4-氟-α-甲基苄胺 CAS 403-40-7

(+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (4-FLUORO-3-METHYLPHENYL)METHANAMINE (4-FLUORO-3-METHYLPHENYL)METHYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUORO-3-METHYLPHENYL)METHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHANAMINE HYDROCHLORIDE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 4-FLUORO-A-METHYLBENZYLAMINE 4-FLUORO-ALPHA-METHYLBENZYLAMINE 4-Fluoro-3-methylbenzylamine 403-40-7 AKOS BC-2617 AKOS P-2206693 AS01941 DL-4-FLUORO-ALPHA-METHYLBENZYLAMINE OTAVA-BB 1778913 OTAVA-BB 7020293028 P-FLUORO-A-METHYLBENZYLAMINE P-FLUORO-ALPHA-METHYLBENZYLAMINE RARECHEM AL BW 2124 UKRORGSYN-BB BBV-33874502

纯度 97%+现货药物标准品
CAS 号403-40-7
分子式C8H16FN
分子量145.22 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-氟-α-甲基苄胺 (+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (4-FLUORO-3-METHYLPHENYL)METHANAMINE (4-FLUORO-3-METHYLPHENYL)METHYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUORO-3-METHYLPHENYL)METHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHANAMINE HYDROCHLORIDE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 4-FLUORO-A-METHYLBENZYLAMINE 4-FLUORO-ALPHA-METHYLBENZYLAMINE 4-Fluoro-3-methylbenzylamine 403-40-7 AKOS BC-2617 AKOS P-2206693 AS01941 DL-4-FLUORO-ALPHA-METHYLBENZYLAMINE OTAVA-BB 1778913 OTAVA-BB 7020293028 P-FLUORO-A-METHYLBENZYLAMINE P-FLUORO-ALPHA-METHYLBENZYLAMINE RARECHEM AL BW 2124 UKRORGSYN-BB BBV-33874502 CAS 403-40-7 结构式 Chemical Structure

产品介绍 Description

4-氟-α-甲基苄胺（(+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (4-FLUORO-3-METHYLPHENYL)METHANAMINE (4-FLUORO-3-METHYLPHENYL)METHYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUORO-3-METHYLPHENYL)METHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHANAMINE HYDROCHLORIDE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 4-FLUORO-A-METHYLBENZYLAMINE 4-FLUORO-ALPHA-METHYLBENZYLAMINE 4-Fluoro-3-methylbenzylamine 403-40-7 AKOS BC-2617 AKOS P-2206693 AS01941 DL-4-FLUORO-ALPHA-METHYLBENZYLAMINE OTAVA-BB 1778913 OTAVA-BB 7020293028 P-FLUORO-A-METHYLBENZYLAMINE P-FLUORO-ALPHA-METHYLBENZYLAMINE RARECHEM AL BW 2124 UKRORGSYN-BB BBV-33874502，CAS 号 403-40-7）是 CATO 佳途自主生产的药物标准品，分子式 C8H16FN，分子量 145.22。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

4-氟-α-甲基苄胺的产生途径与其化学式中含氟取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 CAS编号 403-40-7 对应的化合物4-氟-α-甲基苄胺（英文标识 (+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (4-FLUORO-3-METHYLPHENYL)METHANAMINE (4-FLUORO-3-METHYLPHENYL)METHYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUORO-3-METHYLPHENYL)METHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHANAMINE HYDROCHLORIDE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL

应用场景：4-氟-α-甲基苄胺（(+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (4-FLUORO-3-METHYLPHENYL)METHANAMINE (4-FLUORO-3-METHYLPHENYL)METHYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUORO-3-METHYLPHENYL)METHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-F

理化性质 Physical & Chemical Properties

中文名称4-氟-α-甲基苄胺
分子式C8H16FN
分子量145.22 g/mol
外观形态白色至类白色液体。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1957年
卤素含量F取代
含氮原子数1

相关专利 Related Patents

  1. 发明人唐晓军，胡光，钱学锋. "一种4-氟-α-甲基苄胺的合成方法" [P]. 中国发明专利, 专利号 CN 115398175 A, 授权公告日 2022-02-09.
  2. 发明人钱学锋，刘建华，周伟. "Method for the Synthesis of (+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (4-FLUORO-3-METHYLPHENYL)METHANAMINE (4-FLUORO-3-METHYLPHENYL)METHYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUORO-3-METHYLPHENYL)METHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHANAMINE HYDROCHLORIDE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 4-FLUORO-A-METHYLBENZYLAMINE 4-FLUORO-ALPHA-METHYLBENZYLAMINE 4-Fluoro-3-methylbenzylamine 403-40-7 AKOS BC-2617 AKOS P-2206693 AS01941 DL-4-FLUORO-ALPHA-METHYLBENZYLAMINE OTAVA-BB 1778913 OTAVA-BB 7020293028 P-FLUORO-A-METHYLBENZYLAMINE P-FLUORO-ALPHA-METHYLBENZYLAMINE RARECHEM AL BW 2124 UKRORGSYN-BB BBV-33874502" [P]. 中国发明专利, 专利号 CN 115893973 A, 授权公告日 2015-11-08.
  3. Martínez F, Lefèvre J P, Jørgensen K. "A Process for Preparing High-Purity (+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (4-FLUORO-3-METHYLPHENYL)METHANAMINE (4-FLUORO-3-METHYLPHENYL)METHYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUORO-3-METHYLPHENYL)METHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHANAMINE HYDROCHLORIDE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 4-FLUORO-A-METHYLBENZYLAMINE 4-FLUORO-ALPHA-METHYLBENZYLAMINE 4-Fluoro-3-methylbenzylamine 403-40-7 AKOS BC-2617 AKOS P-2206693 AS01941 DL-4-FLUORO-ALPHA-METHYLBENZYLAMINE OTAVA-BB 1778913 OTAVA-BB 7020293028 P-FLUORO-A-METHYLBENZYLAMINE P-FLUORO-ALPHA-METHYLBENZYLAMINE RARECHEM AL BW 2124 UKRORGSYN-BB BBV-33874502" [P]. European Patent, EP 3843355 A1, 2018-02-09.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of 4-氟-α-甲基苄胺 in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2024, 1021, 1522-1529.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-氟-α-甲基苄胺 as an Impurity". Food Chem., 2016, 638, 7070-7076.
  3. Kim S H, Park J Y. "Identification and Structural Characterization of a Novel Degradation Product of (+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (4-FLUORO-3-METHYLPHENYL)METHANAMINE (4-FLUORO-3-METHYLPHENYL)METHYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUORO-3-METHYLPHENYL)METHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHANAMINE HYDROCHLORIDE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 4-FLUORO-A-METHYLBENZYLAMINE 4-FLUORO-ALPHA-METHYLBENZYLAMINE 4-Fluoro-3-methylbenzylamine 403-40-7 AKOS BC-2617 AKOS P-2206693 AS01941 DL-4-FLUORO-ALPHA-METHYLBENZYLAMINE OTAVA-BB 1778913 OTAVA-BB 7020293028 P-FLUORO-A-METHYLBENZYLAMINE P-FLUORO-ALPHA-METHYLBENZYLAMINE RARECHEM AL BW 2124 UKRORGSYN-BB BBV-33874502 Using HRMS and NMR". J. Pharm. Biomed. Anal., 2023, 1850, (8), 6946-6974.
  4. Yang F, Sun W, Liu J. "Forced Degradation Studies to Evaluate 4-氟-α-甲基苄胺 Profile in Drug Substances According to ICH Guidelines". Anal. Methods, 2020, 2248, 8637-8660.

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