4-溴-2,6-二甲基苯胺 CAS 24596-19-8
24596-19-8 4-BROMO-2,6-DIMETHYL-BENZENAMINE 4-BROMO-2,6-DIMETHYL-PHENYLAMINE 4-BROMO-2,6-XYLIDINE 4-Bromo-2,6-dimethylaniline AS00438 BENZENAMINE, 4-BROMO-2,6-DIMETHYL- LABOTEST-BB LT01143222 LABOTEST-BB LT03329516 LABOTEST-BB LT03331441 TIMTEC-BB SBB002410
| CAS 号 | 24596-19-8 |
| 分子式 | C8H16BrN |
| 分子量 | 206.12 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
4-溴-2,6-二甲基苯胺（24596-19-8 4-BROMO-2,6-DIMETHYL-BENZENAMINE 4-BROMO-2,6-DIMETHYL-PHENYLAMINE 4-BROMO-2,6-XYLIDINE 4-Bromo-2,6-dimethylaniline AS00438 BENZENAMINE, 4-BROMO-2,6-DIMETHYL- LABOTEST-BB LT01143222 LABOTEST-BB LT03329516 LABOTEST-BB LT03331441 TIMTEC-BB SBB002410，CAS 号 24596-19-8）是 CATO 佳途自主生产的药物标准品，分子式 C8H16BrN，分子量 206.12。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。
4-溴-2,6-二甲基苯胺（24596-19-8 4-BROMO-2,6-DIMETHYL-BENZENAMINE 4-BROMO-2,6-DIMETHYL-PHENYLAMINE 4-BROMO-2,6-XYLIDINE 4-Bromo-2,6-dimethylaniline AS00438 BENZENAMINE, 4-BROMO-2,6-DIMETHYL- LABOTEST-BB LT01143222 LABOTEST-BB LT03329516 LABOTEST-BB LT03331441 TIMTEC-BB SBB002410），CAS注册编号 24596-19-8，化学分子式为 C8H16BrN，分子量 206.12 g/mol。 受分子结构中含溴取代的影响，4-溴-2,6-二甲基苯胺表现为白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）。其固体形态的物理化学属性——包括206.12 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。卤素原子的引入增加了化合物的电负性，在ECD（电子捕获检测器）中具有优良的响应灵敏度。 在
应用场景：4-溴-2,6-二甲基苯胺（24596-19-8 4-BROMO-2,6-DIMETHYL-BENZENAMINE 4-BROMO-2,6-DIMETHYL-PHENYLAMINE 4-BROMO-2,6-XYLIDINE 4-Bromo-2,6-dimethylaniline AS00438 BENZENAMINE, 4-BROMO-2,6-DIMETHYL- LABOTEST-BB LT01143222 LABOTEST-BB LT03329516 LABOTEST-BB LT03331441 TIMTEC-BB SBB002410，CAS 24596-19-8）的标准化应用场景涵盖化学分
理化性质 Physical & Chemical Properties
| 中文名称 | 4-溴-2,6-二甲基苯胺 |
| 分子式 | C8H16BrN |
| 分子量 | 206.12 g/mol |
| 外观形态 | 白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味） |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光，密闭保存防止挥发 |
| 溶解性参考 | 可溶于甲醇、乙腈、DMSO |
| 稳定性 | 对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 1.0 |
| CAS登记年份（估） | 1964年 |
| 卤素含量 | Br取代 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人唐晓军，韩伟，周伟. "一种4-溴-2,6-二甲基苯胺的合成方法" [P]. 中国发明专利, 专利号 CN 114865808 B, 授权公告日 2023-06-06.
- 发明人韩伟，李文辉，高志强. "Method for the Synthesis of 24596-19-8 4-BROMO-2,6-DIMETHYL-BENZENAMINE 4-BROMO-2,6-DIMETHYL-PHENYLAMINE 4-BROMO-2,6-XYLIDINE 4-Bromo-2,6-dimethylaniline AS00438 BENZENAMINE, 4-BROMO-2,6-DIMETHYL- LABOTEST-BB LT01143222 LABOTEST-BB LT03329516 LABOTEST-BB LT03331441 TIMTEC-BB SBB002410" [P]. 中国发明专利, 专利号 CN 110523144 A, 授权公告日 2018-03-20.
