伊红 B CAS 548-24-3

548-24-3 OMS4XQD1T0 Eosine I Bluish Eosin B 2-(4,5-Dibromo-3,6-dihydroxy-2,7-dinitroxanthen-9-yl)-benzoic acid, disodium salt Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, sodium salt (1:2) Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, disodium salt AI3-63053 EINECS 208-943-1 C.I. 45400 C.I. Acid Red 91 Dibromodinitrofluorescein sodium Eosin BA Eosine B Eosine BA Eosine BN Eosine BNX Saffrosine UNII-OMS4XQD1T0

纯度 97%+现货药物标准品
CAS 号548-24-3
分子式C20H18Br2N2O9 2*Na
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

伊红 B 548-24-3 OMS4XQD1T0 Eosine I Bluish Eosin B 2-(4,5-Dibromo-3,6-dihydroxy-2,7-dinitroxanthen-9-yl)-benzoic acid, disodium salt Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, sodium salt (1:2) Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, disodium salt AI3-63053 EINECS 208-943-1 C.I. 45400 C.I. Acid Red 91 Dibromodinitrofluorescein sodium Eosin BA Eosine B Eosine BA Eosine BN Eosine BNX Saffrosine UNII-OMS4XQD1T0 CAS 548-24-3 结构式 Chemical Structure

产品介绍 Description

伊红 B（548-24-3 OMS4XQD1T0 Eosine I Bluish Eosin B 2-(4,5-Dibromo-3,6-dihydroxy-2,7-dinitroxanthen-9-yl)-benzoic acid, disodium salt Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, sodium salt (1:2) Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, disodium salt AI3-63053 EINECS 208-943-1 C.I. 45400 C.I. Acid Red 91 Dibromodinitrofluorescein sodium Eosin BA Eosine B Eosine BA Eosine BN Eosine BNX Saffrosine UNII-OMS4XQD1T0，CAS 号 548-24-3）是 CATO 佳途自主生产的药物标准品，分子式 C20H18Br2N2O9 2*Na。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

作为认证标准物质（CRM），伊红 B满足CNAS-CL04（ISO/IEC 17025）对标准物质的计量溯源性要求。批间一致性通过控制图（Control Chart）进行持续监控，保证不同批次间量值的一致性。 CAS编号 548-24-3 对应的化合物伊红 B（英文标识 548-24-3 OMS4XQD1T0 Eosine I Bluish Eosin B 2-(4,5-Dibromo-3,6-dihydroxy-2,7-dinitroxanthen-9-yl)-benzoic acid, disodium salt Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, sodium salt (1:2) Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, disodium salt AI3-630

应用场景：伊红 B（548-24-3 OMS4XQD1T0 Eosine I Bluish Eosin B 2-(4,5-Dibromo-3,6-dihydroxy-2,7-dinitroxanthen-9-yl)-benzoic acid, disodium salt Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, sodium salt (1:2) Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-d

理化性质 Physical & Chemical Properties

中文名称伊红 B
分子式C20H18Br2N2O9 2*Na
分子量613.17 g/mol
外观形态淡黄色至黄色无定形粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）12.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1957年
卤素含量Br取代
含氮原子数2

相关专利 Related Patents

  1. 发明人刘建华，杨光，钱学锋. "一种伊红 B的合成方法" [P]. 中国发明专利, 专利号 CN 108395792 B, 授权公告日 2016-12-26.
  2. 发明人王建平，陈志强，冯建国. "Method for the Synthesis of 548-24-3 OMS4XQD1T0 Eosine I Bluish Eosin B 2-(4,5-Dibromo-3,6-dihydroxy-2,7-dinitroxanthen-9-yl)-benzoic acid, disodium salt Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, sodium salt (1:2) Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, disodium salt AI3-63053 EINECS 208-943-1 C.I. 45400 C.I. Acid Red 91 Dibromodinitrofluorescein sodium Eosin BA Eosine B Eosine BA Eosine BN Eosine BNX Saffrosine UNII-OMS4XQD1T0" [P]. 中国发明专利, 专利号 CN 110214329 B, 授权公告日 2023-06-25.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of 伊红 B in Pharmaceutical Formulations". Food Chem., 2014, 2472, 4944-4953.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 伊红 B as an Impurity". J. Pharm. Biomed. Anal., 2014, 826, 417-434.
  3. Brown R C, Davis S M. "Identification and Structural Characterization of a Novel Degradation Product of 548-24-3 OMS4XQD1T0 Eosine I Bluish Eosin B 2-(4,5-Dibromo-3,6-dihydroxy-2,7-dinitroxanthen-9-yl)-benzoic acid, disodium salt Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, sodium salt (1:2) Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4',5'-dibromo-3',6'-dihydroxy-2',7'-dinitro-, disodium salt AI3-63053 EINECS 208-943-1 C.I. 45400 C.I. Acid Red 91 Dibromodinitrofluorescein sodium Eosin BA Eosine B Eosine BA Eosine BN Eosine BNX Saffrosine UNII-OMS4XQD1T0 Using HRMS and NMR". Biomed. Chromatogr., 2023, 686, (12), 8285-8294.
  4. Fischer P, Wagner E. "Forced Degradation Studies to Evaluate 伊红 B Profile in Drug Substances According to ICH Guidelines". Sci. Total Environ., 2021, 1482, (9), 3738-3748.

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...