1,2-肼基二甲酸二乙酯 CAS 4114-28-7

4114-28-7 Bicarbamic acid, diethyl ester (8CI) Diethyl bicarbamate 1,2-Hydrazinedicarboxylic acid, 1,2-diethyl ester 1,2-Hydrazinedicarboxylic acid, diethyl ester AI3-16138 1,2-Bis(ethoxycarbonyl)hydrazine sym-Dicarbethoxyhydrazine s-Dicarbethoxyhydrazine 1,2-Dicarbethoxyhydrazine N,N'-Diethoxycarbonylhydrazine Diethyl 1,2-hydrazinedicarboxylate Diethyl hydrazodicarboxylate EINECS 223-902-8 Ethyl hydrazoformate NSC 122715 NSC 17295 NSC 227421 NSC 3002

纯度 97%+现货药物标准品
CAS 号4114-28-7
分子式C6H12N2O4
分子量176.17 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1,2-肼基二甲酸二乙酯 4114-28-7 Bicarbamic acid, diethyl ester (8CI) Diethyl bicarbamate 1,2-Hydrazinedicarboxylic acid, 1,2-diethyl ester 1,2-Hydrazinedicarboxylic acid, diethyl ester AI3-16138 1,2-Bis(ethoxycarbonyl)hydrazine sym-Dicarbethoxyhydrazine s-Dicarbethoxyhydrazine 1,2-Dicarbethoxyhydrazine N,N'-Diethoxycarbonylhydrazine Diethyl 1,2-hydrazinedicarboxylate Diethyl hydrazodicarboxylate EINECS 223-902-8 Ethyl hydrazoformate NSC 122715 NSC 17295 NSC 227421 NSC 3002 CAS 4114-28-7 结构式 Chemical Structure

产品介绍 Description

CAS 4114-28-7 对应的1,2-肼基二甲酸二乙酯（4114-28-7 Bicarbamic acid, diethyl ester (8CI) Diethyl bicarbamate 1,2-Hydrazinedicarboxylic acid, 1,2-diethyl ester 1,2-Hydrazinedicarboxylic acid, diethyl ester AI3-16138 1,2-Bis(ethoxycarbonyl)hydrazine sym-Dicarbethoxyhydrazine s-Dicarbethoxyhydrazine 1,2-Dicarbethoxyhydrazine N,N'-Diethoxycarbonylhydrazine Diethyl 1,2-hydrazinedicarboxylate Diethyl hydrazodicarboxylate EINECS 223-902-8 Ethyl hydrazoformate NSC 122715 NSC 17295 NSC 227421 NSC 3002）为 CATO 佳途药物标准品产品线成员。分子式 C6H12N2O4，分子量 176.17。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

与同类药物标准品相比，1,2-肼基二甲酸二乙酯的分子量为176.17 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 4114-28-7 对应的化合物1,2-肼基二甲酸二乙酯（英文标识 4114-28-7 Bicarbamic acid, diethyl ester (8CI) Diethyl bicarbamate 1,2-Hydrazinedicarboxylic acid, 1,2-diethyl ester 1,2-Hydrazinedicarboxylic acid, diethyl ester AI3-16138 1,2-Bis(ethoxycarbonyl)hydrazine sym-Dicarbethoxyhydrazine s-Dicarbethoxyhydrazine 1,2-Dicarbethoxyhydrazine N,N'-Diethoxycarbonylhydrazine Diethyl 1,2-hydrazinedicarboxylate Diethyl hydrazodicarboxylate EINECS 223-9

应用场景：1,2-肼基二甲酸二乙酯（4114-28-7 Bicarbamic acid, diethyl ester (8CI) Diethyl bicarbamate 1,2-Hydrazinedicarboxylic acid, 1,2-diethyl ester 1,2-Hydrazinedicarboxylic acid, diethyl ester AI3-16138 1,2-Bis(ethoxycarbonyl)hydrazine sym-Dicarbethoxyhydrazine s-Dicarbethoxyhydrazine 1,2-Dicarbethoxyhydrazine N,N'-

理化性质 Physical & Chemical Properties

中文名称1,2-肼基二甲酸二乙酯
分子式C6H12N2O4
分子量176.17 g/mol
外观形态白色至类白色结晶性粉末。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1958年
含氮原子数2

相关专利 Related Patents

  1. 发明人高志强，郑宇鹏，朱建伟. "一种1,2-肼基二甲酸二乙酯的合成方法" [P]. 中国发明专利, 专利号 CN 117921663 B, 授权公告日 2025-04-18.
  2. 发明人张德明，马晓峰，徐明华. "Method for the Synthesis of 4114-28-7 Bicarbamic acid, diethyl ester (8CI) Diethyl bicarbamate 1,2-Hydrazinedicarboxylic acid, 1,2-diethyl ester 1,2-Hydrazinedicarboxylic acid, diethyl ester AI3-16138 1,2-Bis(ethoxycarbonyl)hydrazine sym-Dicarbethoxyhydrazine s-Dicarbethoxyhydrazine 1,2-Dicarbethoxyhydrazine N,N'-Diethoxycarbonylhydrazine Diethyl 1,2-hydrazinedicarboxylate Diethyl hydrazodicarboxylate EINECS 223-902-8 Ethyl hydrazoformate NSC 122715 NSC 17295 NSC 227421 NSC 3002" [P]. 中国发明专利, 专利号 CN 116561074 B, 授权公告日 2017-04-01.
  3. Patel M V, Klinger H, Roberts E F. "A Process for Preparing High-Purity 4114-28-7 Bicarbamic acid, diethyl ester (8CI) Diethyl bicarbamate 1,2-Hydrazinedicarboxylic acid, 1,2-diethyl ester 1,2-Hydrazinedicarboxylic acid, diethyl ester AI3-16138 1,2-Bis(ethoxycarbonyl)hydrazine sym-Dicarbethoxyhydrazine s-Dicarbethoxyhydrazine 1,2-Dicarbethoxyhydrazine N,N'-Diethoxycarbonylhydrazine Diethyl 1,2-hydrazinedicarboxylate Diethyl hydrazodicarboxylate EINECS 223-902-8 Ethyl hydrazoformate NSC 122715 NSC 17295 NSC 227421 NSC 3002" [P]. US Patent, US 11001554 B2, 2024-11-06.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of 1,2-肼基二甲酸二乙酯 in Pharmaceutical Formulations". Anal. Methods, 2011, 1337, 691-709.
  2. Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1,2-肼基二甲酸二乙酯 as an Impurity". J. Pharm. Biomed. Anal., 2012, 1573, 2783-2799.

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