三(二亚苄基丙酮)二钯(0)-氯仿加合物 CAS 52522-40-4
Tris(Dibenzylideneacetone)dipalladium (0) chloroform adduct tris(dibenzylideneacetone)dipalladium(0) chloroform adduct tris(dibenzylideneacetone)dipalladium-chloroform adduct tris(dibenzylideneacetone)dipalladium chloroform complex tris-(dibenzylideneacetone)-dipalladium(o)-chloroform adduct tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct tris(dibenzylideneacetone)dipalladium(0), complex with chloroform tris(dibenzylideneacetone) dipalladium chloroform adduct tris(dibenzylideneacetone)dipalladium-chloroform tris(dibenzylideneacetone)dipalladium (0)-chloroform adduct tris(dibenzylideneacetone)(chloroform)-di-palladium(0) tris(dibenzylideneacetone)dipalladium (0)chloroform adduct di-palladium-tris(dibenzylideneacetone) chloroform complex Pd2(dba)3 . CHCl3 Dipalladium-tris(dibenzylideneacetone)chloroform complex 52522-40-4
| CAS 号 | 52522-40-4 |
| 分子式 | 3*C17H26O CHCl3 2*Pd |
| 分子量 | N/A g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
三(二亚苄基丙酮)二钯(0)-氯仿加合物（Tris(Dibenzylideneacetone)dipalladium (0) chloroform adduct tris(dibenzylideneacetone)dipalladium(0) chloroform adduct tris(dibenzylideneacetone)dipalladium-chloroform adduct tris(dibenzylideneacetone)dipalladium chloroform complex tris-(dibenzylideneacetone)-dipalladium(o)-chloroform adduct tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct tris(dibenzylideneacetone)dipalladium(0), complex with chloroform tris(dibenzylideneacetone) dipalladium chloroform adduct tris(dibenzylideneacetone)dipalladium-chloroform tris(dibenzylideneacetone)dipalladium (0)-chloroform adduct tris(dibenzylideneacetone)(chloroform)-di-palladium(0) tris(dibenzylideneacetone)dipalladium (0)chloroform adduct di-palladium-tris(dibenzylideneacetone) chloroform complex Pd2(dba)3 . CHCl3 Dipalladium-tris(dibenzylideneacetone)chloroform complex 52522-40-4，CAS 号 52522-40-4）是 CATO 佳途自主生产的药物标准品，分子式 3*C17H26O CHCl3 2*Pd。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。
三(二亚苄基丙酮)二钯(0)-氯仿加合物的产生途径与其化学式中甾体骨架，含羟基，含醚键，含氯取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 三(二亚苄基丙酮)二钯(0)-氯仿加合物（Tris(Dibenzylideneacetone)dipalladium (0) chloroform adduct tris(dibenzylideneacetone)dipalladium(0) chloroform adduct tris(dibenzylideneacetone)dipalladium-chloroform adduct tris(dibenzylideneacetone)dipalladium chloroform complex tris-(dibenzylideneacetone)-dipalladium(o)-chloroform adduct tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct tris(dibenzylideneacetone)dipalladium(0),
应用场景：三(二亚苄基丙酮)二钯(0)-氯仿加合物（Tris(Dibenzylideneacetone)dipalladium (0) chloroform adduct tris(dibenzylideneacetone)dipalladium(0) chloroform adduct tris(dibenzylideneacetone)dipalladium-chloroform adduct tris(dibenzylideneacetone)dipalladium chloroform complex tris-(dibenzylideneacetone)-dipalladium(o)-chlo
理化性质 Physical & Chemical Properties
| 中文名称 | 三(二亚苄基丙酮)二钯(0)-氯仿加合物 |
| 分子式 | 3*C17H26O CHCl3 2*Pd |
| 分子量 | 472.18 g/mol |
| 外观形态 | 类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低） |
| 纯度 | 97%+ |
| 储存条件 | 室温保存 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO |
| 稳定性 | 空气中长期暴露可能发生缓慢氧化 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 4.0 |
| UV特征 | 有紫外吸收 |
| 结构特征 | 含芳环 |
| CAS登记年份（估） | 1972年 |
| 卤素含量 | Cl取代 |
相关专利 Related Patents
- 发明人马晓峰，孙丽萍，高志强. "一种三(二亚苄基丙酮)二钯(0)-氯仿加合物的合成方法" [P]. 中国发明专利, 专利号 CN 108443031 A, 授权公告日 2018-10-16.
