1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde CAS 327085-05-2

1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde

纯度 97%+现货药物标准品
CAS 号327085-05-2
分子式C14H11ClF3NO
分子量301.69 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde 1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde CAS 327085-05-2 结构式 Chemical Structure

产品介绍 Description

1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde（1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde）是药物分析与质量控制领域常用的药物标准品，CAS 号 327085-05-2。分子式 C14H11ClF3NO，分子量 301.69。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde的产生途径与其化学式中含氮杂环结构，酰胺类，含羟基，含醚键，含氟/氯取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde（1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde），CAS注册编号 327085-05-2，化学分子式为 C14H11ClF3NO，分子量 301.69 g/mol。 1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde（C14H11ClF3NO）含有含氮杂环结构，酰胺类，含羟基，含醚键，含氟/氯取代。卤素取代增加了化合物的密度和沸点，较高

应用场景：1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde（1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1

理化性质 Physical & Chemical Properties

中文名称1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde
分子式C14H11ClF3NO
分子量301.69 g/mol
外观形态淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）8.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2025年
卤素含量F/Cl取代
含氮原子数1

相关专利 Related Patents

  1. 发明人钱学锋，沈红梅，何建平. "一种1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde的合成方法" [P]. 中国发明专利, 专利号 CN 117617390 B, 授权公告日 2021-02-24.
  2. 发明人张德明，刘建华，何建平. "Method for the Synthesis of 1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde" [P]. 中国发明专利, 专利号 CN 114945744 A, 授权公告日 2021-09-19.

参考文献 Literature

  1. Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of 1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde in Pharmaceutical Formulations". Anal. Chem., 2025, 2371, (9), 3254-3273.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde as an Impurity". J. Agric. Food Chem., 2020, 2366, 4992-5004.
  3. Yang F, Sun W, Liu J. "Identification and Structural Characterization of a Novel Degradation Product of 1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde Using HRMS and NMR". Biomed. Chromatogr., 2012, 1131, 9961-9985.
  4. Yang F, Sun W, Liu J. "Forced Degradation Studies to Evaluate 1-(2-Chloro-5-trifluoromethyl-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde Profile in Drug Substances According to ICH Guidelines". J. Pharm. Biomed. Anal., 2010, 905, (1), 3885-3913.

Related Chloro Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...