1,1,4,7,10,10-六甲基三亚乙基四胺 CAS 3083-10-1

0OAF7T9SCQ 3083-10-1 1,1,4,7,10,10-Hexamethyltriethylenetetramine N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethylethylenediamine 1,2-Ethanediamine, N,N'-bis(2-(dimethylamino)ethyl)-N,N'-dimethyl- 1,2-Ethanediamine, N1,N2-bis(2-(dimethylamino)ethyl)-N1,N2-dimethyl- 4-04-00-01247 (Beilstein Handbook Reference) N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethyl-1,2-ethanediamine BRN 1757857 EINECS 221-382-7 Hexamethyltriethylenetetramine N,N,N',N'',N''',N'''-Hexamethyltriethylenetetramine NSC 166488 2,5,8,11-Tetramethyl-2,5,8,11-tetraazadodecane Triethylenetetramine, 1,1,4,7,10,10-hexamethyl- UNII-0OAF7T9SCQ

纯度 97%+现货药物标准品
CAS 号3083-10-1
分子式C12H30N4
分子量230.39 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1,1,4,7,10,10-六甲基三亚乙基四胺 0OAF7T9SCQ 3083-10-1 1,1,4,7,10,10-Hexamethyltriethylenetetramine N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethylethylenediamine 1,2-Ethanediamine, N,N'-bis(2-(dimethylamino)ethyl)-N,N'-dimethyl- 1,2-Ethanediamine, N1,N2-bis(2-(dimethylamino)ethyl)-N1,N2-dimethyl- 4-04-00-01247 (Beilstein Handbook Reference) N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethyl-1,2-ethanediamine BRN 1757857 EINECS 221-382-7 Hexamethyltriethylenetetramine N,N,N',N'',N''',N'''-Hexamethyltriethylenetetramine NSC 166488 2,5,8,11-Tetramethyl-2,5,8,11-tetraazadodecane Triethylenetetramine, 1,1,4,7,10,10-hexamethyl- UNII-0OAF7T9SCQ CAS 3083-10-1 结构式 Chemical Structure

产品介绍 Description

1,1,4,7,10,10-六甲基三亚乙基四胺（0OAF7T9SCQ 3083-10-1 1,1,4,7,10,10-Hexamethyltriethylenetetramine N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethylethylenediamine 1,2-Ethanediamine, N,N'-bis(2-(dimethylamino)ethyl)-N,N'-dimethyl- 1,2-Ethanediamine, N1,N2-bis(2-(dimethylamino)ethyl)-N1,N2-dimethyl- 4-04-00-01247 (Beilstein Handbook Reference) N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethyl-1,2-ethanediamine BRN 1757857 EINECS 221-382-7 Hexamethyltriethylenetetramine N,N,N',N'',N''',N'''-Hexamethyltriethylenetetramine NSC 166488 2,5,8,11-Tetramethyl-2,5,8,11-tetraazadodecane Triethylenetetramine, 1,1,4,7,10,10-hexamethyl- UNII-0OAF7T9SCQ，CAS 号 3083-10-1）是 CATO 佳途自主生产的药物标准品，分子式 C12H30N4，分子量 230.39。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括1,1,4,7,10,10-六甲基三亚乙基四胺在内的目标物的控制。 1,1,4,7,10,10-六甲基三亚乙基四胺（0OAF7T9SCQ 3083-10-1 1,1,4,7,10,10-Hexamethyltriethylenetetramine N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethylethylenediamine 1,2-Ethanediamine, N,N'-bis(2-(dimethylamino)ethyl)-N,N'-dimethyl- 1,2-Ethanediamine, N1,N2-bis(2-(dimethylamino)ethyl)-N1,N2-dimethyl- 4-04-00-01247 (Beilstein Handbook Reference) N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethyl-1,2-ethanediamine BRN 1757857 EINECS 221-382-7 Hexameth

应用场景：从实际应用出发，1,1,4,7,10,10-六甲基三亚乙基四胺（CAS 3083-10-1）在化学分析中作为关键的基准对照物质。 推荐以1,1,4,7,10,10-六甲基三亚乙基四胺配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于2-8°C冷藏保存，避光条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称1,1,4,7,10,10-六甲基三亚乙基四胺
分子式C12H30N4
分子量230.39 g/mol
外观形态白色至类白色低熔点固体
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.0
CAS登记年份（估）1957年
含氮原子数4

