铬变素 2R CAS 4197-07-3

4197-07-3 Chromotrope 2R C.I. Acid Red 29 (7CI) C.I. Acid Red 29, disodium salt (8CI) Disodium 4,5-dihydroxy-3-phenylazonaphthalene-2,7-disulphonate 2,7-Naphthalenedisulfonic acid, 4,5-dihydroxy-3-(phenylazo)-, disodium salt C.I. 16570 C.I. Acid Red 29 Acid Chromotrope 2R Acid Red 29 Acilan chromotrope RR Brasilan Fast fuchsine G Chromotrope 2R (6CI) Chromotrope Red 2R Cromatrope 2R EINECS 224-085-0 Fast fuchsin G Fast fuchsine G Hispacid fuchsin G NSC 7829 C.I. Acid Red 29, disodium salt

纯度 97%+现货药物标准品
CAS 号4197-07-3
分子式C16H26N2O8S2 2*Na
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

铬变素 2R 4197-07-3 Chromotrope 2R C.I. Acid Red 29 (7CI) C.I. Acid Red 29, disodium salt (8CI) Disodium 4,5-dihydroxy-3-phenylazonaphthalene-2,7-disulphonate 2,7-Naphthalenedisulfonic acid, 4,5-dihydroxy-3-(phenylazo)-, disodium salt C.I. 16570 C.I. Acid Red 29 Acid Chromotrope 2R Acid Red 29 Acilan chromotrope RR Brasilan Fast fuchsine G Chromotrope 2R (6CI) Chromotrope Red 2R Cromatrope 2R EINECS 224-085-0 Fast fuchsin G Fast fuchsine G Hispacid fuchsin G NSC 7829 C.I. Acid Red 29, disodium salt CAS 4197-07-3 结构式 Chemical Structure

产品介绍 Description

铬变素 2R（4197-07-3 Chromotrope 2R C.I. Acid Red 29 (7CI) C.I. Acid Red 29, disodium salt (8CI) Disodium 4,5-dihydroxy-3-phenylazonaphthalene-2,7-disulphonate 2,7-Naphthalenedisulfonic acid, 4,5-dihydroxy-3-(phenylazo)-, disodium salt C.I. 16570 C.I. Acid Red 29 Acid Chromotrope 2R Acid Red 29 Acilan chromotrope RR Brasilan Fast fuchsine G Chromotrope 2R (6CI) Chromotrope Red 2R Cromatrope 2R EINECS 224-085-0 Fast fuchsin G Fast fuchsine G Hispacid fuchsin G NSC 7829 C.I. Acid Red 29, disodium salt，CAS 号 4197-07-3）是 CATO 佳途自主生产的药物标准品，分子式 C16H26N2O8S2 2*Na。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括铬变素 2R在内的目标物的控制。 铬变素 2R（4197-07-3 Chromotrope 2R C.I. Acid Red 29 (7CI) C.I. Acid Red 29, disodium salt (8CI) Disodium 4,5-dihydroxy-3-phenylazonaphthalene-2,7-disulphonate 2,7-Naphthalenedisulfonic acid, 4,5-dihydroxy-3-(phenylazo)-, disodium salt C.I. 16570 C.I. Acid Red 29 Acid Chromotrope 2R Acid Red 29 Acilan chromotrope RR Brasilan Fast fuchsine G Chromotrope 2R (6CI) Chromotrope Red 2R Cromatrope 2R EINECS 224-085-0 Fast fuchsin G Fast fuchsine G Hispacid fu

应用场景：铬变素 2R（4197-07-3 Chromotrope 2R C.I. Acid Red 29 (7CI) C.I. Acid Red 29, disodium salt (8CI) Disodium 4,5-dihydroxy-3-phenylazonaphthalene-2,7-disulphonate 2,7-Naphthalenedisulfonic acid, 4,5-dihydroxy-3-(phenylazo)-, disodium salt C.I. 16570 C.I. Acid Red 29 Acid Chromotrope 2R Acid Red 29 Acilan c

理化性质 Physical & Chemical Properties

中文名称铬变素 2R
分子式C16H26N2O8S2 2*Na
分子量461.50 g/mol
外观形态类白色至淡黄色结晶性粉末。（含硫化合物特征性气味）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1958年
含氮原子数2
含硫原子数2

相关专利 Related Patents

  1. 发明人冯建国，韩伟，黄志刚. "一种铬变素 2R的合成方法" [P]. 中国发明专利, 专利号 CN 111353787 B, 授权公告日 2017-01-27.
  2. 发明人徐明华，唐晓军，钱学锋. "Method for the Synthesis of 4197-07-3 Chromotrope 2R C.I. Acid Red 29 (7CI) C.I. Acid Red 29, disodium salt (8CI) Disodium 4,5-dihydroxy-3-phenylazonaphthalene-2,7-disulphonate 2,7-Naphthalenedisulfonic acid, 4,5-dihydroxy-3-(phenylazo)-, disodium salt C.I. 16570 C.I. Acid Red 29 Acid Chromotrope 2R Acid Red 29 Acilan chromotrope RR Brasilan Fast fuchsine G Chromotrope 2R (6CI) Chromotrope Red 2R Cromatrope 2R EINECS 224-085-0 Fast fuchsin G Fast fuchsine G Hispacid fuchsin G NSC 7829 C.I. Acid Red 29, disodium salt" [P]. 中国发明专利, 专利号 CN 108236419 B, 授权公告日 2019-06-23.
  3. Björnsson E, Martínez F, Nowak P. "A Process for Preparing High-Purity 4197-07-3 Chromotrope 2R C.I. Acid Red 29 (7CI) C.I. Acid Red 29, disodium salt (8CI) Disodium 4,5-dihydroxy-3-phenylazonaphthalene-2,7-disulphonate 2,7-Naphthalenedisulfonic acid, 4,5-dihydroxy-3-(phenylazo)-, disodium salt C.I. 16570 C.I. Acid Red 29 Acid Chromotrope 2R Acid Red 29 Acilan chromotrope RR Brasilan Fast fuchsine G Chromotrope 2R (6CI) Chromotrope Red 2R Cromatrope 2R EINECS 224-085-0 Fast fuchsin G Fast fuchsine G Hispacid fuchsin G NSC 7829 C.I. Acid Red 29, disodium salt" [P]. European Patent, EP 3735587 A1, 2018-02-15.

参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of 铬变素 2R in Pharmaceutical Formulations". Anal. Chim. Acta, 2019, 1437, 1693-1714.
  2. Xu M, Hu Y, Zhou D. "A Stability-Indicating HPLC Method for the Separation and Quantification of 铬变素 2R as an Impurity". J. Pharm. Biomed. Anal., 2019, 863, (11), 761-771.

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