(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione CAS 41722-49-0

(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione

纯度 97%+现货药物标准品
CAS 号41722-49-0
分子式C12H16O2
分子量192.25 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione (S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione CAS 41722-49-0 结构式 Chemical Structure

产品介绍 Description

(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione（英文名 (S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione，CAS 41722-49-0）属于药物标准品。分子式 C12H16O2，分子量 192.25。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione的产生途径与其化学式中羧酸类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 CAS编号 41722-49-0 对应的化合物(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione（英文标识 (S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione），化学式 C12H16O2，相对分子质量 192.25。 从化学结构特征来看，(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione的分子骨架中包含羧酸类，含羟基，含醚键。该化合物的不饱和度为5.0，表明结构中存在约5个环或双键等价单元。分子量为192.25 g/mol，属于中等分子量化合物。分子中包含芳环或共轭体系，在UV-Vis光谱中具有特征性吸收

应用场景：(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione（(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： -

理化性质 Physical & Chemical Properties

中文名称(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione
分子式C12H16O2
分子量192.25 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性空气中长期暴露可能发生缓慢氧化
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1968年

相关专利 Related Patents

  1. Klinger H, Brown S R, Patel M V. "一种(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione的合成方法" [P]. US Patent, US 10978223 B2, 2017-11-22.
  2. 发明人沈红梅，王建平，何建平. "Method for the Synthesis of (S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione" [P]. 中国发明专利, 专利号 CN 108881806 A, 授权公告日 2016-10-02.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of (S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione in Pharmaceutical Formulations". Molecules, 2010, 2476, (7), 6186-6202.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of (S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione as an Impurity". Sci. Total Environ., 2015, 2420, (9), 5523-5530.
  3. Brown R C, Davis S M. "Identification and Structural Characterization of a Novel Degradation Product of (S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione Using HRMS and NMR". Phytochemistry, 2019, 1274, 946-970.
  4. Lee J H, Choi Y S. "Forced Degradation Studies to Evaluate (S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione Profile in Drug Substances According to ICH Guidelines". Anal. Chim. Acta, 2016, 1708, 9349-9379.

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...