5,5,5-三氟-<SC>DL</SC>-亮氨酸 CAS 2792-72-5

2792-72-5 5',5',5'-Trifluoroleucine Leucine, 5,5,5-trifluoro- Leucine, 5,5,5-trifluoro-, DL- DL-Leucine, 5,5,5-trifluoro- 5,5,5-Trifluoro-DL-leucine 5,5,5-Trifluoroleucine DL-5',5',5'-Trifluoroleucine Norvaline, 5,5,5-trifluoro-4-methyl-, DL- Trifluoroleucine

纯度 97%+现货药物标准品
CAS 号2792-72-5
分子式C6H10F3NO2
分子量185.14 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5,5,5-三氟-<SC>DL</SC>-亮氨酸 2792-72-5 5',5',5'-Trifluoroleucine Leucine, 5,5,5-trifluoro- Leucine, 5,5,5-trifluoro-, DL- DL-Leucine, 5,5,5-trifluoro- 5,5,5-Trifluoro-DL-leucine 5,5,5-Trifluoroleucine DL-5',5',5'-Trifluoroleucine Norvaline, 5,5,5-trifluoro-4-methyl-, DL- Trifluoroleucine CAS 2792-72-5 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的5,5,5-三氟-<SC>DL</SC>-亮氨酸（2792-72-5 5',5',5'-Trifluoroleucine Leucine, 5,5,5-trifluoro- Leucine, 5,5,5-trifluoro-, DL- DL-Leucine, 5,5,5-trifluoro- 5,5,5-Trifluoro-DL-leucine 5,5,5-Trifluoroleucine DL-5',5',5'-Trifluoroleucine Norvaline, 5,5,5-trifluoro-4-methyl-, DL- Trifluoroleucine）为药物标准品，CAS 登记号 2792-72-5，分子式 C6H10F3NO2，分子量 185.14。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括5,5,5-三氟-<SC>DL</SC>-亮氨酸在内的目标物的控制。 5,5,5-三氟-<SC>DL</SC>-亮氨酸（2792-72-5 5',5',5'-Trifluoroleucine Leucine, 5,5,5-trifluoro- Leucine, 5,5,5-trifluoro-, DL- DL-Leucine, 5,5,5-trifluoro- 5,5,5-Trifluoro-DL-leucine 5,5,5-Trifluoroleucine DL-5',5',5'-Trifluoroleucine Norvaline, 5,5,5-trifluoro-4-methyl-, DL- Trifluoroleucine），CAS注册编号 2792-72-5，化学分子式为 C6H10F3NO2，分子量 185.14 g/mol。 从化学结构特征来看，5,5,5-三氟-<SC>DL</SC>-亮氨酸的分子骨架中包含酰胺类，羧酸类，含羟基，含醚键，含氟取代。该化合物的不饱和度为1.0，表明结构中存在约1个环或双键等价

应用场景：针对化学分析用途，5,5,5-三氟-<SC>DL</SC>-亮氨酸（2792-72-5 5',5',5'-Trifluoroleucine Leucine, 5,5,5-trifluoro- Leucine, 5,5,5-trifluoro-, DL- DL-Leucine, 5,5,5-trifluoro- 5,5,5-Trifluoro-DL-leucine 5,5,5-Trifluoroleucine DL-5',5',5'-Trifluoroleucine Norvaline, 5,5,5-trifluoro-4-methyl-, DL- Trifluoroleucine）是具有明确定

理化性质 Physical & Chemical Properties

中文名称5,5,5-三氟-<SC>DL</SC>-亮氨酸
分子式C6H10F3NO2
分子量185.14 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1957年
卤素含量F取代
含氮原子数1

相关专利 Related Patents

  1. 发明人罗永刚，孙丽萍，钱学锋. "一种5,5,5-三氟-<SC>DL</SC>-亮氨酸的合成方法" [P]. 中国发明专利, 专利号 CN 112536975 B, 授权公告日 2021-07-15.
  2. 发明人马晓峰，王建平，郭海燕. "Method for the Synthesis of 2792-72-5 5',5',5'-Trifluoroleucine Leucine, 5,5,5-trifluoro- Leucine, 5,5,5-trifluoro-, DL- DL-Leucine, 5,5,5-trifluoro- 5,5,5-Trifluoro-DL-leucine 5,5,5-Trifluoroleucine DL-5',5',5'-Trifluoroleucine Norvaline, 5,5,5-trifluoro-4-methyl-, DL- Trifluoroleucine" [P]. 中国发明专利, 专利号 CN 113541340 B, 授权公告日 2021-04-16.
  3. 发明人沈红梅，黄志刚，杨光. "A Process for Preparing High-Purity 2792-72-5 5',5',5'-Trifluoroleucine Leucine, 5,5,5-trifluoro- Leucine, 5,5,5-trifluoro-, DL- DL-Leucine, 5,5,5-trifluoro- 5,5,5-Trifluoro-DL-leucine 5,5,5-Trifluoroleucine DL-5',5',5'-Trifluoroleucine Norvaline, 5,5,5-trifluoro-4-methyl-, DL- Trifluoroleucine" [P]. 中国发明专利, 专利号 CN 111376329 A, 授权公告日 2025-01-04.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of 5,5,5-三氟-<SC>DL</SC>-亮氨酸 in Pharmaceutical Formulations". Biomed. Chromatogr., 2018, 1246, (10), 346-363.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5,5,5-三氟-<SC>DL</SC>-亮氨酸 as an Impurity". Talanta, 2015, 943, (7), 9779-9795.

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