乙酰丙酮镍(II) CAS 3264-82-2
3264-82-2 5I48R807JO Nickel acetylacetonate Bis(pentane-2,4-dionato-O,O')nickel Nickel, bis(2,4-pentanedionato)- (8CI) Nickel, bis(2,4-pentanedionato-O,O')- Nickel, bis(2,4-pentanedionato-O,O')-, (SP-4-1)- (9CI) 2,4-Pentanedione, nickel(II) deriv. Nickel, bis(2,4-pentanedionato-kappaO2,kappaO4)-, (SP-4-1)- Nickel, bis(2,4-pentanedionato-kappaO,kappaO')-, (SP-4-1)- Acetylacetonato nickel Acetylacetonatonickel (II) AI3-26159 Bis(acetylacetonate)nickel Bis(acetylacetonate)nickel (VAN) Bis(acetylacetonato)nickel Bis(acetylacetone)nickel Bis(2,4-pentanedionato)nickel Bis-2,4-pentanedionatonickel(II) EINECS 221-875-7 Nickel acetonylacetonate Nickel(2+) acetylacetonate Nickel bis(acetylacetonate) Nickel bis(2,4-pentanedionate) Nickel, bis(2,4-pentanedionato-O,O')-, (SP-4-1) Nickel(II) acetylacetonate Nickelous acetylacetonate Ni(II) Acetylacetone complex (1:2) NSC 4657 2,4-Pentanedione, nickel(II)deriv. UNII-5I48R807JO
| CAS 号 | 3264-82-2 |
| 分子式 | C10H14NiO4 |
| 分子量 | 256.91 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
乙酰丙酮镍(II)（英文名 3264-82-2 5I48R807JO Nickel acetylacetonate Bis(pentane-2,4-dionato-O,O')nickel Nickel, bis(2,4-pentanedionato)- (8CI) Nickel, bis(2,4-pentanedionato-O,O')- Nickel, bis(2,4-pentanedionato-O,O')-, (SP-4-1)- (9CI) 2,4-Pentanedione, nickel(II) deriv. Nickel, bis(2,4-pentanedionato-kappaO2,kappaO4)-, (SP-4-1)- Nickel, bis(2,4-pentanedionato-kappaO,kappaO')-, (SP-4-1)- Acetylacetonato nickel Acetylacetonatonickel (II) AI3-26159 Bis(acetylacetonate)nickel Bis(acetylacetonate)nickel (VAN) Bis(acetylacetonato)nickel Bis(acetylacetone)nickel Bis(2,4-pentanedionato)nickel Bis-2,4-pentanedionatonickel(II) EINECS 221-875-7 Nickel acetonylacetonate Nickel(2+) acetylacetonate Nickel bis(acetylacetonate) Nickel bis(2,4-pentanedionate) Nickel, bis(2,4-pentanedionato-O,O')-, (SP-4-1) Nickel(II) acetylacetonate Nickelous acetylacetonate Ni(II) Acetylacetone complex (1:2) NSC 4657 2,4-Pentanedione, nickel(II)deriv. UNII-5I48R807JO，CAS 3264-82-2）属于药物标准品。分子式 C10H14NiO4，分子量 256.91。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。
CAS编号 3264-82-2 对应的化合物乙酰丙酮镍(II)（英文标识 3264-82-2 5I48R807JO Nickel acetylacetonate Bis(pentane-2,4-dionato-O,O')nickel Nickel, bis(2,4-pentanedionato)- (8CI) Nickel, bis(2,4-pentanedionato-O,O')- Nickel, bis(2,4-pentanedionato-O,O')-, (SP-4-1)- (9CI) 2,4-Pentanedione, nickel(II) deriv. Nickel, bis(2,4-pentanedionato-kappaO2,kappaO4)-, (SP-4-1)- Nickel, bis(2,4-pentanedionato-kappaO,kappaO')-, (SP-4-1)- Acetylacetonato nickel Acetylacetonatonickel (II) AI3-26159 Bis(acetylacetonate)nickel Bis(acety
应用场景：针对化学分析用途，乙酰丙酮镍(II)（3264-82-2 5I48R807JO Nickel acetylacetonate Bis(pentane-2,4-dionato-O,O')nickel Nickel, bis(2,4-pentanedionato)- (8CI) Nickel, bis(2,4-pentanedionato-O,O')- Nickel, bis(2,4-pentanedionato-O,O')-, (SP-4-1)- (9CI) 2,4-Pentanedione, nickel(II) deriv. Nickel, bis(2,4-pentanedionato-ka
理化性质 Physical & Chemical Properties
| 中文名称 | 乙酰丙酮镍(II) |
| 分子式 | C10H14NiO4 |
| 分子量 | 256.91 g/mol |
| 外观形态 | 类白色至淡黄色结晶性粉末 |
| 纯度 | 97%+ |
| 储存条件 | 阴凉处（≤25°C）保存，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙醇、DMSO |
| 稳定性 | 空气中长期暴露可能发生缓慢氧化；具有吸湿性，开封后应立即密封 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 4.0 |
| UV特征 | 有紫外吸收 |
| 结构特征 | 含芳环 |
| CAS登记年份（估） | 1957年 |
相关专利 Related Patents
- 发明人孙丽萍，黄志刚，高志强. "一种乙酰丙酮镍(II)的合成方法" [P]. 中国发明专利, 专利号 CN 115989343 B, 授权公告日 2024-12-23.
