6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline CAS 4118-36-9

4118-36-9 1-Phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-phenyl- S-23 6,7-Dimethoxy-4-phenyl-1,2,3,4-tetrahydroisoquinoline

纯度 97%+现货药物标准品
CAS 号4118-36-9
分子式C17H31NO2
分子量281.43 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline 4118-36-9 1-Phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-phenyl- S-23 6,7-Dimethoxy-4-phenyl-1,2,3,4-tetrahydroisoquinoline CAS 4118-36-9 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline（4118-36-9 1-Phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-phenyl- S-23 6,7-Dimethoxy-4-phenyl-1,2,3,4-tetrahydroisoquinoline）为药物标准品，CAS 登记号 4118-36-9，分子式 C17H31NO2，分子量 281.43。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

受分子结构中酰胺类，羧酸类，含羟基，含醚键的影响，6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline表现为白色至淡黄色结晶性粉末。其固体形态的物理化学属性——包括281.43 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。较高的碳氢原子比赋予该化合物良好的脂溶性，可使用正己烷或乙酸乙酯等非极性溶剂进行液-液萃取前处理。 化学式为 C17H31NO2 的6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline（4118-36-9 1-Phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-phenyl- S-23 6,7-Dimethoxy-4-phenyl-1,2,3,4-tetrahydroisoquinoline），其CAS登记号是 4118-36-9，分子量为 281.43 g/mol。 本品适用于

应用场景：6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline（4118-36-9 1-Phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-phenyl- S-23 6,7-Dimethoxy-4-phenyl-1,2,3,4-tetrahydroisoquinoline）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以6,7-Dimethoxy-1-phenyl-1,2,3,4-tetr

理化性质 Physical & Chemical Properties

中文名称6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline
分子式C17H31NO2
分子量281.43 g/mol
外观形态白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1958年
含氮原子数1

相关专利 Related Patents

  1. 发明人马晓峰，孙丽萍，郭海燕. "一种6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline的合成方法" [P]. 中国发明专利, 专利号 CN 113631448 B, 授权公告日 2016-12-24.
  2. 发明人钱学锋，徐明华，郑宇鹏. "Method for the Synthesis of 4118-36-9 1-Phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-phenyl- S-23 6,7-Dimethoxy-4-phenyl-1,2,3,4-tetrahydroisoquinoline" [P]. 中国发明专利, 专利号 CN 117330504 B, 授权公告日 2015-01-18.
  3. Patel M V, Thompson G K, Johnson M A. "A Process for Preparing High-Purity 4118-36-9 1-Phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-phenyl- S-23 6,7-Dimethoxy-4-phenyl-1,2,3,4-tetrahydroisoquinoline" [P]. US Patent, US 9853399 B2, 2017-06-06.

参考文献 Literature

  1. Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of 6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline in Pharmaceutical Formulations". Molecules, 2014, 1489, (6), 7776-7788.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline as an Impurity". Food Chem., 2025, 450, 4752-4757.
  3. Martinez C, Lopez D R. "Identification and Structural Characterization of a Novel Degradation Product of 4118-36-9 1-Phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-phenyl- S-23 6,7-Dimethoxy-4-phenyl-1,2,3,4-tetrahydroisoquinoline Using HRMS and NMR". Rapid Commun. Mass Spectrom., 2021, 1102, (8), 9822-9844.
  4. Mueller T, Schmidt R K. "Forced Degradation Studies to Evaluate 6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2012, 772, (4), 7373-7380.

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