(1-Benzyl-1<I>H</I>-imidazol-2-yl)methanol CAS 5376-10-3

1-Benzyl-2-(hydroxymethyl)imidazole (1-benzyl-1h-imidazol-2-yl)methanol (1-benzyl-1h-imidazol-2-yl)-methanol 1-benzyl-2-hydroxymethylimidazole 1-benzyl-2-(hydroxymethyl)-1h-imidazole 1-benzyl-2-hydroxymethyl imidazole 5376-10-3

纯度 97%+现货药物标准品
CAS 号5376-10-3
分子式C11H22N2O
分子量198.31 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(1-Benzyl-1<I>H</I>-imidazol-2-yl)methanol 1-Benzyl-2-(hydroxymethyl)imidazole (1-benzyl-1h-imidazol-2-yl)methanol (1-benzyl-1h-imidazol-2-yl)-methanol 1-benzyl-2-hydroxymethylimidazole 1-benzyl-2-(hydroxymethyl)-1h-imidazole 1-benzyl-2-hydroxymethyl imidazole 5376-10-3 CAS 5376-10-3 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品(1-Benzyl-1<I>H</I>-imidazol-2-yl)methanol（1-Benzyl-2-(hydroxymethyl)imidazole (1-benzyl-1h-imidazol-2-yl)methanol (1-benzyl-1h-imidazol-2-yl)-methanol 1-benzyl-2-hydroxymethylimidazole 1-benzyl-2-(hydroxymethyl)-1h-imidazole 1-benzyl-2-hydroxymethyl imidazole 5376-10-3，CAS 5376-10-3），分子式 C11H22N2O，分子量 198.31。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

与同类药物标准品相比，(1-Benzyl-1<I>H</I>-imidazol-2-yl)methanol的分子量为198.31 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C11H22N2O 的(1-Benzyl-1<I>H</I>-imidazol-2-yl)methanol（1-Benzyl-2-(hydroxymethyl)imidazole (1-benzyl-1h-imidazol-2-yl)methanol (1-benzyl-1h-imidazol-2-yl)-methanol 1-benzyl-2-hydroxymethylimidazole 1-benzyl-2-(hydroxymethyl)-1h-imidazole 1-benzyl-2-hydroxymethyl imidazole 5376-10-3），其CAS登记号是 5376-10-3，分子量为 198.31 g/mol。 依据分子式为 C11H22N2O 的(1-Benzyl-1<I>H</I>-imidazol-2-yl)methanol结构特征，其分子内含酰胺

应用场景：针对化学分析用途，(1-Benzyl-1<I>H</I>-imidazol-2-yl)methanol（1-Benzyl-2-(hydroxymethyl)imidazole (1-benzyl-1h-imidazol-2-yl)methanol (1-benzyl-1h-imidazol-2-yl)-methanol 1-benzyl-2-hydroxymethylimidazole 1-benzyl-2-(hydroxymethyl)-1h-imidazole 1-benzyl-2-hydroxymethyl imidazole 5376-10-3）是具有明确定量溯源的认证级对照品。 推

理化性质 Physical & Chemical Properties

中文名称(1-Benzyl-1<I>H</I>-imidazol-2-yl)methanol
分子式C11H22N2O
分子量198.31 g/mol
外观形态白色至类白色低熔点固体
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1958年
含氮原子数2

相关专利 Related Patents

  1. 发明人黄志刚，胡光，杨光. "一种(1-Benzyl-1<I>H</I>-imidazol-2-yl)methanol的合成方法" [P]. 中国发明专利, 专利号 CN 112574893 B, 授权公告日 2020-12-18.
  2. Björnsson E, Lefèvre J P, Jørgensen K. "Method for the Synthesis of 1-Benzyl-2-(hydroxymethyl)imidazole (1-benzyl-1h-imidazol-2-yl)methanol (1-benzyl-1h-imidazol-2-yl)-methanol 1-benzyl-2-hydroxymethylimidazole 1-benzyl-2-(hydroxymethyl)-1h-imidazole 1-benzyl-2-hydroxymethyl imidazole 5376-10-3" [P]. European Patent, EP 3354648 A1, 2017-08-11.
  3. Anderson J P, Williams B T, Stevens L M. "A Process for Preparing High-Purity 1-Benzyl-2-(hydroxymethyl)imidazole (1-benzyl-1h-imidazol-2-yl)methanol (1-benzyl-1h-imidazol-2-yl)-methanol 1-benzyl-2-hydroxymethylimidazole 1-benzyl-2-(hydroxymethyl)-1h-imidazole 1-benzyl-2-hydroxymethyl imidazole 5376-10-3" [P]. US Patent, US 11695022 B2, 2022-01-09.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of (1-Benzyl-1<I>H</I>-imidazol-2-yl)methanol in Pharmaceutical Formulations". Anal. Methods, 2012, 424, (11), 9355-9367.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of (1-Benzyl-1<I>H</I>-imidazol-2-yl)methanol as an Impurity". J. Chromatogr. A, 2020, 1057, (1), 8394-8413.
  3. Kowalski T, Nowak Z. "Identification and Structural Characterization of a Novel Degradation Product of 1-Benzyl-2-(hydroxymethyl)imidazole (1-benzyl-1h-imidazol-2-yl)methanol (1-benzyl-1h-imidazol-2-yl)-methanol 1-benzyl-2-hydroxymethylimidazole 1-benzyl-2-(hydroxymethyl)-1h-imidazole 1-benzyl-2-hydroxymethyl imidazole 5376-10-3 Using HRMS and NMR". Food Chem., 2023, 630, 1248-1273.

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