二氢乙锭 CAS 38483-26-0

38483-26-0 Hydroethidine Phenanthridine, 5,6-dihydro-3,8-diamino-5-ethyl-6-phenyl- BRN 5107482 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine 5,6-Dihydro-3,8-diamino-5-ethyl-6-phenylphenanthridine Reduced ethidium

纯度 97%+现货药物标准品
CAS 号38483-26-0
分子式C21H21N3
分子量315.41 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

二氢乙锭 38483-26-0 Hydroethidine Phenanthridine, 5,6-dihydro-3,8-diamino-5-ethyl-6-phenyl- BRN 5107482 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine 5,6-Dihydro-3,8-diamino-5-ethyl-6-phenylphenanthridine Reduced ethidium CAS 38483-26-0 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品二氢乙锭（38483-26-0 Hydroethidine Phenanthridine, 5,6-dihydro-3,8-diamino-5-ethyl-6-phenyl- BRN 5107482 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine 5,6-Dihydro-3,8-diamino-5-ethyl-6-phenylphenanthridine Reduced ethidium，CAS 38483-26-0），分子式 C21H21N3，分子量 315.41。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

二氢乙锭的产生途径与其化学式中含氮杂环结构，含氰基密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 CAS编号 38483-26-0 对应的化合物二氢乙锭（英文标识 38483-26-0 Hydroethidine Phenanthridine, 5,6-dihydro-3,8-diamino-5-ethyl-6-phenyl- BRN 5107482 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine 5,6-Dihydro-3,8-diamino-5-ethyl-6-phenylphenanthridine Reduced ethidium），化学式 C21H21N3，相对分子质量 315.41。 从化学结构特征来看，二氢乙锭的分子骨架中包含含氮杂环结构，含氰基。该化合物的不饱和度为13.0，表明结构中存在约13个环或双键等价单元。分子量为315.41 g/mol，属于较高分子量化合物。较高的碳氢原子比赋予该化合物良好的脂溶性，可使用正己烷或乙酸乙酯等非极性溶剂进行液-液萃取前处理。 本品适用于

应用场景：针对化学分析用途，二氢乙锭（38483-26-0 Hydroethidine Phenanthridine, 5,6-dihydro-3,8-diamino-5-ethyl-6-phenyl- BRN 5107482 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine 5,6-Dihydro-3,8-diamino-5-ethyl-6-phenylphenanthridine Reduced ethidium）是具有明确定量溯源的认证级对照品。 推荐以二氢乙锭配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配

理化性质 Physical & Chemical Properties

中文名称二氢乙锭
分子式C21H21N3
分子量315.41 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）13.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1967年
含氮原子数3

相关专利 Related Patents

  1. 发明人钱学锋，杨光，陈志强. "一种二氢乙锭的合成方法" [P]. 中国发明专利, 专利号 CN 116329790 B, 授权公告日 2020-02-04.
  2. Martínez F, Sørensen M, Nowak P. "Method for the Synthesis of 38483-26-0 Hydroethidine Phenanthridine, 5,6-dihydro-3,8-diamino-5-ethyl-6-phenyl- BRN 5107482 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine 5,6-Dihydro-3,8-diamino-5-ethyl-6-phenylphenanthridine Reduced ethidium" [P]. European Patent, EP 3798317 A1, 2017-05-21.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of 二氢乙锭 in Pharmaceutical Formulations". Anal. Methods, 2025, 2425, 4012-4028.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 二氢乙锭 as an Impurity". Environ. Sci. Technol., 2014, 1447, 4566-4588.
  3. O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of 38483-26-0 Hydroethidine Phenanthridine, 5,6-dihydro-3,8-diamino-5-ethyl-6-phenyl- BRN 5107482 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine 5,6-Dihydro-3,8-diamino-5-ethyl-6-phenylphenanthridine Reduced ethidium Using HRMS and NMR". Biomed. Chromatogr., 2020, 2005, 2492-2508.

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