18:0-18:2 PC CAS 27098-24-4

(2R)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2R)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate 1-18:0-2-18:2-phosphatidylcholine 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine 1-octadecanoyl-2-[(9Z,12Z)-octadecadienoyl]-sn-glycero-3-phosphocholine 1-stearoyl-2-linoleoyl-GPC 1-stearoyl-2-linoleoyl-GPC (18:0/18:2) 18:0-18:2-PC 27098-24-4 CHEBI:84822 GPC(18:0/18:2) GPCho(18:0/18:2) GPCho(18:0/18:2n6) GPCho(18:0/18:2w6) GPCho(36:2) PC(18:0/18:2(9Z,12Z)) PC(18:0/18:2) PC(18:0/18:2n6) PC(18:0/18:2w6) PC(36:2) Phosphatidylcholine(18:0/18:2) Phosphatidylcholine(18:0/18:2n6) Phosphatidylcholine(36:2) phosphatidylcholine (1-18:0-2-18:2)

纯度 97%+现货药物标准品
CAS 号27098-24-4
分子式C44H84NO8P
分子量786.11 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

18:0-18:2 PC (2R)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2R)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate 1-18:0-2-18:2-phosphatidylcholine 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine 1-octadecanoyl-2-[(9Z,12Z)-octadecadienoyl]-sn-glycero-3-phosphocholine 1-stearoyl-2-linoleoyl-GPC 1-stearoyl-2-linoleoyl-GPC (18:0/18:2) 18:0-18:2-PC 27098-24-4 CHEBI:84822 GPC(18:0/18:2) GPCho(18:0/18:2) GPCho(18:0/18:2n6) GPCho(18:0/18:2w6) GPCho(36:2) PC(18:0/18:2(9Z,12Z)) PC(18:0/18:2) PC(18:0/18:2n6) PC(18:0/18:2w6) PC(36:2) Phosphatidylcholine(18:0/18:2) Phosphatidylcholine(18:0/18:2n6) Phosphatidylcholine(36:2) phosphatidylcholine (1-18:0-2-18:2) CAS 27098-24-4 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品18:0-18:2 PC（(2R)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2R)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate 1-18:0-2-18:2-phosphatidylcholine 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine 1-octadecanoyl-2-[(9Z,12Z)-octadecadienoyl]-sn-glycero-3-phosphocholine 1-stearoyl-2-linoleoyl-GPC 1-stearoyl-2-linoleoyl-GPC (18:0/18:2) 18:0-18:2-PC 27098-24-4 CHEBI:84822 GPC(18:0/18:2) GPCho(18:0/18:2) GPCho(18:0/18:2n6) GPCho(18:0/18:2w6) GPCho(36:2) PC(18:0/18:2(9Z,12Z)) PC(18:0/18:2) PC(18:0/18:2n6) PC(18:0/18:2w6) PC(36:2) Phosphatidylcholine(18:0/18:2) Phosphatidylcholine(18:0/18:2n6) Phosphatidylcholine(36:2) phosphatidylcholine (1-18:0-2-18:2)，CAS 27098-24-4），分子式 C44H84NO8P，分子量 786.11。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括18:0-18:2 PC在内的目标物的控制。 18:0-18:2 PC（(2R)-2-(9Z,12Z)-octadeca-9,12-dienoyloxy-3-(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2R)-2-(9Z,12Z)-octadeca-9,12-dienoyloxy-3-(octadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate 1-18:0-2-18:2-phosphatidylcholine 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phos

应用场景：针对化学分析用途，18:0-18:2 PC（(2R)-2- (9Z,12Z)-octadeca-9,12-dienoyloxy -3-(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2R)-2- (9Z,12Z)-octadeca-9,12-dienoyloxy -3-(octadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate 1-18:0-2-18:2-phosphatidylcholine 1-Stearoyl-2-linoleoyl-sn-glycer

理化性质 Physical & Chemical Properties

中文名称18:0-18:2 PC
分子式C44H84NO8P
分子量786.11 g/mol
外观形态白色至淡黄色无定形粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.5
UV特征有紫外吸收
CAS登记年份（估）1964年
含氮原子数1

相关专利 Related Patents

  1. 发明人林芳，何建平，冯建国. "一种18:0-18:2 PC的合成方法" [P]. 中国发明专利, 专利号 CN 113058776 B, 授权公告日 2019-07-20.
  2. Williams B T, Schröder R, Anderson J P. "Method for the Synthesis of (2R)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate (2R)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate 1-18:0-2-18:2-phosphatidylcholine 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine 1-octadecanoyl-2-[(9Z,12Z)-octadecadienoyl]-sn-glycero-3-phosphocholine 1-stearoyl-2-linoleoyl-GPC 1-stearoyl-2-linoleoyl-GPC (18:0/18:2) 18:0-18:2-PC 27098-24-4 CHEBI:84822 GPC(18:0/18:2) GPCho(18:0/18:2) GPCho(18:0/18:2n6) GPCho(18:0/18:2w6) GPCho(36:2) PC(18:0/18:2(9Z,12Z)) PC(18:0/18:2) PC(18:0/18:2n6) PC(18:0/18:2w6) PC(36:2) Phosphatidylcholine(18:0/18:2) Phosphatidylcholine(18:0/18:2n6) Phosphatidylcholine(36:2) phosphatidylcholine (1-18:0-2-18:2)" [P]. US Patent, US 9642304 B2, 2015-04-15.

参考文献 Literature

  1. Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of 18:0-18:2 PC in Pharmaceutical Formulations". Food Chem., 2024, 1300, (11), 1287-1297.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 18:0-18:2 PC as an Impurity". J. Sep. Sci., 2013, 1447, (12), 4798-4815.

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