Indoxyl phosphate disodium salt CAS 3318-43-2

P1W2D6403E 3318-43-2 Indol-3-yl sodium phosphate Disodium indol-3-yl phosphate 1H-Indol-3-ol, 3-(dihydrogen phosphate), sodium salt (1:2) 1H-Indol-3-ol, dihydrogen phosphate (ester), disodium salt EINECS 222-014-8 Indoxylphosphate, disodium salt UNII-P1W2D6403E Disodium indoxylphosphate

纯度 97%+现货药物标准品
CAS 号3318-43-2
分子式C8H14NO4P 2*Na
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Indoxyl phosphate disodium salt P1W2D6403E 3318-43-2 Indol-3-yl sodium phosphate Disodium indol-3-yl phosphate 1H-Indol-3-ol, 3-(dihydrogen phosphate), sodium salt (1:2) 1H-Indol-3-ol, dihydrogen phosphate (ester), disodium salt EINECS 222-014-8 Indoxylphosphate, disodium salt UNII-P1W2D6403E Disodium indoxylphosphate CAS 3318-43-2 结构式 Chemical Structure

产品介绍 Description

CAS 3318-43-2 对应的Indoxyl phosphate disodium salt（P1W2D6403E 3318-43-2 Indol-3-yl sodium phosphate Disodium indol-3-yl phosphate 1H-Indol-3-ol, 3-(dihydrogen phosphate), sodium salt (1:2) 1H-Indol-3-ol, dihydrogen phosphate (ester), disodium salt EINECS 222-014-8 Indoxylphosphate, disodium salt UNII-P1W2D6403E Disodium indoxylphosphate）为 CATO 佳途药物标准品产品线成员。分子式 C8H14NO4P 2*Na。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

CAS编号 3318-43-2 对应的化合物Indoxyl phosphate disodium salt（英文标识 P1W2D6403E 3318-43-2 Indol-3-yl sodium phosphate Disodium indol-3-yl phosphate 1H-Indol-3-ol, 3-(dihydrogen phosphate), sodium salt (1:2) 1H-Indol-3-ol, dihydrogen phosphate (ester), disodium salt EINECS 222-014-8 Indoxylphosphate, disodium salt UNII-P1W2D6403E Disodium indoxylphosphate），化学式 C8H14NO4P 2Na，相对分子质量 242.17。 Indoxyl phosphate disodium salt（C8H14NO4P 2Na）含有酰胺类，含磷酸酯基，羧酸类，含羟基，含醚键。具有较强的吸湿性，羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方

应用场景：Indoxyl phosphate disodium salt（P1W2D6403E 3318-43-2 Indol-3-yl sodium phosphate Disodium indol-3-yl phosphate 1H-Indol-3-ol, 3-(dihydrogen phosphate), sodium salt (1:2) 1H-Indol-3-ol, dihydrogen phosphate (ester), disodium salt EINECS 222-014-8 Indoxylphosphate, disodium salt UNII-P1W2D6403E Disodi

理化性质 Physical & Chemical Properties

中文名称Indoxyl phosphate disodium salt
分子式C8H14NO4P 2*Na
分子量242.17 g/mol
外观形态白色至类白色结晶性粉末。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.5
CAS登记年份（估）1957年
含氮原子数1

相关专利 Related Patents

  1. 发明人周伟，唐晓军，李文辉. "一种Indoxyl phosphate disodium salt的合成方法" [P]. 中国发明专利, 专利号 CN 115086971 A, 授权公告日 2019-08-17.
  2. Sørensen M, Schröder R, Rossi M. "Method for the Synthesis of P1W2D6403E 3318-43-2 Indol-3-yl sodium phosphate Disodium indol-3-yl phosphate 1H-Indol-3-ol, 3-(dihydrogen phosphate), sodium salt (1:2) 1H-Indol-3-ol, dihydrogen phosphate (ester), disodium salt EINECS 222-014-8 Indoxylphosphate, disodium salt UNII-P1W2D6403E Disodium indoxylphosphate" [P]. European Patent, EP 3817577 A1, 2020-06-04.
  3. Nielsen H, Sørensen M, Johansson L. "A Process for Preparing High-Purity P1W2D6403E 3318-43-2 Indol-3-yl sodium phosphate Disodium indol-3-yl phosphate 1H-Indol-3-ol, 3-(dihydrogen phosphate), sodium salt (1:2) 1H-Indol-3-ol, dihydrogen phosphate (ester), disodium salt EINECS 222-014-8 Indoxylphosphate, disodium salt UNII-P1W2D6403E Disodium indoxylphosphate" [P]. European Patent, EP 3392684 A1, 2020-11-19.

参考文献 Literature

  1. Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of Indoxyl phosphate disodium salt in Pharmaceutical Formulations". J. Agric. Food Chem., 2021, 353, 2220-2234.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of Indoxyl phosphate disodium salt as an Impurity". Food Chem., 2015, 1727, 1298-1303.
  3. O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of P1W2D6403E 3318-43-2 Indol-3-yl sodium phosphate Disodium indol-3-yl phosphate 1H-Indol-3-ol, 3-(dihydrogen phosphate), sodium salt (1:2) 1H-Indol-3-ol, dihydrogen phosphate (ester), disodium salt EINECS 222-014-8 Indoxylphosphate, disodium salt UNII-P1W2D6403E Disodium indoxylphosphate Using HRMS and NMR". Anal. Chem., 2020, 1455, 6435-6438.

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