4-吗啉哌啶 CAS 53617-35-9

4-(Piperidin-4-yl)-morpholine 4-morpholino piperidine 4-piperidin-4-yl-morpholine 4-(piperidin-4-yl)morpholine 4-piperidin-4-ylmorpholine morpholine, 4-(4-piperidinyl)- 4-Morpholinopiperidine 4-(4-Piperidinyl) morpholine 53617-35-9

纯度 97%+现货药物标准品
CAS 号53617-35-9
分子式C9H18N2O
分子量170.25 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-吗啉哌啶 4-(Piperidin-4-yl)-morpholine 4-morpholino piperidine 4-piperidin-4-yl-morpholine 4-(piperidin-4-yl)morpholine 4-piperidin-4-ylmorpholine morpholine, 4-(4-piperidinyl)- 4-Morpholinopiperidine 4-(4-Piperidinyl) morpholine 53617-35-9 CAS 53617-35-9 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的4-吗啉哌啶（4-(Piperidin-4-yl)-morpholine 4-morpholino piperidine 4-piperidin-4-yl-morpholine 4-(piperidin-4-yl)morpholine 4-piperidin-4-ylmorpholine morpholine, 4-(4-piperidinyl)- 4-Morpholinopiperidine 4-(4-Piperidinyl) morpholine 53617-35-9）为药物标准品，CAS 登记号 53617-35-9，分子式 C9H18N2O，分子量 170.25。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

从化学结构特征来看，4-吗啉哌啶的分子骨架中包含酰胺类，含羟基，含醚键。该化合物的不饱和度为2.0，表明结构中存在约2个环或双键等价单元。分子量为170.25 g/mol，属于中等分子量化合物。含氮官能团的存在使该化合物在ESI正离子模式下具有优良的离子化效率，适合LC-MS/MS分析。 化学式为 C9H18N2O 的4-吗啉哌啶（4-(Piperidin-4-yl)-morpholine 4-morpholino piperidine 4-piperidin-4-yl-morpholine 4-(piperidin-4-yl)morpholine 4-piperidin-4-ylmorpholine morpholine, 4-(4-piperidinyl)- 4-Morpholinopiperidine 4-(4-Piperidinyl) morpholine 53617-35-9），其CAS登记号是 53617-35-9，分子量为 170.25 g/mol。 在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS, F

应用场景：针对化学分析用途，4-吗啉哌啶（4-(Piperidin-4-yl)-morpholine 4-morpholino piperidine 4-piperidin-4-yl-morpholine 4-(piperidin-4-yl)morpholine 4-piperidin-4-ylmorpholine morpholine, 4-(4-piperidinyl)- 4-Morpholinopiperidine 4-(4-Piperidinyl) morpholine 53617-35-9）是具有明确定量溯源的认证级对照品。 推荐以4-吗啉哌啶配制标准系列工作溶液，用于建立标准曲线实现外标法

理化性质 Physical & Chemical Properties

中文名称4-吗啉哌啶
分子式C9H18N2O
分子量170.25 g/mol
外观形态白色至类白色结晶性粉末。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1972年
含氮原子数2

相关专利 Related Patents

  1. 发明人张德明，郑宇鹏，周伟. "一种4-吗啉哌啶的合成方法" [P]. 中国发明专利, 专利号 CN 113757727 A, 授权公告日 2021-01-12.
  2. 发明人郭海燕，郑宇鹏，陈志强. "Method for the Synthesis of 4-(Piperidin-4-yl)-morpholine 4-morpholino piperidine 4-piperidin-4-yl-morpholine 4-(piperidin-4-yl)morpholine 4-piperidin-4-ylmorpholine morpholine, 4-(4-piperidinyl)- 4-Morpholinopiperidine 4-(4-Piperidinyl) morpholine 53617-35-9" [P]. 中国发明专利, 专利号 CN 112198862 A, 授权公告日 2023-03-18.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of 4-吗啉哌啶 in Pharmaceutical Formulations". Anal. Chem., 2015, 722, (10), 3414-3441.
  2. Jensen P, Larsen A M, Olsen K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-吗啉哌啶 as an Impurity". Food Chem., 2013, 894, 2294-2315.
  3. Zhang Y, Li Q, Chen T. "Identification and Structural Characterization of a Novel Degradation Product of 4-(Piperidin-4-yl)-morpholine 4-morpholino piperidine 4-piperidin-4-yl-morpholine 4-(piperidin-4-yl)morpholine 4-piperidin-4-ylmorpholine morpholine, 4-(4-piperidinyl)- 4-Morpholinopiperidine 4-(4-Piperidinyl) morpholine 53617-35-9 Using HRMS and NMR". Talanta, 2012, 978, 9467-9493.
  4. Wang L, Li J, Zhang H. "Forced Degradation Studies to Evaluate 4-吗啉哌啶 Profile in Drug Substances According to ICH Guidelines". Molecules, 2024, 1491, (1), 9835-9847.

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