六甘醇十二烷基醚 CAS 3055-96-7

J2N33740SH 3055-96-7 3,6,9,12,15,18-Hexaoxatriacontan-1-ol Hexaoxyethylene dodecyl ether Laureth-6 PEG-6 Lauryl ether Polyethylene glycol 300 lauryl ether Polyoxyethylene (6) lauryl ether 4-01-00-02407 (Beilstein Handbook Reference) BRN 1715367 Dodecyl hexaethylene glycol Dodecyl hexaoxyethylene monoether EINECS 221-282-3 Hexaethylene glycol dodecyl ether Hexaethylene glycol lauryl ether Hexa(oxydiethanol) monodecyl ether Hexaoxyethylene dodecyl monoether Lauryl hexaethoxylate UNII-J2N33740SH

纯度 97%+现货药物标准品
CAS 号3055-96-7
分子式C24H50O7
分子量450.65 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

六甘醇十二烷基醚 J2N33740SH
3055-96-7
3,6,9,12,15,18-Hexaoxatriacontan-1-ol
Hexaoxyethylene dodecyl ether
Laureth-6
PEG-6 Lauryl ether
Polyethylene glycol 300 lauryl ether
Polyoxyethylene (6) lauryl ether
4-01-00-02407 (Beilstein Handbook Reference)
BRN 1715367
Dodecyl hexaethylene glycol
Dodecyl hexaoxyethylene monoether
EINECS 221-282-3
Hexaethylene glycol dodecyl ether
Hexaethylene glycol lauryl ether
Hexa(oxydiethanol) monodecyl ether
Hexaoxyethylene dodecyl monoether
Lauryl hexaethoxylate
UNII-J2N33740SH CAS 3055-96-7 结构式 Chemical Structure

产品介绍 Description

CAS 3055-96-7 对应的六甘醇十二烷基醚(J2N33740SH 3055-96-7 3,6,9,12,15,18-Hexaoxatriacontan-1-ol Hexaoxyethylene dodecyl ether Laureth-6 PEG-6 Lauryl ether Polyethylene glycol 300 lauryl ether Polyoxyethylene (6) lauryl ether 4-01-00-02407 (Beilstein Handbook Reference) BRN 1715367 Dodecyl hexaethylene glycol Dodecyl hexaoxyethylene monoether EINECS 221-282-3 Hexaethylene glycol dodecyl ether Hexaethylene glycol lauryl ether Hexa(oxydiethanol) monodecyl ether Hexaoxyethylene dodecyl monoether Lauryl hexaethoxylate UNII-J2N33740SH)为 CATO 佳途药物标准品产品线成员。分子式 C24H50O7,分子量 450.65。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认,质量稳定可溯源。

六甘醇十二烷基醚的产生途径与其化学式中羧酸类,含羟基,含醚键密切相关,该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 CAS编号 3055-96-7 对应的化合物六甘醇十二烷基醚(英文标识 J2N33740SH 3055-96-7 3,6,9,12,15,18-Hexaoxatriacontan-1-ol Hexaoxyethylene dodecyl ether Laureth-6 PEG-6 Lauryl ether Polyethylene glycol 300 lauryl ether Polyoxyethylene (6) lauryl ether 4-01-00-02407 (Beilstein Handbook Reference) BRN 1715367 Dodecyl hexaethylene glycol Dodecyl hexaoxyethylene monoether EINECS 221-282-3 Hexaethylene glycol dodecyl ether Hexaethylene glycol lauryl ether Hexa(o

应用场景:从实际应用出发,六甘醇十二烷基醚(CAS 3055-96-7)在化学分析中作为关键的基准对照物质。 推荐以六甘醇十二烷基醚配制标准系列工作溶液,用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液,根据检测灵敏度需求逐级稀释。 使用建议: - 称量前将样品在干燥器内平衡至室温(约30分钟); - 储备溶液建议用甲醇配制,于室温保存,密封防潮条件下储存; - 低浓度工作液(<10 μg/mL)建议当天配制使用,不宜长期存放; - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用,防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称六甘醇十二烷基醚
分子式C24H50O7
分子量450.65 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存,密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水(微溶)
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)0.0
CAS登记年份(估)1957年

