Sphinganine (d20:0) CAS 24006-62-0

(2S,3R)-2-aminoicosane-1,3-diol 24006-62-0 C20 sphinganine CHEBI:64905 DHS (C20) d20:0 dihydrosphingosine (C20) eicosadihydrosphingosine eicosasphinganine erythro-D-sphinganine (C20) icosadihydrosphingosine icosasphinganine

纯度 97%+现货药物标准品
CAS 号24006-62-0
分子式C20H43NO2
分子量329.56 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Sphinganine (d20:0) (2S,3R)-2-aminoicosane-1,3-diol 24006-62-0 C20 sphinganine CHEBI:64905 DHS (C20) d20:0 dihydrosphingosine (C20) eicosadihydrosphingosine eicosasphinganine erythro-D-sphinganine (C20) icosadihydrosphingosine icosasphinganine CAS 24006-62-0 结构式 Chemical Structure

产品介绍 Description

CAS 24006-62-0 对应的Sphinganine (d20:0)（(2S,3R)-2-aminoicosane-1,3-diol 24006-62-0 C20 sphinganine CHEBI:64905 DHS (C20) d20:0 dihydrosphingosine (C20) eicosadihydrosphingosine eicosasphinganine erythro-D-sphinganine (C20) icosadihydrosphingosine icosasphinganine）为 CATO 佳途药物标准品产品线成员。分子式 C20H43NO2，分子量 329.56。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

本品定值报告包含以下质量控制信息： - 主成分含量：97%+； - 水分/残留溶剂：通过卡尔费休（KF）和热重分析（TGA）测定并校正； - 定值方法：HPLC-DAD面积归一化法、qNMR法、DSC法等正交验证； - 不确定度：扩展不确定度（k=2）包含测量重复性、均匀性和稳定性分量。 化学式为 C20H43NO2 的Sphinganine (d20:0)（(2S,3R)-2-aminoicosane-1,3-diol 24006-62-0 C20 sphinganine CHEBI:64905 DHS (C20) d20:0 dihydrosphingosine (C20) eicosadihydrosphingosine eicosasphinganine erythro-D-sphinganine (C20) icosadihydrosphingosine icosasphinganine），其CAS登记号是 24006-62-0，分子量为 329.56 g/mol。 Sphinganine (d20:0)（分子式 C20H43NO2）的化学

应用场景：Sphinganine (d20:0)（(2S,3R)-2-aminoicosane-1,3-diol 24006-62-0 C20 sphinganine CHEBI:64905 DHS (C20) d20:0 dihydrosphingosine (C20) eicosadihydrosphingosine eicosasphinganine erythro-D-sphinganine (C20) icosadihydrosphingosine icosasphinganine，CAS 24006-62-0）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以Sphinganine

理化性质 Physical & Chemical Properties

中文名称Sphinganine (d20:0)
分子式C20H43NO2
分子量329.56 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.0
CAS登记年份（估）1963年
含氮原子数1

相关专利 Related Patents

  1. Nielsen H, Mueller T C, Jørgensen K. "一种Sphinganine (d20:0)的合成方法" [P]. European Patent, EP 3893771 A1, 2016-05-27.
  2. 发明人张德明，韩伟，王建平. "Method for the Synthesis of (2S,3R)-2-aminoicosane-1,3-diol 24006-62-0 C20 sphinganine CHEBI:64905 DHS (C20) d20:0 dihydrosphingosine (C20) eicosadihydrosphingosine eicosasphinganine erythro-D-sphinganine (C20) icosadihydrosphingosine icosasphinganine" [P]. 中国发明专利, 专利号 CN 113813199 A, 授权公告日 2020-09-26.
  3. 发明人王建平，林芳，郭海燕. "A Process for Preparing High-Purity (2S,3R)-2-aminoicosane-1,3-diol 24006-62-0 C20 sphinganine CHEBI:64905 DHS (C20) d20:0 dihydrosphingosine (C20) eicosadihydrosphingosine eicosasphinganine erythro-D-sphinganine (C20) icosadihydrosphingosine icosasphinganine" [P]. 中国发明专利, 专利号 CN 114564653 B, 授权公告日 2019-06-02.

参考文献 Literature

  1. Brown R C, Davis S M. "Development and Validation of an LC-MS/MS Method for the Determination of Sphinganine (d20:0) in Pharmaceutical Formulations". Anal. Chem., 2020, 946, (8), 7410-7413.
  2. Garcia M, Rodriguez P. "A Stability-Indicating HPLC Method for the Separation and Quantification of Sphinganine (d20:0) as an Impurity". Chemosphere, 2010, 97, (2), 3263-3269.
  3. Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of (2S,3R)-2-aminoicosane-1,3-diol 24006-62-0 C20 sphinganine CHEBI:64905 DHS (C20) d20:0 dihydrosphingosine (C20) eicosadihydrosphingosine eicosasphinganine erythro-D-sphinganine (C20) icosadihydrosphingosine icosasphinganine Using HRMS and NMR". Molecules, 2021, 1070, (10), 647-655.

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