CAS 174286-23-8

(2S,3S,4S,5R,6S)-4-(((2S,3R,4S,5S,6R)-3-Acetoxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-((5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-3-yl)oxy)-2-methyltetrahydro-2H-pyran-3-yl acetate

纯度 97%+现货药物标准品
CAS 号174286-23-8
分子式C43H54O22
分子量922.88 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(2S,3S,4S,5R,6S)-4-(((2S,3R,4S,5S,6R)-3-Acetoxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-((5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-3-yl)oxy)-2-methyltetrahydro-2H-pyran-3-yl acetate CAS 174286-23-8 结构式 Chemical Structure

产品介绍 Description

CAS 174286-23-8 对应的（(2S,3S,4S,5R,6S)-4-(((2S,3R,4S,5S,6R)-3-Acetoxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-((5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-3-yl)oxy)-2-methyltetrahydro-2H-pyran-3-yl acetate）为 CATO 佳途药物标准品产品线成员。分子式 C43H54O22，分子量 922.88。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

（C43H54O22）含有羧酸类，含羟基，含醚键，多环芳烃。羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。由于结构中存在共轭发色团，该化合物在200-400 nm区间具有显著的紫外吸收，便于HPLC-UV检测。 化学式为 C43H54O22 的（(2S,3S,4S,5R,6S)-4-(((2S,3R,4S,5S,6R)-3-Acetoxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-((5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-3-yl)oxy)-2-methyltetrahydro-2H-pyran-3-yl acetate），其CAS登记号是 174286-23-8，分

应用场景：（(2S,3S,4S,5R,6S)-4-(((2S,3R,4S,5S,6R)-3-Acetoxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-((5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-3-yl)oxy)-2-methyl

理化性质 Physical & Chemical Properties

中文名称
分子式C43H54O22
分子量922.88 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）17.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2006年

相关专利 Related Patents

  1. 发明人李文辉，高志强，周伟. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 109950888 A, 授权公告日 2015-06-10.
  2. 发明人王建平，唐晓军，马晓峰. "Method for the Synthesis of (2S,3S,4S,5R,6S)-4-(((2S,3R,4S,5S,6R)-3-Acetoxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-((5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-3-yl)oxy)-2-methyltetrahydro-2H-pyran-3-yl acetate" [P]. 中国发明专利, 专利号 CN 108897421 A, 授权公告日 2019-11-09.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Anal. Chem., 2023, 2327, (12), 8523-8529.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Anal. Methods, 2012, 2064, 2087-2109.
  3. Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of (2S,3S,4S,5R,6S)-4-(((2S,3R,4S,5S,6R)-3-Acetoxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-((5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-3-yl)oxy)-2-methyltetrahydro-2H-pyran-3-yl acetate Using HRMS and NMR". J. Agric. Food Chem., 2023, 2432, 2899-2916.
  4. Kim S H, Park J Y. "Forced Degradation Studies to Evaluate Profile in Drug Substances According to ICH Guidelines". Chromatographia, 2011, 1018, 4274-4279.

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