硼酸三乙醇胺 CAS 283-56-7

283-56-7 2N1AHN0X56 Boratrane Ethanol, 2,2',2''-nitrilotri-, cyclic borate (7CI) Ethanol, 2,2',2''-nitrilotri-, cyclic ester with boric acid (H3BO3) (1:1) (8CI) 2,8,9-Trioxa-5-aza-1-borabicyclo(3.3.3)undecane 4-04-00-01529 (Beilstein Handbook Reference) Atracor T Boratran Boric acid, tris(2-aminoethyl) ester Boron, ((2,2',2''-nitrilotris(ethanolato))(3-))- BRN 0774536 EINECS 206-003-5 2,2',2''-Nitrilotriethanol cyclic borate NSC 5220 Triethanolamine borate UNII-2N1AHN0X56

纯度 97%+现货药物标准品
CAS 号283-56-7
分子式C6H12BNO3
分子量156.98 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

硼酸三乙醇胺 283-56-7 2N1AHN0X56 Boratrane Ethanol, 2,2',2''-nitrilotri-, cyclic borate (7CI) Ethanol, 2,2',2''-nitrilotri-, cyclic ester with boric acid (H3BO3) (1:1) (8CI) 2,8,9-Trioxa-5-aza-1-borabicyclo(3.3.3)undecane 4-04-00-01529 (Beilstein Handbook Reference) Atracor T Boratran Boric acid, tris(2-aminoethyl) ester Boron, ((2,2',2''-nitrilotris(ethanolato))(3-))- BRN 0774536 EINECS 206-003-5 2,2',2''-Nitrilotriethanol cyclic borate NSC 5220 Triethanolamine borate UNII-2N1AHN0X56 CAS 283-56-7 结构式 Chemical Structure

产品介绍 Description

硼酸三乙醇胺（283-56-7 2N1AHN0X56 Boratrane Ethanol, 2,2',2''-nitrilotri-, cyclic borate (7CI) Ethanol, 2,2',2''-nitrilotri-, cyclic ester with boric acid (H3BO3) (1:1) (8CI) 2,8,9-Trioxa-5-aza-1-borabicyclo(3.3.3)undecane 4-04-00-01529 (Beilstein Handbook Reference) Atracor T Boratran Boric acid, tris(2-aminoethyl) ester Boron, ((2,2',2''-nitrilotris(ethanolato))(3-))- BRN 0774536 EINECS 206-003-5 2,2',2''-Nitrilotriethanol cyclic borate NSC 5220 Triethanolamine borate UNII-2N1AHN0X56，CAS 号 283-56-7）是 CATO 佳途自主生产的药物标准品，分子式 C6H12BNO3，分子量 156.98。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在质量保证方面，硼酸三乙醇胺的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 CAS编号 283-56-7 对应的化合物硼酸三乙醇胺（英文标识 283-56-7 2N1AHN0X56 Boratrane Ethanol, 2,2',2''-nitrilotri-, cyclic borate (7CI) Ethanol, 2,2',2''-nitrilotri-, cyclic ester with boric acid (H3BO3) (1:1) (8CI) 2,8,9-Trioxa-5-aza-1-borabicyclo(3.3.3)undecane 4-04-00-01529 (Beilstein Handbook Reference) Atracor T Boratran Boric acid, tris(2-aminoethyl) ester Boron,

应用场景：硼酸三乙醇胺（283-56-7 2N1AHN0X56 Boratrane Ethanol, 2,2',2''-nitrilotri-, cyclic borate (7CI) Ethanol, 2,2',2''-nitrilotri-, cyclic ester with boric acid (H3BO3) (1:1) (8CI) 2,8,9-Trioxa-5-aza-1-borabicyclo(3.3.3)undecane 4-04-00-01529 (Beilstein Handbook Reference) Atracor T Boratran Boric acid, tris(2-a

理化性质 Physical & Chemical Properties

中文名称硼酸三乙醇胺
分子式C6H12BNO3
分子量156.98 g/mol
外观形态白色至类白色结晶性粉末。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.5
CAS登记年份（估）1957年
含氮原子数1

相关专利 Related Patents

  1. 发明人林芳，唐晓军，刘建华. "一种硼酸三乙醇胺的合成方法" [P]. 中国发明专利, 专利号 CN 117205850 B, 授权公告日 2018-06-11.
  2. Johansson L, Mueller T C, Rossi M. "Method for the Synthesis of 283-56-7 2N1AHN0X56 Boratrane Ethanol, 2,2',2''-nitrilotri-, cyclic borate (7CI) Ethanol, 2,2',2''-nitrilotri-, cyclic ester with boric acid (H3BO3) (1:1) (8CI) 2,8,9-Trioxa-5-aza-1-borabicyclo(3.3.3)undecane 4-04-00-01529 (Beilstein Handbook Reference) Atracor T Boratran Boric acid, tris(2-aminoethyl) ester Boron, ((2,2',2''-nitrilotris(ethanolato))(3-))- BRN 0774536 EINECS 206-003-5 2,2',2''-Nitrilotriethanol cyclic borate NSC 5220 Triethanolamine borate UNII-2N1AHN0X56" [P]. European Patent, EP 3451447 A1, 2019-12-04.
  3. 发明人沈红梅，马晓峰，朱建伟. "A Process for Preparing High-Purity 283-56-7 2N1AHN0X56 Boratrane Ethanol, 2,2',2''-nitrilotri-, cyclic borate (7CI) Ethanol, 2,2',2''-nitrilotri-, cyclic ester with boric acid (H3BO3) (1:1) (8CI) 2,8,9-Trioxa-5-aza-1-borabicyclo(3.3.3)undecane 4-04-00-01529 (Beilstein Handbook Reference) Atracor T Boratran Boric acid, tris(2-aminoethyl) ester Boron, ((2,2',2''-nitrilotris(ethanolato))(3-))- BRN 0774536 EINECS 206-003-5 2,2',2''-Nitrilotriethanol cyclic borate NSC 5220 Triethanolamine borate UNII-2N1AHN0X56" [P]. 中国发明专利, 专利号 CN 117511565 A, 授权公告日 2018-06-17.

参考文献 Literature

  1. Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of 硼酸三乙醇胺 in Pharmaceutical Formulations". Anal. Methods, 2012, 1401, 2663-2682.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 硼酸三乙醇胺 as an Impurity". J. Agric. Food Chem., 2010, 2268, (3), 402-413.
  3. Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of 283-56-7 2N1AHN0X56 Boratrane Ethanol, 2,2',2''-nitrilotri-, cyclic borate (7CI) Ethanol, 2,2',2''-nitrilotri-, cyclic ester with boric acid (H3BO3) (1:1) (8CI) 2,8,9-Trioxa-5-aza-1-borabicyclo(3.3.3)undecane 4-04-00-01529 (Beilstein Handbook Reference) Atracor T Boratran Boric acid, tris(2-aminoethyl) ester Boron, ((2,2',2''-nitrilotris(ethanolato))(3-))- BRN 0774536 EINECS 206-003-5 2,2',2''-Nitrilotriethanol cyclic borate NSC 5220 Triethanolamine borate UNII-2N1AHN0X56 Using HRMS and NMR". J. Chromatogr. A, 2019, 800, (4), 6532-6552.

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