二[2-(甲基丙烯酰氧基)乙基]磷酸酯 CAS 32435-46-4

32435-46-4 Q422H5264W Bis(2-(methacryloyloxy)ethyl) phosphate Bis(methacryloyloxyethyl) hydrogen phosphate 2-Propenoic acid, 2-methyl-, 1,1'-(phosphinicobis(oxy-2,1-ethanediyl)) ester 2-Propenoic acid, 2-methyl-, phosphinicobis(oxy-2,1-ethanediyl) ester EINECS 251-040-2 UNII-Q422H5264W

纯度 97%+现货药物标准品
CAS 号32435-46-4
分子式C12H19O8P
分子量322.25 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

二[2-(甲基丙烯酰氧基)乙基]磷酸酯 32435-46-4 Q422H5264W Bis(2-(methacryloyloxy)ethyl) phosphate Bis(methacryloyloxyethyl) hydrogen phosphate 2-Propenoic acid, 2-methyl-, 1,1'-(phosphinicobis(oxy-2,1-ethanediyl)) ester 2-Propenoic acid, 2-methyl-, phosphinicobis(oxy-2,1-ethanediyl) ester EINECS 251-040-2 UNII-Q422H5264W CAS 32435-46-4 结构式 Chemical Structure

产品介绍 Description

CAS 32435-46-4 对应的二[2-(甲基丙烯酰氧基)乙基]磷酸酯（32435-46-4 Q422H5264W Bis(2-(methacryloyloxy)ethyl) phosphate Bis(methacryloyloxyethyl) hydrogen phosphate 2-Propenoic acid, 2-methyl-, 1,1'-(phosphinicobis(oxy-2,1-ethanediyl)) ester 2-Propenoic acid, 2-methyl-, phosphinicobis(oxy-2,1-ethanediyl) ester EINECS 251-040-2 UNII-Q422H5264W）为 CATO 佳途药物标准品产品线成员。分子式 C12H19O8P，分子量 322.25。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的定量分析，可作为外标法校准标准品或系统适用性测试参考物质使用。 化学式为 C12H19O8P 的二2-(甲基丙烯酰氧基)乙基磷酸酯（32435-46-4 Q422H5264W Bis(2-(methacryloyloxy)ethyl) phosphate Bis(methacryloyloxyethyl) hydrogen phosphate 2-Propenoic acid, 2-methyl-, 1,1'-(phosphinicobis(oxy-2,1-ethanediyl)) ester 2-Propenoic acid, 2-methyl-, phosphinicobis(oxy-2,1-ethanediyl) ester EINECS 251-040-2 UNII-Q422H5264W），其CAS登记号是 32435-46-4，分子量为 322.25 g/mol。 受分子结构中含磷酸酯基，羧酸类，含羟基，含醚键的影响，二2-(甲基丙烯酰氧基)乙基磷酸酯表现为白色至类白色结

应用场景：二 2-(甲基丙烯酰氧基)乙基 磷酸酯（32435-46-4 Q422H5264W Bis(2-(methacryloyloxy)ethyl) phosphate Bis(methacryloyloxyethyl) hydrogen phosphate 2-Propenoic acid, 2-methyl-, 1,1'-(phosphinicobis(oxy-2,1-ethanediyl)) ester 2-Propenoic acid, 2-methyl-, phosphinicobis(oxy-2,1-ethanediyl) ester EINECS 251-040-2 UNII-Q422

理化性质 Physical & Chemical Properties

中文名称二[2-(甲基丙烯酰氧基)乙基]磷酸酯
分子式C12H19O8P
分子量322.25 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.5
UV特征有紫外吸收
CAS登记年份（估）1966年

相关专利 Related Patents

  1. 发明人罗永刚，杨光，林芳. "一种二[2-(甲基丙烯酰氧基)乙基]磷酸酯的合成方法" [P]. 中国发明专利, 专利号 CN 114168988 B, 授权公告日 2019-06-14.
  2. 发明人郑宇鹏，郭海燕，王建平. "Method for the Synthesis of 32435-46-4 Q422H5264W Bis(2-(methacryloyloxy)ethyl) phosphate Bis(methacryloyloxyethyl) hydrogen phosphate 2-Propenoic acid, 2-methyl-, 1,1'-(phosphinicobis(oxy-2,1-ethanediyl)) ester 2-Propenoic acid, 2-methyl-, phosphinicobis(oxy-2,1-ethanediyl) ester EINECS 251-040-2 UNII-Q422H5264W" [P]. 中国发明专利, 专利号 CN 111491252 B, 授权公告日 2023-08-25.
  3. 发明人韩伟，胡光，何建平. "A Process for Preparing High-Purity 32435-46-4 Q422H5264W Bis(2-(methacryloyloxy)ethyl) phosphate Bis(methacryloyloxyethyl) hydrogen phosphate 2-Propenoic acid, 2-methyl-, 1,1'-(phosphinicobis(oxy-2,1-ethanediyl)) ester 2-Propenoic acid, 2-methyl-, phosphinicobis(oxy-2,1-ethanediyl) ester EINECS 251-040-2 UNII-Q422H5264W" [P]. 中国发明专利, 专利号 CN 111037152 A, 授权公告日 2021-08-19.

参考文献 Literature

  1. Brown R C, Davis S M. "Development and Validation of an LC-MS/MS Method for the Determination of 二[2-(甲基丙烯酰氧基)乙基]磷酸酯 in Pharmaceutical Formulations". J. Sep. Sci., 2024, 1418, (7), 2968-2986.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 二[2-(甲基丙烯酰氧基)乙基]磷酸酯 as an Impurity". Phytochemistry, 2012, 1075, (8), 8769-8779.
  3. Yang F, Sun W, Liu J. "Identification and Structural Characterization of a Novel Degradation Product of 32435-46-4 Q422H5264W Bis(2-(methacryloyloxy)ethyl) phosphate Bis(methacryloyloxyethyl) hydrogen phosphate 2-Propenoic acid, 2-methyl-, 1,1'-(phosphinicobis(oxy-2,1-ethanediyl)) ester 2-Propenoic acid, 2-methyl-, phosphinicobis(oxy-2,1-ethanediyl) ester EINECS 251-040-2 UNII-Q422H5264W Using HRMS and NMR". Food Chem., 2016, 1465, (3), 7943-7954.

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