2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester CAS 365542-75-2

2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester

纯度 97%+现货药物标准品
CAS 号365542-75-2
分子式C23H22N2O5
分子量406.43 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester 2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester CAS 365542-75-2 结构式 Chemical Structure

产品介绍 Description

2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester（英文名 2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester，CAS 365542-75-2）属于药物标准品。分子式 C23H22N2O5，分子量 406.43。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括2-2-(2-Dimethylamino-6-oxo-4-phenyl-6H-1,3oxazin-5-yl)-vinyl-6-methoxy-benzoic acid methyl ester在内的目标物的控制。 CAS编号 365542-75-2 对应的化合物2-2-(2-Dimethylamino-6-oxo-4-phenyl-6H-1,3oxazin-5-yl)-vinyl-6-methoxy-benzoic acid methyl ester（英文标识 2-2-(2-Dimethylamino-6-oxo-4-phenyl-6H-1,3oxazin-5-yl)-vinyl-6-methoxy-benzoic acid methyl ester），化学式 C23H22N2O5，相对分子质量 406.43。 从化学结构特征来看，2-2-(2-Dimethylamino-6-oxo-4-phenyl-6H-1,3oxazin-5-yl)-vinyl-6-methoxy-benzoic ac

应用场景：2- 2-(2-Dimethylamino-6-oxo-4-phenyl-6H- 1,3 oxazin-5-yl)-vinyl -6-methoxy-benzoic acid methyl ester（2- 2-(2-Dimethylamino-6-oxo-4-phenyl-6H- 1,3 oxazin-5-yl)-vinyl -6-methoxy-benzoic acid methyl ester）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以2- 2-(2-Dimethylamino-6-oxo-4-phenyl-6H- 1,3 oxazin-5-yl)-vinyl -6-

理化性质 Physical & Chemical Properties

中文名称2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester
分子式C23H22N2O5
分子量406.43 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）14.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2025年
含氮原子数2

相关专利 Related Patents

  1. 发明人唐晓军，高志强，马晓峰. "一种2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester的合成方法" [P]. 中国发明专利, 专利号 CN 117013311 A, 授权公告日 2022-03-11.
  2. 发明人李文辉，刘建华，徐明华. "Method for the Synthesis of 2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester" [P]. 中国发明专利, 专利号 CN 112381138 B, 授权公告日 2019-12-08.
  3. Sørensen M, Rossi M, Björnsson E. "A Process for Preparing High-Purity 2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester" [P]. European Patent, EP 3306262 A1, 2020-05-12.

参考文献 Literature

  1. Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of 2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester in Pharmaceutical Formulations". Environ. Sci. Technol., 2017, 2258, (5), 4908-4915.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester as an Impurity". Biomed. Chromatogr., 2011, 1993, (5), 7063-7090.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 2-[2-(2-Dimethylamino-6-oxo-4-phenyl-6H-[1,3]oxazin-5-yl)-vinyl]-6-methoxy-benzoic acid methyl ester Using HRMS and NMR". J. Pharm. Biomed. Anal., 2011, 1574, (7), 8060-8081.

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