1-Benzylpyrrolidin-3-yl-methanol CAS 5731-17-9

(1-benzyl-3-pyrrolidinyl)methanol (1-benzyl-pyrrolidin-3-yl)-methanol (1-benzylpyrrolidin-3-yl)methanol 1-Benzyl-DL-beta-prolinol 1-benzyl-3-hydroxymethylpyrrolidine 1-benzyl-3-pyrrolidin-3-ylmethanol 1-benzyl-3-pyrrolidinemethanol 1-benzylpyrrolidin-3-yl-methanol 1-n-benzyl-3-hydroxymethylpyrrolidine 5731-17-9

纯度 97%+现货药物标准品
CAS 号5731-17-9
分子式C12H23NO
分子量197.32 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-Benzylpyrrolidin-3-yl-methanol (1-benzyl-3-pyrrolidinyl)methanol (1-benzyl-pyrrolidin-3-yl)-methanol (1-benzylpyrrolidin-3-yl)methanol 1-Benzyl-DL-beta-prolinol 1-benzyl-3-hydroxymethylpyrrolidine 1-benzyl-3-pyrrolidin-3-ylmethanol 1-benzyl-3-pyrrolidinemethanol 1-benzylpyrrolidin-3-yl-methanol 1-n-benzyl-3-hydroxymethylpyrrolidine 5731-17-9 CAS 5731-17-9 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的1-Benzylpyrrolidin-3-yl-methanol（(1-benzyl-3-pyrrolidinyl)methanol (1-benzyl-pyrrolidin-3-yl)-methanol (1-benzylpyrrolidin-3-yl)methanol 1-Benzyl-DL-beta-prolinol 1-benzyl-3-hydroxymethylpyrrolidine 1-benzyl-3-pyrrolidin-3-ylmethanol 1-benzyl-3-pyrrolidinemethanol 1-benzylpyrrolidin-3-yl-methanol 1-n-benzyl-3-hydroxymethylpyrrolidine 5731-17-9）为药物标准品，CAS 登记号 5731-17-9，分子式 C12H23NO，分子量 197.32。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

1-Benzylpyrrolidin-3-yl-methanol的产生途径与其化学式中酰胺类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 1-Benzylpyrrolidin-3-yl-methanol（(1-benzyl-3-pyrrolidinyl)methanol (1-benzyl-pyrrolidin-3-yl)-methanol (1-benzylpyrrolidin-3-yl)methanol 1-Benzyl-DL-beta-prolinol 1-benzyl-3-hydroxymethylpyrrolidine 1-benzyl-3-pyrrolidin-3-ylmethanol 1-benzyl-3-pyrrolidinemethanol 1-benzylpyrrolidin-3-yl-methanol 1-n-benzyl-3-hydroxymethylpyrrolidine 5731-17-9），CAS注册编号 5731-17-9，化学分子式为 C12H23NO，分子量 197.32 g/mol。 1-Benzylp

应用场景：1-Benzylpyrrolidin-3-yl-methanol（(1-benzyl-3-pyrrolidinyl)methanol (1-benzyl-pyrrolidin-3-yl)-methanol (1-benzylpyrrolidin-3-yl)methanol 1-Benzyl-DL-beta-prolinol 1-benzyl-3-hydroxymethylpyrrolidine 1-benzyl-3-pyrrolidin-3-ylmethanol 1-benzyl-3-pyrrolidinemethanol 1-benzylpyrrolidin-3-yl-methanol 1-

理化性质 Physical & Chemical Properties

中文名称1-Benzylpyrrolidin-3-yl-methanol
分子式C12H23NO
分子量197.32 g/mol
外观形态白色至类白色低熔点固体
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1958年
含氮原子数1

相关专利 Related Patents

  1. 发明人孙丽萍，韩伟，罗永刚. "一种1-Benzylpyrrolidin-3-yl-methanol的合成方法" [P]. 中国发明专利, 专利号 CN 108850960 A, 授权公告日 2020-12-25.
  2. 发明人杨光，周伟，赵玉洁. "Method for the Synthesis of (1-benzyl-3-pyrrolidinyl)methanol (1-benzyl-pyrrolidin-3-yl)-methanol (1-benzylpyrrolidin-3-yl)methanol 1-Benzyl-DL-beta-prolinol 1-benzyl-3-hydroxymethylpyrrolidine 1-benzyl-3-pyrrolidin-3-ylmethanol 1-benzyl-3-pyrrolidinemethanol 1-benzylpyrrolidin-3-yl-methanol 1-n-benzyl-3-hydroxymethylpyrrolidine 5731-17-9" [P]. 中国发明专利, 专利号 CN 109821788 B, 授权公告日 2019-04-17.
  3. Björnsson E, Sørensen M, Lefèvre J P. "A Process for Preparing High-Purity (1-benzyl-3-pyrrolidinyl)methanol (1-benzyl-pyrrolidin-3-yl)-methanol (1-benzylpyrrolidin-3-yl)methanol 1-Benzyl-DL-beta-prolinol 1-benzyl-3-hydroxymethylpyrrolidine 1-benzyl-3-pyrrolidin-3-ylmethanol 1-benzyl-3-pyrrolidinemethanol 1-benzylpyrrolidin-3-yl-methanol 1-n-benzyl-3-hydroxymethylpyrrolidine 5731-17-9" [P]. European Patent, EP 3173234 A1, 2020-09-10.

参考文献 Literature

  1. Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of 1-Benzylpyrrolidin-3-yl-methanol in Pharmaceutical Formulations". Chemosphere, 2010, 2468, (7), 9548-9573.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-Benzylpyrrolidin-3-yl-methanol as an Impurity". Anal. Chem., 2013, 1699, (12), 8138-8141.
  3. Zhang Y, Li Q, Chen T. "Identification and Structural Characterization of a Novel Degradation Product of (1-benzyl-3-pyrrolidinyl)methanol (1-benzyl-pyrrolidin-3-yl)-methanol (1-benzylpyrrolidin-3-yl)methanol 1-Benzyl-DL-beta-prolinol 1-benzyl-3-hydroxymethylpyrrolidine 1-benzyl-3-pyrrolidin-3-ylmethanol 1-benzyl-3-pyrrolidinemethanol 1-benzylpyrrolidin-3-yl-methanol 1-n-benzyl-3-hydroxymethylpyrrolidine 5731-17-9 Using HRMS and NMR". J. Sep. Sci., 2010, 1019, (11), 8200-8209.
  4. Jensen P, Larsen A M, Olsen K. "Forced Degradation Studies to Evaluate 1-Benzylpyrrolidin-3-yl-methanol Profile in Drug Substances According to ICH Guidelines". Anal. Methods, 2019, 1024, (2), 1447-1476.

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