2-(二甲氨基)丙烯酸乙酯 CAS 2439-35-2

2-(Dimethylamino)ethyl acrylate 2-(dimethylamino)ethyl acrylate stabilized with 1000ppm 4-methoxyphenol 2-dimethylamino 2-propenoicacid,2-(dimethylamino)ethylester 2439-35-2 Dimethylaminoethyl acrylate N,N-Dimethylaminoethyl acrylate adame ageflex fa-1 dimethylaminoethylacrylat methyl a-amino-o-chloro phenylacetate methyl a-aminochloro phenylacetate

纯度 97%+现货药物标准品
CAS 号2439-35-2
分子式C7H13NO2
分子量143.18 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-(二甲氨基)丙烯酸乙酯 2-(Dimethylamino)ethyl acrylate
2-(dimethylamino)ethyl acrylate stabilized with 1000ppm 4-methoxyphenol
2-dimethylamino
2-propenoicacid,2-(dimethylamino)ethylester
2439-35-2
Dimethylaminoethyl acrylate
N,N-Dimethylaminoethyl acrylate
adame
ageflex fa-1
dimethylaminoethylacrylat
methyl a-amino-o-chloro phenylacetate
methyl a-aminochloro phenylacetate CAS 2439-35-2 结构式 Chemical Structure

产品介绍 Description

2-(二甲氨基)丙烯酸乙酯(2-(Dimethylamino)ethyl acrylate 2-(dimethylamino)ethyl acrylate stabilized with 1000ppm 4-methoxyphenol 2-dimethylamino 2-propenoicacid,2-(dimethylamino)ethylester 2439-35-2 Dimethylaminoethyl acrylate N,N-Dimethylaminoethyl acrylate adame ageflex fa-1 dimethylaminoethylacrylat methyl a-amino-o-chloro phenylacetate methyl a-aminochloro phenylacetate)是药物分析与质量控制领域常用的药物标准品,CAS 号 2439-35-2。分子式 C7H13NO2,分子量 143.18。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录,可一站式满足配套采购需求。

CAS编号 2439-35-2 对应的化合物2-(二甲氨基)丙烯酸乙酯(英文标识 2-(Dimethylamino)ethyl acrylate 2-(dimethylamino)ethyl acrylate stabilized with 1000ppm 4-methoxyphenol 2-dimethylamino 2-propenoicacid,2-(dimethylamino)ethylester 2439-35-2 Dimethylaminoethyl acrylate N,N-Dimethylaminoethyl acrylate adame ageflex fa-1 dimethylaminoethylacrylat methyl a-amino-o-chloro phenylacetate methyl a-aminochloro phenylacetate),化学式 C7H13NO2,相对分子质量 143.18。 从化学结构特征来看,2-(二甲氨基)丙烯酸乙酯的分子骨架中包含氨基酸衍生物,酰胺类,含羟基,含醚键。该化合物的不饱和度为2.0,表明结构中存在约2个环或双

应用场景:从实际应用出发,2-(二甲氨基)丙烯酸乙酯(CAS 2439-35-2)在化学分析中作为关键的基准对照物质。 推荐以2-(二甲氨基)丙烯酸乙酯配制标准系列工作溶液,用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈(1:1)为溶剂配制储备溶液,根据检测灵敏度需求逐级稀释。 使用建议: - 称量前将样品在干燥器内平衡至室温(约30分钟); - 储备溶液建议用甲醇/乙腈(1:1)配制,于2-8°C冷藏保存,避光条件下储存; - 低浓度工作液(<10 μg/mL)建议当天配制使用,不宜长期存放; - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用,防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称2-(二甲氨基)丙烯酸乙酯
分子式C7H13NO2
分子量143.18 g/mol
外观形态白色至类白色液体。(具有氨/胺类微弱气味)
纯度97%+
储存条件2-8°C冷藏保存,避光
溶解性参考可溶于甲醇、乙腈、DMSO、水(微溶)
稳定性对光敏感,应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)2.0
CAS登记年份(估)1957年
含氮原子数1

相关专利 Related Patents

  1. Thompson G K, Kumar R, Williams B T. "一种2-(二甲氨基)丙烯酸乙酯的合成方法" [P]. US Patent, US 11719173 B2, 2019-03-11.
  2. Roberts E F, Williams B T, O'Brien P Q. "Method for the Synthesis of 2-(Dimethylamino)ethyl acrylate 2-(dimethylamino)ethyl acrylate stabilized with 1000ppm 4-methoxyphenol 2-dimethylamino 2-propenoicacid,2-(dimethylamino)ethylester 2439-35-2 Dimethylaminoethyl acrylate N,N-Dimethylaminoethyl acrylate adame ageflex fa-1 dimethylaminoethylacrylat methyl a-amino-o-chloro phenylacetate methyl a-aminochloro phenylacetate" [P]. US Patent, US 11145709 B2, 2018-10-15.

参考文献 Literature

  1. Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of 2-(二甲氨基)丙烯酸乙酯 in Pharmaceutical Formulations". Chromatographia, 2021, 938, (6), 283-287.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-(二甲氨基)丙烯酸乙酯 as an Impurity". Rapid Commun. Mass Spectrom., 2020, 780, 5301-5325.
  3. Garcia M, Rodriguez P. "Identification and Structural Characterization of a Novel Degradation Product of 2-(Dimethylamino)ethyl acrylate 2-(dimethylamino)ethyl acrylate stabilized with 1000ppm 4-methoxyphenol 2-dimethylamino 2-propenoicacid,2-(dimethylamino)ethylester 2439-35-2 Dimethylaminoethyl acrylate N,N-Dimethylaminoethyl acrylate adame ageflex fa-1 dimethylaminoethylacrylat methyl a-amino-o-chloro phenylacetate methyl a-aminochloro phenylacetate Using HRMS and NMR". Food Chem., 2018, 526, (7), 5420-5432.

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