16,16-二甲基前列腺素 E<SUB>2</SUB> CAS 39746-25-3

M790V82VAC 39746-25-3 16,16-Dimethylprostaglandin E2 16,16-Dimethyl prostaglandin E2 Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (5Z,11-alpha,13E,15R)- BRN 2896843 (5Z,11-alpha,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid 7-(2-(4,4-Dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)-5-heptenoic acid 16,16-Dimethyl-pge2 16,16-Dimethyl-prostaglandin E2 5-Heptenoic acid, 7-(2-(4,4-dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)- UNII-M790V82VAC FT1050

纯度 97%+现货药物标准品
CAS 号39746-25-3
分子式C22H36O5
分子量380.52 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

16,16-二甲基前列腺素 E<SUB>2</SUB> M790V82VAC 39746-25-3 16,16-Dimethylprostaglandin E2 16,16-Dimethyl prostaglandin E2 Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (5Z,11-alpha,13E,15R)- BRN 2896843 (5Z,11-alpha,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid 7-(2-(4,4-Dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)-5-heptenoic acid 16,16-Dimethyl-pge2 16,16-Dimethyl-prostaglandin E2 5-Heptenoic acid, 7-(2-(4,4-dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)- UNII-M790V82VAC FT1050 CAS 39746-25-3 结构式 Chemical Structure

产品介绍 Description

16,16-二甲基前列腺素 E<SUB>2</SUB>（英文名 M790V82VAC 39746-25-3 16,16-Dimethylprostaglandin E2 16,16-Dimethyl prostaglandin E2 Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (5Z,11-alpha,13E,15R)- BRN 2896843 (5Z,11-alpha,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid 7-(2-(4,4-Dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)-5-heptenoic acid 16,16-Dimethyl-pge2 16,16-Dimethyl-prostaglandin E2 5-Heptenoic acid, 7-(2-(4,4-dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)- UNII-M790V82VAC FT1050，CAS 39746-25-3）属于药物标准品。分子式 C22H36O5，分子量 380.52。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

16,16-二甲基前列腺素 E<SUB>2</SUB>（分子式 C22H36O5）的化学结构中包含甾体骨架，含羟基，含醚键。在反相色谱体系中，其保留行为主要受官能团的极性和离子化状态影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。分子中包含芳环或共轭体系，在UV-Vis光谱中具有特征性吸收带，适用于紫外或二极管阵列检测器（DAD）的定量分析。 化学式为 C22H36O5 的16,16-二甲基前列腺素 E<SUB>2</SUB>（M790V82VAC 39746-25-3 16,16-Dimethylprostaglandin E2 16,16-Dimethyl prostaglandin E2 Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (5Z,11-alpha,13E,15R)- BRN 2896843 (5Z,11-alpha,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic aci

应用场景：16,16-二甲基前列腺素 E<SUB>2</SUB>（M790V82VAC 39746-25-3 16,16-Dimethylprostaglandin E2 16,16-Dimethyl prostaglandin E2 Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (5Z,11-alpha,13E,15R)- BRN 2896843 (5Z,11-alpha,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic aci

理化性质 Physical & Chemical Properties

中文名称16,16-二甲基前列腺素 E<SUB>2</SUB>
分子式C22H36O5
分子量380.52 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件室温保存，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1968年

相关专利 Related Patents

  1. 发明人沈红梅，黄志刚，钱学锋. "一种16,16-二甲基前列腺素 E<SUB>2</SUB>的合成方法" [P]. 中国发明专利, 专利号 CN 110116869 A, 授权公告日 2015-12-14.
  2. 发明人郑宇鹏，高志强，王建平. "Method for the Synthesis of M790V82VAC 39746-25-3 16,16-Dimethylprostaglandin E2 16,16-Dimethyl prostaglandin E2 Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (5Z,11-alpha,13E,15R)- BRN 2896843 (5Z,11-alpha,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid 7-(2-(4,4-Dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)-5-heptenoic acid 16,16-Dimethyl-pge2 16,16-Dimethyl-prostaglandin E2 5-Heptenoic acid, 7-(2-(4,4-dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)- UNII-M790V82VAC FT1050" [P]. 中国发明专利, 专利号 CN 115472352 B, 授权公告日 2020-09-05.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of 16,16-二甲基前列腺素 E<SUB>2</SUB> in Pharmaceutical Formulations". J. Chromatogr. A, 2011, 817, (5), 8323-8329.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of 16,16-二甲基前列腺素 E<SUB>2</SUB> as an Impurity". Chromatographia, 2014, 1984, 6229-6249.
  3. Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of M790V82VAC 39746-25-3 16,16-Dimethylprostaglandin E2 16,16-Dimethyl prostaglandin E2 Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (5Z,11-alpha,13E,15R)- BRN 2896843 (5Z,11-alpha,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid 7-(2-(4,4-Dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)-5-heptenoic acid 16,16-Dimethyl-pge2 16,16-Dimethyl-prostaglandin E2 5-Heptenoic acid, 7-(2-(4,4-dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)- UNII-M790V82VAC FT1050 Using HRMS and NMR". Anal. Chim. Acta, 2011, 1985, (11), 8372-8393.

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