3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride CAS 164648-33-3

3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride

纯度 97%+现货药物标准品
CAS 号164648-33-3
分子式C13H17N3O2 HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride 3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride CAS 164648-33-3 结构式 Chemical Structure

产品介绍 Description

3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride（3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride）是药物分析与质量控制领域常用的药物标准品，CAS 号 164648-33-3。分子式 C13H17N3O2 HCl。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

作为认证标准物质（CRM），3-4-(aminomethyl)benzyl-5,5-dimethylimidazolidine-2,4-dione hydrochloride满足CNAS-CL04（ISO/IEC 17025）对标准物质的计量溯源性要求。批间一致性通过控制图（Control Chart）进行持续监控，保证不同批次间量值的一致性。 3-4-(aminomethyl)benzyl-5,5-dimethylimidazolidine-2,4-dione hydrochloride（3-4-(aminomethyl)benzyl-5,5-dimethylimidazolidine-2,4-dione hydrochloride），CAS注册编号 164648-33-3，化学分子式为 C13H17N3O2 HCl，分子量 283.76 g/mol。 从化学结构特征来看，3-4-(aminomethyl)benzyl-5,5-dimethylimidazolidine-2,4-dione hydrochloride的分子骨架中包含含氮杂环结构，酰

应用场景：从实际应用出发，3- 4-(aminomethyl)benzyl -5,5-dimethylimidazolidine-2,4-dione hydrochloride（CAS 164648-33-3）在化学分析中作为关键的基准对照物质。 推荐以3- 4-(aminomethyl)benzyl -5,5-dimethylimidazolidine-2,4-dione hydrochloride配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟

理化性质 Physical & Chemical Properties

中文名称3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride
分子式C13H17N3O2 HCl
分子量283.76 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2004年
卤素含量Cl取代
含氮原子数3

相关专利 Related Patents

  1. Rossi M, Schröder R, Johansson L. "一种3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride的合成方法" [P]. European Patent, EP 3911612 A1, 2023-07-21.
  2. 发明人张德明，钱学锋，黄志刚. "Method for the Synthesis of 3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride" [P]. 中国发明专利, 专利号 CN 111823406 A, 授权公告日 2023-08-03.

参考文献 Literature

  1. Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of 3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2020, 469, 3301-3314.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride as an Impurity". J. Chromatogr. A, 2015, 2459, 8671-8692.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of 3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride Using HRMS and NMR". Environ. Sci. Technol., 2011, 1296, (1), 5445-5474.
  4. Chen X Y, Liu M, Zhao W Q. "Forced Degradation Studies to Evaluate 3-[4-(aminomethyl)benzyl]-5,5-dimethylimidazolidine-2,4-dione hydrochloride Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2022, 1978, (12), 5185-5197.

Related aminomethyl Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...