- 发明人王建平，胡光，张德明. "Method for the Synthesis of 3264-82-2 5I48R807JO Nickel acetylacetonate Bis(pentane-2,4-dionato-O,O')nickel Nickel, bis(2,4-pentanedionato)- (8CI) Nickel, bis(2,4-pentanedionato-O,O')- Nickel, bis(2,4-pentanedionato-O,O')-, (SP-4-1)- (9CI) 2,4-Pentanedione, nickel(II) deriv. Nickel, bis(2,4-pentanedionato-kappaO2,kappaO4)-, (SP-4-1)- Nickel, bis(2,4-pentanedionato-kappaO,kappaO')-, (SP-4-1)- Acetylacetonato nickel Acetylacetonatonickel (II) AI3-26159 Bis(acetylacetonate)nickel Bis(acetylacetonate)nickel (VAN) Bis(acetylacetonato)nickel Bis(acetylacetone)nickel Bis(2,4-pentanedionato)nickel Bis-2,4-pentanedionatonickel(II) EINECS 221-875-7 Nickel acetonylacetonate Nickel(2+) acetylacetonate Nickel bis(acetylacetonate) Nickel bis(2,4-pentanedionate) Nickel, bis(2,4-pentanedionato-O,O')-, (SP-4-1) Nickel(II) acetylacetonate Nickelous acetylacetonate Ni(II) Acetylacetone complex (1:2) NSC 4657 2,4-Pentanedione, nickel(II)deriv. UNII-5I48R807JO" [P]. 中国发明专利, 专利号 CN 113794858 B, 授权公告日 2022-11-18.
参考文献 Literature
- Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of 乙酰丙酮镍(II) in Pharmaceutical Formulations". J. Chromatogr. A, 2012, 1185, 7319-7349.
- Fischer P, Wagner E. "A Stability-Indicating HPLC Method for the Separation and Quantification of 乙酰丙酮镍(II) as an Impurity". J. Pharm. Biomed. Anal., 2020, 1981, 3161-3171.
- Mueller T, Schmidt R K. "Identification and Structural Characterization of a Novel Degradation Product of 3264-82-2 5I48R807JO Nickel acetylacetonate Bis(pentane-2,4-dionato-O,O')nickel Nickel, bis(2,4-pentanedionato)- (8CI) Nickel, bis(2,4-pentanedionato-O,O')- Nickel, bis(2,4-pentanedionato-O,O')-, (SP-4-1)- (9CI) 2,4-Pentanedione, nickel(II) deriv. Nickel, bis(2,4-pentanedionato-kappaO2,kappaO4)-, (SP-4-1)- Nickel, bis(2,4-pentanedionato-kappaO,kappaO')-, (SP-4-1)- Acetylacetonato nickel Acetylacetonatonickel (II) AI3-26159 Bis(acetylacetonate)nickel Bis(acetylacetonate)nickel (VAN) Bis(acetylacetonato)nickel Bis(acetylacetone)nickel Bis(2,4-pentanedionato)nickel Bis-2,4-pentanedionatonickel(II) EINECS 221-875-7 Nickel acetonylacetonate Nickel(2+) acetylacetonate Nickel bis(acetylacetonate) Nickel bis(2,4-pentanedionate) Nickel, bis(2,4-pentanedionato-O,O')-, (SP-4-1) Nickel(II) acetylacetonate Nickelous acetylacetonate Ni(II) Acetylacetone complex (1:2) NSC 4657 2,4-Pentanedione, nickel(II)deriv. UNII-5I48R807JO Using HRMS and NMR". Anal. Methods, 2025, 844, 4310-4322.
- O'Brien K, Kennedy M L. "Forced Degradation Studies to Evaluate 乙酰丙酮镍(II) Profile in Drug Substances According to ICH Guidelines". Biomed. Chromatogr., 2021, 715, 1554-1567.
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