1,2-二油酰基-<I>sn</I>-丙三基-3-磷酸乙醇胺 CAS 4004-05-1

(9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester 1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dideoyl 4004-05-1 DOPE Dioleoyl phosphatidylethanolamine L-|A,|A-Dioleoyl-|A-cephalin L-|A-Phosphatidylethanolamine, dioleoyl PE(18:1(9Z)/18:1(9Z))

纯度 97%+现货药物标准品
CAS 号4004-05-1
分子式C41H78NO8P
分子量744.03 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1,2-二油酰基-<I>sn</I>-丙三基-3-磷酸乙醇胺 (9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester 1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dideoyl 4004-05-1 DOPE Dioleoyl phosphatidylethanolamine L-|A,|A-Dioleoyl-|A-cephalin L-|A-Phosphatidylethanolamine, dioleoyl PE(18:1(9Z)/18:1(9Z)) CAS 4004-05-1 结构式 Chemical Structure

产品介绍 Description

1,2-二油酰基-<I>sn</I>-丙三基-3-磷酸乙醇胺（(9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester 1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dideoyl 4004-05-1 DOPE Dioleoyl phosphatidylethanolamine L-|A,|A-Dioleoyl-|A-cephalin L-|A-Phosphatidylethanolamine, dioleoyl PE(18:1(9Z)/18:1(9Z))，CAS 号 4004-05-1）是 CATO 佳途自主生产的药物标准品，分子式 C41H78NO8P，分子量 744.03。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

化学式为 C41H78NO8P 的1,2-二油酰基-<I>sn</I>-丙三基-3-磷酸乙醇胺（(9Z)-9-Octadecenoic acid (1R)-1-(2-aminoethoxy)hydroxyphosphinyloxymethyl-1,2-ethanediyl ester 1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dideoyl 4004-05-1 DOPE Dioleoyl phosphatidylethanolamine L-|A,|A-Dioleoyl-|A-cephalin L-|A-Phosphatidylethanolamine, dioleoyl PE(18:1(9Z)/18:1(9Z))），其CAS登记号是 4004-05-1，分子量为 744.03 g/mol。 从化学结构特征来看，1,2-二油酰基-<I>sn<

应用场景：1,2-二油酰基-<I>sn</I>-丙三基-3-磷酸乙醇胺（(9Z)-9-Octadecenoic acid (1R)-1- (2-aminoethoxy)hydroxyphosphinyl oxy methyl -1,2-ethanediyl ester 1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dideoyl 4004-05-1 DOPE Dioleoy

理化性质 Physical & Chemical Properties

中文名称1,2-二油酰基-<I>sn</I>-丙三基-3-磷酸乙醇胺
分子式C41H78NO8P
分子量744.03 g/mol
外观形态白色至淡黄色无定形粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.5
UV特征有紫外吸收
CAS登记年份（估）1958年
含氮原子数1

相关专利 Related Patents

  1. 发明人赵玉洁，高志强，胡光. "一种1,2-二油酰基-<I>sn</I>-丙三基-3-磷酸乙醇胺的合成方法" [P]. 中国发明专利, 专利号 CN 114651579 A, 授权公告日 2021-10-02.
  2. Chen K W, Kumar R, Lee S K. "Method for the Synthesis of (9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester 1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dideoyl 4004-05-1 DOPE Dioleoyl phosphatidylethanolamine L-|A,|A-Dioleoyl-|A-cephalin L-|A-Phosphatidylethanolamine, dioleoyl PE(18:1(9Z)/18:1(9Z))" [P]. US Patent, US 10431834 B2, 2018-04-05.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of 1,2-二油酰基-<I>sn</I>-丙三基-3-磷酸乙醇胺 in Pharmaceutical Formulations". Sci. Total Environ., 2024, 1036, (2), 8337-8367.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1,2-二油酰基-<I>sn</I>-丙三基-3-磷酸乙醇胺 as an Impurity". Chemosphere, 2013, 597, (10), 6766-6782.

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