相关专利 Related Patents

  1. 发明人黄志刚，何建平，冯建国. "一种1,1,4,7,10,10-六甲基三亚乙基四胺的合成方法" [P]. 中国发明专利, 专利号 CN 108090604 A, 授权公告日 2015-08-19.
  2. Johnson M A, Klinger H, Anderson J P. "Method for the Synthesis of 0OAF7T9SCQ 3083-10-1 1,1,4,7,10,10-Hexamethyltriethylenetetramine N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethylethylenediamine 1,2-Ethanediamine, N,N'-bis(2-(dimethylamino)ethyl)-N,N'-dimethyl- 1,2-Ethanediamine, N1,N2-bis(2-(dimethylamino)ethyl)-N1,N2-dimethyl- 4-04-00-01247 (Beilstein Handbook Reference) N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethyl-1,2-ethanediamine BRN 1757857 EINECS 221-382-7 Hexamethyltriethylenetetramine N,N,N',N'',N''',N'''-Hexamethyltriethylenetetramine NSC 166488 2,5,8,11-Tetramethyl-2,5,8,11-tetraazadodecane Triethylenetetramine, 1,1,4,7,10,10-hexamethyl- UNII-0OAF7T9SCQ" [P]. US Patent, US 9347671 B2, 2021-03-19.
  3. 发明人林芳，马晓峰，黄志刚. "A Process for Preparing High-Purity 0OAF7T9SCQ 3083-10-1 1,1,4,7,10,10-Hexamethyltriethylenetetramine N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethylethylenediamine 1,2-Ethanediamine, N,N'-bis(2-(dimethylamino)ethyl)-N,N'-dimethyl- 1,2-Ethanediamine, N1,N2-bis(2-(dimethylamino)ethyl)-N1,N2-dimethyl- 4-04-00-01247 (Beilstein Handbook Reference) N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethyl-1,2-ethanediamine BRN 1757857 EINECS 221-382-7 Hexamethyltriethylenetetramine N,N,N',N'',N''',N'''-Hexamethyltriethylenetetramine NSC 166488 2,5,8,11-Tetramethyl-2,5,8,11-tetraazadodecane Triethylenetetramine, 1,1,4,7,10,10-hexamethyl- UNII-0OAF7T9SCQ" [P]. 中国发明专利, 专利号 CN 115115364 A, 授权公告日 2017-06-02.

参考文献 Literature

  1. Jensen P, Larsen A M, Olsen K. "Development and Validation of an LC-MS/MS Method for the Determination of 1,1,4,7,10,10-六甲基三亚乙基四胺 in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2020, 1812, 8145-8153.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1,1,4,7,10,10-六甲基三亚乙基四胺 as an Impurity". Rapid Commun. Mass Spectrom., 2018, 1942, 7137-7161.
  3. Smith J A, Johnson M B. "Identification and Structural Characterization of a Novel Degradation Product of 0OAF7T9SCQ 3083-10-1 1,1,4,7,10,10-Hexamethyltriethylenetetramine N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethylethylenediamine 1,2-Ethanediamine, N,N'-bis(2-(dimethylamino)ethyl)-N,N'-dimethyl- 1,2-Ethanediamine, N1,N2-bis(2-(dimethylamino)ethyl)-N1,N2-dimethyl- 4-04-00-01247 (Beilstein Handbook Reference) N,N'-Bis(2-(dimethylamino)ethyl)-N,N'-dimethyl-1,2-ethanediamine BRN 1757857 EINECS 221-382-7 Hexamethyltriethylenetetramine N,N,N',N'',N''',N'''-Hexamethyltriethylenetetramine NSC 166488 2,5,8,11-Tetramethyl-2,5,8,11-tetraazadodecane Triethylenetetramine, 1,1,4,7,10,10-hexamethyl- UNII-0OAF7T9SCQ Using HRMS and NMR". Food Chem., 2025, 729, (1), 9992-10003.

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