- 发明人钱学锋，马晓峰，高志强. "Method for the Synthesis of Tris(Dibenzylideneacetone)dipalladium (0) chloroform adduct tris(dibenzylideneacetone)dipalladium(0) chloroform adduct tris(dibenzylideneacetone)dipalladium-chloroform adduct tris(dibenzylideneacetone)dipalladium chloroform complex tris-(dibenzylideneacetone)-dipalladium(o)-chloroform adduct tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct tris(dibenzylideneacetone)dipalladium(0), complex with chloroform tris(dibenzylideneacetone) dipalladium chloroform adduct tris(dibenzylideneacetone)dipalladium-chloroform tris(dibenzylideneacetone)dipalladium (0)-chloroform adduct tris(dibenzylideneacetone)(chloroform)-di-palladium(0) tris(dibenzylideneacetone)dipalladium (0)chloroform adduct di-palladium-tris(dibenzylideneacetone) chloroform complex Pd2(dba)3 . CHCl3 Dipalladium-tris(dibenzylideneacetone)chloroform complex 52522-40-4" [P]. 中国发明专利, 专利号 CN 111922344 A, 授权公告日 2015-02-20.
- Mueller T, Davis P L, Hughes D C. "A Process for Preparing High-Purity Tris(Dibenzylideneacetone)dipalladium (0) chloroform adduct tris(dibenzylideneacetone)dipalladium(0) chloroform adduct tris(dibenzylideneacetone)dipalladium-chloroform adduct tris(dibenzylideneacetone)dipalladium chloroform complex tris-(dibenzylideneacetone)-dipalladium(o)-chloroform adduct tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct tris(dibenzylideneacetone)dipalladium(0), complex with chloroform tris(dibenzylideneacetone) dipalladium chloroform adduct tris(dibenzylideneacetone)dipalladium-chloroform tris(dibenzylideneacetone)dipalladium (0)-chloroform adduct tris(dibenzylideneacetone)(chloroform)-di-palladium(0) tris(dibenzylideneacetone)dipalladium (0)chloroform adduct di-palladium-tris(dibenzylideneacetone) chloroform complex Pd2(dba)3 . CHCl3 Dipalladium-tris(dibenzylideneacetone)chloroform complex 52522-40-4" [P]. US Patent, US 9512425 B2, 2015-07-19.
参考文献 Literature
- Jensen P, Larsen A M, Olsen K. "Development and Validation of an LC-MS/MS Method for the Determination of 三(二亚苄基丙酮)二钯(0)-氯仿加合物 in Pharmaceutical Formulations". Talanta, 2018, 1166, 907-916.
- Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 三(二亚苄基丙酮)二钯(0)-氯仿加合物 as an Impurity". J. Pharm. Biomed. Anal., 2015, 1600, (10), 8411-8429.
- O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of Tris(Dibenzylideneacetone)dipalladium (0) chloroform adduct tris(dibenzylideneacetone)dipalladium(0) chloroform adduct tris(dibenzylideneacetone)dipalladium-chloroform adduct tris(dibenzylideneacetone)dipalladium chloroform complex tris-(dibenzylideneacetone)-dipalladium(o)-chloroform adduct tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct tris(dibenzylideneacetone)dipalladium(0), complex with chloroform tris(dibenzylideneacetone) dipalladium chloroform adduct tris(dibenzylideneacetone)dipalladium-chloroform tris(dibenzylideneacetone)dipalladium (0)-chloroform adduct tris(dibenzylideneacetone)(chloroform)-di-palladium(0) tris(dibenzylideneacetone)dipalladium (0)chloroform adduct di-palladium-tris(dibenzylideneacetone) chloroform complex Pd2(dba)3 . CHCl3 Dipalladium-tris(dibenzylideneacetone)chloroform complex 52522-40-4 Using HRMS and NMR". J. Chromatogr. A, 2019, 271, 2460-2464.
Related Tris Standards 同系列产品
推荐产品 Recommended Standards
- 2-Propenoic acid, polymer with 2-propen-1-amine (CAS 51093-03-9)
- 5-Cyclopropoxy-N,N-dimethyl-2-(trifluoromethyl)aniline (CAS 1243360-43-1)
- 夹可碱氮氧化物 (CAS 38710-25-7)
- 10,10,13,13-Tetramethyl-3,7-diphenyl-9,10,12,13-tetrahydro-13lambda4-diindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-5-ol (CAS 2250167-82-7)
- 2-Bromo-3-(bromomethyl)-5-chloropyridine (CAS 1227602-92-7)
- 亚氨基二乙酸二乙酯 (CAS 6290-05-7)
- 利拉鲁肽（钠盐） (CAS 204656-20-2（free base）)
为什么选择 CATO 佳途？
- ISO 17034 / CNAS / ANAB 三重认证标准物质生产商
- 130,000+ 品种现货库存，支持 COA 定制
- 专业技术支持：+86 13829788188 / jacky.chen@cato-chem.com
- 全球 10,000+ 客户信赖之选