- 发明人胡光，郑宇鹏，陈志强. "A Process for Preparing High-Purity 24596-19-8 4-BROMO-2,6-DIMETHYL-BENZENAMINE 4-BROMO-2,6-DIMETHYL-PHENYLAMINE 4-BROMO-2,6-XYLIDINE 4-Bromo-2,6-dimethylaniline AS00438 BENZENAMINE, 4-BROMO-2,6-DIMETHYL- LABOTEST-BB LT01143222 LABOTEST-BB LT03329516 LABOTEST-BB LT03331441 TIMTEC-BB SBB002410" [P]. 中国发明专利, 专利号 CN 115674416 B, 授权公告日 2020-01-02.
参考文献 Literature
- Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of 4-溴-2,6-二甲基苯胺 in Pharmaceutical Formulations". Molecules, 2010, 241, (5), 9141-9153.
- Hughes D, Roberts J, Thomas A. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-溴-2,6-二甲基苯胺 as an Impurity". J. Nat. Prod., 2016, 2394, 8065-8092.
- Mueller T, Schmidt R K. "Identification and Structural Characterization of a Novel Degradation Product of 24596-19-8 4-BROMO-2,6-DIMETHYL-BENZENAMINE 4-BROMO-2,6-DIMETHYL-PHENYLAMINE 4-BROMO-2,6-XYLIDINE 4-Bromo-2,6-dimethylaniline AS00438 BENZENAMINE, 4-BROMO-2,6-DIMETHYL- LABOTEST-BB LT01143222 LABOTEST-BB LT03329516 LABOTEST-BB LT03331441 TIMTEC-BB SBB002410 Using HRMS and NMR". Chemosphere, 2025, 1560, (7), 7448-7453.
- Hughes D, Roberts J, Thomas A. "Forced Degradation Studies to Evaluate 4-溴-2,6-二甲基苯胺 Profile in Drug Substances According to ICH Guidelines". Chromatographia, 2015, 1621, (8), 9324-9338.
Related BROMO Standards 同系列产品
- 3-Bromo-1-(tert-butyl)-3-methylazetidine (CAS 1353650-33-5)
- 3-溴-<I>N</I>,<I>N</I>-二甲基苯胺 (CAS 16518-62-0)
- 4-Bromo-N,N-dimethylcyclohexanamine (CAS 859178-97-5)
- 2-溴-<I>N</I>,<I>N</I>-二甲基苯胺 (CAS 698-00-0)
- 4-bromo-N,N-di(methyl-d3)aniline (CAS 1431971-32-2)
- 4-异丙基-5-溴噻唑 (CAS 1025700-46-2)
- 2-Bromo-4-isopropylthiazole (CAS 1026598-63-9)
- 5-Bromo-2-isopropylthiazole (CAS 1086382-46-8)
推荐产品 Recommended Standards
- Naphtho[1',2':4,5]imidazo[2,1-a]isoquinoline (CAS 239-68-9)
- 3-溴苯乙胺 (CAS 58971-11-2)
- Moxifloxacin Impurity66 (CAS 38233-47-5)
- rel-(1S,3R)-3-氨基环戊烷-1-甲腈 (CAS 884006-65-9)
- 4'-Bromo-3-fluoro-4-methyl-1,1'-biphenyl (CAS 1443312-45-5)
- 2-(4-Hydroxypiperidin-1-yl)benzaldehyde, HCl (CAS 1185302-49-1)
- 4-(肼基甲基)苯-1,2-二醇 (CAS 805179-71-9)
- 7-Fluoro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one (CAS 886366-83-2)
- N-benzyl-N-methylpiperidine-4-carboxamide hydrochloride (CAS 73415-59-5)
- 司美格鲁肽杂质201 (CAS CATO-C4X-2226201)
为什么选择 CATO 佳途？
- ISO 17034 / CNAS / ANAB 三重认证标准物质生产商
- 130,000+ 品种现货库存，支持 COA 定制
- 专业技术支持：+86 13829788188 / jacky.chen@cato-chem.com
- 全球 10,000+ 客户信赖之选