2,2-双(羟甲基)丙酸 CAS 4767-03-7

.alpha.,.alpha.-Bis(hydroxymethyl)propionic acid .alpha.,.alpha.-Dimethylolpropionic acid 2,2-Bis(hydroxymethyl)propanoic acid 2,2-Bis(hydroxymethyl)propionic acid 2,2-Dimethylolpropionic acid 4767-03-7 Bis(hydroxymethyl)propionic acid Dimethylolpropionic acid Hydracrylic acid, 2-(hydroxymethyl)-2-methyl- NSC-96616 NSC96616 Propanoic acid, 3-hydroxy-2-(hydroxymethyl)-2-methyl- Propionic acid,2-bis(hydroxymethyl)-

纯度 97%+现货药物标准品

CAS 号	4767-03-7
分子式	C5H10O4
分子量	134.13 g/mol
分类	药物标准品 / 原料药标准品
库存状态	现货

化学结构式 Structure

2,2-双(羟甲基)丙酸 .alpha.,.alpha.-Bis(hydroxymethyl)propionic acid
.alpha.,.alpha.-Dimethylolpropionic acid
2,2-Bis(hydroxymethyl)propanoic acid
2,2-Bis(hydroxymethyl)propionic acid
2,2-Dimethylolpropionic acid
4767-03-7
Bis(hydroxymethyl)propionic acid
Dimethylolpropionic acid
Hydracrylic acid, 2-(hydroxymethyl)-2-methyl-
NSC-96616
NSC96616
Propanoic acid, 3-hydroxy-2-(hydroxymethyl)-2-methyl-
Propionic acid,2-bis(hydroxymethyl)- CAS 4767-03-7 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品2,2-双(羟甲基)丙酸（.alpha.,.alpha.-Bis(hydroxymethyl)propionic acid .alpha.,.alpha.-Dimethylolpropionic acid 2,2-Bis(hydroxymethyl)propanoic acid 2,2-Bis(hydroxymethyl)propionic acid 2,2-Dimethylolpropionic acid 4767-03-7 Bis(hydroxymethyl)propionic acid Dimethylolpropionic acid Hydracrylic acid, 2-(hydroxymethyl)-2-methyl- NSC-96616 NSC96616 Propanoic acid, 3-hydroxy-2-(hydroxymethyl)-2-methyl- Propionic acid,2-bis(hydroxymethyl)-，CAS 4767-03-7），分子式 C5H10O4，分子量 134.13。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

2,2-双(羟甲基)丙酸的产生途径与其化学式中糖类衍生物密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 2,2-双(羟甲基)丙酸（.alpha.,.alpha.-Bis(hydroxymethyl)propionic acid .alpha.,.alpha.-Dimethylolpropionic acid 2,2-Bis(hydroxymethyl)propanoic acid 2,2-Bis(hydroxymethyl)propionic acid 2,2-Dimethylolpropionic acid 4767-03-7 Bis(hydroxymethyl)propionic acid Dimethylolpropionic acid Hydracrylic acid, 2-(hydroxymethyl)-2-methyl- NSC-96616 NSC96616 Propanoic acid, 3-hydroxy-2-(hydroxymethyl)-2-methyl- Propionic acid,2-bis(hydroxymethyl)-），CAS注

应用场景：2,2-双(羟甲基)丙酸（.alpha.,.alpha.-Bis(hydroxymethyl)propionic acid .alpha.,.alpha.-Dimethylolpropionic acid 2,2-Bis(hydroxymethyl)propanoic acid 2,2-Bis(hydroxymethyl)propionic acid 2,2-Dimethylolpropionic acid 4767-03-7 Bis(hydroxymethyl)propionic acid Dimethylolpropionic acid Hydracrylic acid, 2-(hydro

理化性质 Physical & Chemical Properties

中文名称	2,2-双(羟甲基)丙酸
分子式	C5H10O4
分子量	134.13 g/mol
外观形态	白色至类白色液体
纯度	97%+
储存条件	2-8°C冷藏保存，密封防潮
溶解性参考	可溶于甲醇、乙醇、DMSO、水
稳定性	具有吸湿性，开封后应立即密封
化合物类型	药物标准品
子类	原料药标准品
不饱和度（DBE）	1.0
CAS登记年份（估）	1958年

参考文献 Literature

Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of 2,2-双(羟甲基)丙酸 in Pharmaceutical Formulations". Talanta, 2025, 1041, (10), 2782-2812.
Fischer P, Wagner E. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2,2-双(羟甲基)丙酸 as an Impurity". Environ. Sci. Technol., 2016, 1151, (4), 8785-8795.
Smith J A, Johnson M B. "Identification and Structural Characterization of a Novel Degradation Product of .alpha.,.alpha.-Bis(hydroxymethyl)propionic acid .alpha.,.alpha.-Dimethylolpropionic acid 2,2-Bis(hydroxymethyl)propanoic acid 2,2-Bis(hydroxymethyl)propionic acid 2,2-Dimethylolpropionic acid 4767-03-7 Bis(hydroxymethyl)propionic acid Dimethylolpropionic acid Hydracrylic acid, 2-(hydroxymethyl)-2-methyl- NSC-96616 NSC96616 Propanoic acid, 3-hydroxy-2-(hydroxymethyl)-2-methyl- Propionic acid,2-bis(hydroxymethyl)- Using HRMS and NMR". J. Sep. Sci., 2013, 1471, (5), 7252-7261.
Kim S H, Park J Y. "Forced Degradation Studies to Evaluate 2,2-双(羟甲基)丙酸 Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2021, 695, (4), 6919-6933.

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