C18:1 Dihydroceramide (d18:0/18:1(9Z)) CAS 34227-83-3

(9Z)-N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]octadec-9-enamide 34227-83-3 C18:1DH Cer CHEBI:74100 Cer(d18:0/18:1(9Z)) N-(9Z-octadecenoyl)-sphinganine N-(9Z-octadecenoyl)dihydroceramide N-(oleoyl)dihydroceramide N-C18:1 sphinganine N-[(9Z)-octadecenoyl]dihydrosphingosine N-[(9Z)-octadecenoyl]sphinganine N-oleoyldihydrosphingosine N-oleoylsphinganine

纯度 97%+现货药物标准品
CAS 号34227-83-3
分子式C36H71NO3
分子量565.95 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

C18:1 Dihydroceramide (d18:0/18:1(9Z)) (9Z)-N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]octadec-9-enamide 34227-83-3 C18:1DH Cer CHEBI:74100 Cer(d18:0/18:1(9Z)) N-(9Z-octadecenoyl)-sphinganine N-(9Z-octadecenoyl)dihydroceramide N-(oleoyl)dihydroceramide N-C18:1 sphinganine N-[(9Z)-octadecenoyl]dihydrosphingosine N-[(9Z)-octadecenoyl]sphinganine N-oleoyldihydrosphingosine N-oleoylsphinganine CAS 34227-83-3 结构式 Chemical Structure

产品介绍 Description

CAS 34227-83-3 对应的C18:1 Dihydroceramide (d18:0/18:1(9Z))（(9Z)-N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]octadec-9-enamide 34227-83-3 C18:1DH Cer CHEBI:74100 Cer(d18:0/18:1(9Z)) N-(9Z-octadecenoyl)-sphinganine N-(9Z-octadecenoyl)dihydroceramide N-(oleoyl)dihydroceramide N-C18:1 sphinganine N-[(9Z)-octadecenoyl]dihydrosphingosine N-[(9Z)-octadecenoyl]sphinganine N-oleoyldihydrosphingosine N-oleoylsphinganine）为 CATO 佳途药物标准品产品线成员。分子式 C36H71NO3，分子量 565.95。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

CAS编号 34227-83-3 对应的化合物C18:1 Dihydroceramide (d18:0/18:1(9Z))（英文标识 (9Z)-N-(2S,3R)-1,3-dihydroxyoctadecan-2-yloctadec-9-enamide 34227-83-3 C18:1DH Cer CHEBI:74100 Cer(d18:0/18:1(9Z)) N-(9Z-octadecenoyl)-sphinganine N-(9Z-octadecenoyl)dihydroceramide N-(oleoyl)dihydroceramide N-C18:1 sphinganine N-(9Z)-octadecenoyldihydrosphingosine N-(9Z)-octadecenoylsphinganine N-oleoyldihydrosphingosine N-oleoylsphinganine），化学式 C36H71NO3，相对分子质量 565.95。 从化学结构特征来看，C18:1 Dihydroceramide (d18:0/18:1(9Z))的分子骨

应用场景：C18:1 Dihydroceramide (d18:0/18:1(9Z))（(9Z)-N- (2S,3R)-1,3-dihydroxyoctadecan-2-yl octadec-9-enamide 34227-83-3 C18:1DH Cer CHEBI:74100 Cer(d18:0/18:1(9Z)) N-(9Z-octadecenoyl)-sphinganine N-(9Z-octadecenoyl)dihydroceramide N-(oleoyl)dihydroceramide N-C18:1 sphinganine N- (9Z)-octadecenoyl dihydrosph

理化性质 Physical & Chemical Properties

中文名称C18:1 Dihydroceramide (d18:0/18:1(9Z))
分子式C36H71NO3
分子量565.95 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1966年
含氮原子数1

相关专利 Related Patents

  1. 发明人杨光，周伟，郭海燕. "一种C18:1 Dihydroceramide (d18:0/18:1(9Z))的合成方法" [P]. 中国发明专利, 专利号 CN 112458887 A, 授权公告日 2024-09-03.
  2. 发明人马晓峰，胡光，赵玉洁. "Method for the Synthesis of (9Z)-N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]octadec-9-enamide 34227-83-3 C18:1DH Cer CHEBI:74100 Cer(d18:0/18:1(9Z)) N-(9Z-octadecenoyl)-sphinganine N-(9Z-octadecenoyl)dihydroceramide N-(oleoyl)dihydroceramide N-C18:1 sphinganine N-[(9Z)-octadecenoyl]dihydrosphingosine N-[(9Z)-octadecenoyl]sphinganine N-oleoyldihydrosphingosine N-oleoylsphinganine" [P]. 中国发明专利, 专利号 CN 110862466 B, 授权公告日 2024-09-07.

参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of C18:1 Dihydroceramide (d18:0/18:1(9Z)) in Pharmaceutical Formulations". Talanta, 2025, 2470, (3), 353-377.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of C18:1 Dihydroceramide (d18:0/18:1(9Z)) as an Impurity". Anal. Methods, 2010, 1635, (9), 4878-4895.

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