Grubbs Catalyst<SUP>®</SUP> M204 CAS 246047-72-3

Tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidene]rut 246047-72-3 (1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(PHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;BENZYLIDENE[1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE]DICHLORO(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;GRUBB'S SECOND GENERATION CATALYST;GRUBBS CATALYST 2ND GENERATION;RUTHENIUM,[1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE]DICHLORO (PHENYLMETHYLENE) (TRICYCLOHEXYLPHOSPHINE);TRICYCLOHEXYLPHOSPHINE[1,3-BIS(2,4,6-TRIMETHYLPHENYL)-4,5-DIHYDROIMIDAZOL-2-YLIDENE][BENZYLIDINE]RUTHENIUM(IV)DICHLORIDE;Tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidene]rut GC10239

纯度 97%+现货药物标准品
CAS 号246047-72-3
分子式C28H32Cl2N2Ru C18H33P
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Grubbs Catalyst<SUP>®</SUP> M204 Tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidene]rut 246047-72-3 (1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(PHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;BENZYLIDENE[1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE]DICHLORO(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;GRUBB'S SECOND GENERATION CATALYST;GRUBBS CATALYST 2ND GENERATION;RUTHENIUM,[1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE]DICHLORO (PHENYLMETHYLENE) (TRICYCLOHEXYLPHOSPHINE);TRICYCLOHEXYLPHOSPHINE[1,3-BIS(2,4,6-TRIMETHYLPHENYL)-4,5-DIHYDROIMIDAZOL-2-YLIDENE][BENZYLIDINE]RUTHENIUM(IV)DICHLORIDE;Tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidene]rut GC10239 CAS 246047-72-3 结构式 Chemical Structure

产品介绍 Description

Grubbs Catalyst<SUP>®</SUP> M204（Tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidene]rut 246047-72-3 (1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(PHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;BENZYLIDENE[1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE]DICHLORO(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;GRUBB'S SECOND GENERATION CATALYST;GRUBBS CATALYST 2ND GENERATION;RUTHENIUM,[1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE]DICHLORO (PHENYLMETHYLENE) (TRICYCLOHEXYLPHOSPHINE);TRICYCLOHEXYLPHOSPHINE[1,3-BIS(2,4,6-TRIMETHYLPHENYL)-4,5-DIHYDROIMIDAZOL-2-YLIDENE][BENZYLIDINE]RUTHENIUM(IV)DICHLORIDE;Tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidene]rut GC10239）是药物分析与质量控制领域常用的药物标准品，CAS 号 246047-72-3。分子式 C28H32Cl2N2Ru C18H33P。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯源要求。适用于GLP实验室的日常分析。 Grubbs Catalyst<SUP>®</SUP> M204（Tricyclohexylphosphine1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidenebenzylidenerut 246047-72-3 (1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(PHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;BENZYLIDENE1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENEDICHLORO(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;GRUBB'S SECOND GENERATION CATALYST;GRUBBS CATALYST 2ND GENERAT

应用场景：Grubbs Catalyst<SUP>®</SUP> M204（Tricyclohexylphosphine 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene benzylidene rut 246047-72-3 (1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(PHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;BENZYLIDENE 1,3-BIS(2,4,6-TRIMETHYLPHENYL

理化性质 Physical & Chemical Properties

中文名称Grubbs Catalyst<SUP>®</SUP> M204
分子式C28H32Cl2N2Ru C18H33P
分子量848.98 g/mol
外观形态淡黄色至黄色无定形粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）14.5
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2025年
卤素含量Cl取代
含氮原子数2

相关专利 Related Patents

  1. 发明人杨光，李文辉，高志强. "一种Grubbs Catalyst<SUP>®</SUP> M204的合成方法" [P]. 中国发明专利, 专利号 CN 108485525 B, 授权公告日 2023-07-14.
  2. Park J H, Thompson G K, Stevens L M. "Method for the Synthesis of Tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidene]rut 246047-72-3 (1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(PHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;BENZYLIDENE[1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE]DICHLORO(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;GRUBB'S SECOND GENERATION CATALYST;GRUBBS CATALYST 2ND GENERATION;RUTHENIUM,[1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE]DICHLORO (PHENYLMETHYLENE) (TRICYCLOHEXYLPHOSPHINE);TRICYCLOHEXYLPHOSPHINE[1,3-BIS(2,4,6-TRIMETHYLPHENYL)-4,5-DIHYDROIMIDAZOL-2-YLIDENE][BENZYLIDINE]RUTHENIUM(IV)DICHLORIDE;Tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidene]rut GC10239" [P]. US Patent, US 11932818 B2, 2018-02-05.

参考文献 Literature

  1. Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of Grubbs Catalyst<SUP>®</SUP> M204 in Pharmaceutical Formulations". Chromatographia, 2018, 1463, (7), 3669-3678.
  2. Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of Grubbs Catalyst<SUP>®</SUP> M204 as an Impurity". J. Chromatogr. A, 2022, 384, (6), 3572-3602.

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