<I></I>邻甲酚酞络合酮 CAS 2411-89-4

(1/2)ethEoI feminine 2411-89-4 AU(1/4)x.OI feminine-3 inverted exclamation marka,3 inverted exclamation marka inverted exclamation marka-E<<(1/4)x>>uNC degrees +/->>u paragraph signthornOOEa AU(1/4)x.OI feminineAc masculineI(1/4)A I femininexI METALPHTHALEIN I Metal phthalein Phthalein purple Xylenylphthalein-bisiminodiacetic acid [({5-[1-(3-{[bis(carboxymethyl)amino]methyl}-4-hydroxy-5-methylphenyl)-3-oxo-2-benzofuran-1-yl]-2-hydroxy-3-methylphenyl}methyl)(carboxymethyl)amino]acetic acid o-Cresolphthalein-3',3''-bis-methyleneiminodiacetic acid o-Cresolphthalexon paragraph signthorn(1/4)x+/-(1/2)I feminine-E<<NC degrees +/->>u paragraph signthornOOEa

纯度 97%+现货药物标准品
CAS 号2411-89-4
分子式C32H50N2O12
分子量654.75 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

<I></I>邻甲酚酞络合酮 (1/2)ethEoI feminine 2411-89-4 AU(1/4)x.OI feminine-3 inverted exclamation marka,3 inverted exclamation marka inverted exclamation marka-E<<(1/4)x>>uNC degrees +/->>u paragraph signthornOOEa AU(1/4)x.OI feminineAc masculineI(1/4)A I femininexI METALPHTHALEIN I Metal phthalein Phthalein purple Xylenylphthalein-bisiminodiacetic acid [({5-[1-(3-{[bis(carboxymethyl)amino]methyl}-4-hydroxy-5-methylphenyl)-3-oxo-2-benzofuran-1-yl]-2-hydroxy-3-methylphenyl}methyl)(carboxymethyl)amino]acetic acid o-Cresolphthalein-3',3''-bis-methyleneiminodiacetic acid o-Cresolphthalexon paragraph signthorn(1/4)x+/-(1/2)I feminine-E<<NC degrees +/->>u paragraph signthornOOEa CAS 2411-89-4 结构式 Chemical Structure

产品介绍 Description

<I></I>邻甲酚酞络合酮（(1/2)ethEoI feminine 2411-89-4 AU(1/4)x.OI feminine-3 inverted exclamation marka,3 inverted exclamation marka inverted exclamation marka-E<<(1/4)x>>uNC degrees +/->>u paragraph signthornOOEa AU(1/4)x.OI feminineAc masculineI(1/4)A I femininexI METALPHTHALEIN I Metal phthalein Phthalein purple Xylenylphthalein-bisiminodiacetic acid [({5-[1-(3-{[bis(carboxymethyl)amino]methyl}-4-hydroxy-5-methylphenyl)-3-oxo-2-benzofuran-1-yl]-2-hydroxy-3-methylphenyl}methyl)(carboxymethyl)amino]acetic acid o-Cresolphthalein-3',3''-bis-methyleneiminodiacetic acid o-Cresolphthalexon paragraph signthorn(1/4)x+/-(1/2)I feminine-E<<NC degrees +/->>u paragraph signthornOOEa，CAS 号 2411-89-4）是 CATO 佳途自主生产的药物标准品，分子式 C32H50N2O12，分子量 654.75。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

<I></I>邻甲酚酞络合酮的产生途径与其化学式中含氮杂环结构，酰胺类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 <I></I>邻甲酚酞络合酮（(1/2)ethEoI feminine 2411-89-4 AU(1/4)x.OI feminine-3 inverted exclamation marka,3 inverted exclamation marka inverted exclamation marka-E<<(1/4)x>>uNC degrees +/->>u paragraph signthornOOEa AU(1/4)x.OI feminineAc masculineI(1/4)A I femininexI METALPHTHALEIN I Metal phthalein Phthalein purple Xylenylphthalein-bisiminodiacetic acid ({5-1-(3-{bis(carboxymethyl)aminomethyl}-4-hydroxy-5-methylphenyl)-3

应用场景：针对化学分析用途，<I></I>邻甲酚酞络合酮（(1/2)ethEoI feminine 2411-89-4 AU(1/4)x.OI feminine-3 inverted exclamation marka,3 inverted exclamation marka inverted exclamation marka-E<<(1/4)x>>uNC degrees +/->>u paragraph signthornOOEa AU(1/4)x.OI feminineAc masculineI(1/4)A I femininexI METALPHTHALEIN I Metal phthalein

