阵列检测器（DAD）的定量分析。 化学式为 C29H46Cl2N2O6 的（16255-48-4 DL2A9M9D6X Chloramphenicol stearate (R-(R,R))-2-((Dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl stearate Octadecanoic acid, 2-((dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl ester, (R-(R,R))- Stearic acid, alpha-ester with D-threo-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl

应用场景：从实际应用出发，（CAS 16255-48-4）在化学分析中作为关键的基准对照物质。 推荐以配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇/乙腈（1:1）配制，于阴凉处（≤25°C）保存，避光，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称
分子式C29H46Cl2N2O6
分子量589.59 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1961年
卤素含量Cl取代
含氮原子数2

相关专利 Related Patents

  1. 发明人韩伟，郑宇鹏，赵玉洁. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 115896368 A, 授权公告日 2023-12-12.
  2. Schröder R, Björnsson E, Sørensen M. "Method for the Synthesis of 16255-48-4 DL2A9M9D6X Chloramphenicol stearate (R-(R*,R*))-2-((Dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl stearate Octadecanoic acid, 2-((dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl ester, (R-(R*,R*))- Stearic acid, alpha-ester with D-threo-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide Octadecanoic acid, (2R,3R)-2-((dichloroacetyl)amino)-3-hydrdoxy-3-(4-nitrophenyl)propyl ester 4-13-00-02754 (Beilstein Handbook Reference) BRN 2797487 Chloramphenicol monostearate Chloroamphenicol stearate Chloroamphenicol stearic acid ester 2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide alpha-stearate EINECS 240-363-4 Eusynthomycin Levomycetin stearate Madomicetina Stearic acid, ester with chloramphenicol UNII-DL2A9M9D6X" [P]. European Patent, EP 3154664 A1, 2021-06-12.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Molecules, 2018, 2038, 1173-1182.
  2. Garcia M, Rodriguez P. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Biomed. Chromatogr., 2011, 1203, (1), 573-595.
  3. Zhou X P, Huang L, Wu G. "Identification and Structural Characterization of a Novel Degradation Product of 16255-48-4 DL2A9M9D6X Chloramphenicol stearate (R-(R*,R*))-2-((Dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl stearate Octadecanoic acid, 2-((dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl ester, (R-(R*,R*))- Stearic acid, alpha-ester with D-threo-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide Octadecanoic acid, (2R,3R)-2-((dichloroacetyl)amino)-3-hydrdoxy-3-(4-nitrophenyl)propyl ester 4-13-00-02754 (Beilstein Handbook Reference) BRN 2797487 Chloramphenicol monostearate Chloroamphenicol stearate Chloroamphenicol stearic acid ester 2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide alpha-stearate EINECS 240-363-4 Eusynthomycin Levomycetin stearate Madomicetina Stearic acid, ester with chloramphenicol UNII-DL2A9M9D6X Using HRMS and NMR". Anal. Chem., 2015, 88, 7560-7590.

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