相关专利 Related Patents

  1. 发明人刘建华,韩伟,沈红梅. "一种六甘醇十二烷基醚的合成方法" [P]. 中国发明专利, 专利号 CN 114023455 A, 授权公告日 2021-09-23.
  2. 发明人张德明,冯建国,马晓峰. "Method for the Synthesis of J2N33740SH 3055-96-7 3,6,9,12,15,18-Hexaoxatriacontan-1-ol Hexaoxyethylene dodecyl ether Laureth-6 PEG-6 Lauryl ether Polyethylene glycol 300 lauryl ether Polyoxyethylene (6) lauryl ether 4-01-00-02407 (Beilstein Handbook Reference) BRN 1715367 Dodecyl hexaethylene glycol Dodecyl hexaoxyethylene monoether EINECS 221-282-3 Hexaethylene glycol dodecyl ether Hexaethylene glycol lauryl ether Hexa(oxydiethanol) monodecyl ether Hexaoxyethylene dodecyl monoether Lauryl hexaethoxylate UNII-J2N33740SH" [P]. 中国发明专利, 专利号 CN 114059268 A, 授权公告日 2015-11-21.
  3. 发明人韩伟,马晓峰,赵玉洁. "A Process for Preparing High-Purity J2N33740SH 3055-96-7 3,6,9,12,15,18-Hexaoxatriacontan-1-ol Hexaoxyethylene dodecyl ether Laureth-6 PEG-6 Lauryl ether Polyethylene glycol 300 lauryl ether Polyoxyethylene (6) lauryl ether 4-01-00-02407 (Beilstein Handbook Reference) BRN 1715367 Dodecyl hexaethylene glycol Dodecyl hexaoxyethylene monoether EINECS 221-282-3 Hexaethylene glycol dodecyl ether Hexaethylene glycol lauryl ether Hexa(oxydiethanol) monodecyl ether Hexaoxyethylene dodecyl monoether Lauryl hexaethoxylate UNII-J2N33740SH" [P]. 中国发明专利, 专利号 CN 116019857 A, 授权公告日 2025-05-27.

参考文献 Literature

  1. Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of 六甘醇十二烷基醚 in Pharmaceutical Formulations". J. Chromatogr. A, 2015, 1658, 2923-2942.
  2. Garcia M, Rodriguez P. "A Stability-Indicating HPLC Method for the Separation and Quantification of 六甘醇十二烷基醚 as an Impurity". Environ. Sci. Technol., 2021, 365, 8342-8351.
  3. Kowalski T, Nowak Z. "Identification and Structural Characterization of a Novel Degradation Product of J2N33740SH 3055-96-7 3,6,9,12,15,18-Hexaoxatriacontan-1-ol Hexaoxyethylene dodecyl ether Laureth-6 PEG-6 Lauryl ether Polyethylene glycol 300 lauryl ether Polyoxyethylene (6) lauryl ether 4-01-00-02407 (Beilstein Handbook Reference) BRN 1715367 Dodecyl hexaethylene glycol Dodecyl hexaoxyethylene monoether EINECS 221-282-3 Hexaethylene glycol dodecyl ether Hexaethylene glycol lauryl ether Hexa(oxydiethanol) monodecyl ether Hexaoxyethylene dodecyl monoether Lauryl hexaethoxylate UNII-J2N33740SH Using HRMS and NMR". Chromatographia, 2011, 303, (10), 8651-8660.
  4. Hughes D, Roberts J, Thomas A. "Forced Degradation Studies to Evaluate 六甘醇十二烷基醚 Profile in Drug Substances According to ICH Guidelines". J. Agric. Food Chem., 2012, 1366, 3721-3732.

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