理化性质 Physical & Chemical Properties

中文名称<I></I>邻甲酚酞络合酮
分子式C32H50N2O12
分子量654.75 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）9.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1957年
含氮原子数2

相关专利 Related Patents

  1. 发明人钱学锋，唐晓军，高志强. "一种<I></I>邻甲酚酞络合酮的合成方法" [P]. 中国发明专利, 专利号 CN 111950752 B, 授权公告日 2023-06-26.
  2. 发明人郭海燕，杨光，唐晓军. "Method for the Synthesis of (1/2)ethEoI feminine 2411-89-4 AU(1/4)x.OI feminine-3 inverted exclamation marka,3 inverted exclamation marka inverted exclamation marka-E<<(1/4)x>>uNC degrees +/->>u paragraph signthornOOEa AU(1/4)x.OI feminineAc masculineI(1/4)A I femininexI METALPHTHALEIN I Metal phthalein Phthalein purple Xylenylphthalein-bisiminodiacetic acid [({5-[1-(3-{[bis(carboxymethyl)amino]methyl}-4-hydroxy-5-methylphenyl)-3-oxo-2-benzofuran-1-yl]-2-hydroxy-3-methylphenyl}methyl)(carboxymethyl)amino]acetic acid o-Cresolphthalein-3',3''-bis-methyleneiminodiacetic acid o-Cresolphthalexon paragraph signthorn(1/4)x+/-(1/2)I feminine-E<<NC degrees +/->>u paragraph signthornOOEa" [P]. 中国发明专利, 专利号 CN 108469592 A, 授权公告日 2017-02-04.
  3. 发明人黄志刚，孙丽萍，马晓峰. "A Process for Preparing High-Purity (1/2)ethEoI feminine 2411-89-4 AU(1/4)x.OI feminine-3 inverted exclamation marka,3 inverted exclamation marka inverted exclamation marka-E<<(1/4)x>>uNC degrees +/->>u paragraph signthornOOEa AU(1/4)x.OI feminineAc masculineI(1/4)A I femininexI METALPHTHALEIN I Metal phthalein Phthalein purple Xylenylphthalein-bisiminodiacetic acid [({5-[1-(3-{[bis(carboxymethyl)amino]methyl}-4-hydroxy-5-methylphenyl)-3-oxo-2-benzofuran-1-yl]-2-hydroxy-3-methylphenyl}methyl)(carboxymethyl)amino]acetic acid o-Cresolphthalein-3',3''-bis-methyleneiminodiacetic acid o-Cresolphthalexon paragraph signthorn(1/4)x+/-(1/2)I feminine-E<<NC degrees +/->>u paragraph signthornOOEa" [P]. 中国发明专利, 专利号 CN 111272935 B, 授权公告日 2016-09-01.

参考文献 Literature

  1. Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of <I></I>邻甲酚酞络合酮 in Pharmaceutical Formulations". J. Agric. Food Chem., 2018, 2304, (6), 2483-2509.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of <I></I>邻甲酚酞络合酮 as an Impurity". J. Sep. Sci., 2018, 1734, 11-32.
  3. Zhang Y, Li Q, Chen T. "Identification and Structural Characterization of a Novel Degradation Product of (1/2)ethEoI feminine 2411-89-4 AU(1/4)x.OI feminine-3 inverted exclamation marka,3 inverted exclamation marka inverted exclamation marka-E<<(1/4)x>>uNC degrees +/->>u paragraph signthornOOEa AU(1/4)x.OI feminineAc masculineI(1/4)A I femininexI METALPHTHALEIN I Metal phthalein Phthalein purple Xylenylphthalein-bisiminodiacetic acid [({5-[1-(3-{[bis(carboxymethyl)amino]methyl}-4-hydroxy-5-methylphenyl)-3-oxo-2-benzofuran-1-yl]-2-hydroxy-3-methylphenyl}methyl)(carboxymethyl)amino]acetic acid o-Cresolphthalein-3',3''-bis-methyleneiminodiacetic acid o-Cresolphthalexon paragraph signthorn(1/4)x+/-(1/2)I feminine-E<<NC degrees +/->>u paragraph signthornOOEa Using HRMS and NMR". Rapid Commun. Mass Spectrom., 2014, 1477, 2770-2783.
  4. Martinez C, Lopez D R. "Forced Degradation Studies to Evaluate <I></I>邻甲酚酞络合酮 Profile in Drug Substances According to ICH Guidelines". J. Pharm. Biomed. Anal., 2014, 1896, (4), 8406-8433.

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