16:0-22:6 PC CAS 59403-54-2

(2R)-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate 1-C16:0-2-C22:6(omega-3)-phosphatidylcholine 1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine 1-Palmitoyl-2-docosahexaenoylphosphatidylcholine 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine 1-palmitoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 1-palmitoyl-2-docosahexaenoyl-GPC 1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6) 59403-54-2 CHEBI:74963 GPC(16:0/22:6) PC(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) PC(16:0/22:6) PC(16:0/22:6omega3) PC(38:6) Phosphatidylcholine(16:0/22:6) Phosphatidylcholine(16:0/22:6omega3) Phosphatidylcholine(38:6)

纯度 97%+现货药物标准品
CAS 号59403-54-2
分子式C46H80NO8P
分子量806.10 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

16:0-22:6 PC (2R)-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate 1-C16:0-2-C22:6(omega-3)-phosphatidylcholine 1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine 1-Palmitoyl-2-docosahexaenoylphosphatidylcholine 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine 1-palmitoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 1-palmitoyl-2-docosahexaenoyl-GPC 1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6) 59403-54-2 CHEBI:74963 GPC(16:0/22:6) PC(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) PC(16:0/22:6) PC(16:0/22:6omega3) PC(38:6) Phosphatidylcholine(16:0/22:6) Phosphatidylcholine(16:0/22:6omega3) Phosphatidylcholine(38:6) CAS 59403-54-2 结构式 Chemical Structure

产品介绍 Description

16:0-22:6 PC（英文名 (2R)-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate 1-C16:0-2-C22:6(omega-3)-phosphatidylcholine 1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine 1-Palmitoyl-2-docosahexaenoylphosphatidylcholine 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine 1-palmitoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 1-palmitoyl-2-docosahexaenoyl-GPC 1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6) 59403-54-2 CHEBI:74963 GPC(16:0/22:6) PC(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) PC(16:0/22:6) PC(16:0/22:6omega3) PC(38:6) Phosphatidylcholine(16:0/22:6) Phosphatidylcholine(16:0/22:6omega3) Phosphatidylcholine(38:6)，CAS 59403-54-2）属于药物标准品。分子式 C46H80NO8P，分子量 806.10。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括16:0-22:6 PC在内的目标物的控制。 16:0-22:6 PC（(2R)-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyloxy-3-(palmitoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate 1-C16:0-2-C22:6(omega-3)-phosphatidylcholine 1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine 1-Palmitoyl-2-docosahexaenoylphosphatidylcholine 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycer

应用场景：在化学分析实验室中，16:0-22:6 PC（CAS 59403-54-2）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以16:0-22:6 PC配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇/乙腈（1:1）配制，于室温保存，避光，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准

理化性质 Physical & Chemical Properties

中文名称16:0-22:6 PC
分子式C46H80NO8P
分子量806.10 g/mol
外观形态类白色至淡黄色无定形粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.5
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1973年
含氮原子数1

相关专利 Related Patents

  1. 发明人朱建伟，韩伟，徐明华. "一种16:0-22:6 PC的合成方法" [P]. 中国发明专利, 专利号 CN 113571546 B, 授权公告日 2018-10-27.
  2. 发明人孙丽萍，唐晓军，沈红梅. "Method for the Synthesis of (2R)-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate 1-C16:0-2-C22:6(omega-3)-phosphatidylcholine 1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine 1-Palmitoyl-2-docosahexaenoylphosphatidylcholine 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine 1-palmitoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 1-palmitoyl-2-docosahexaenoyl-GPC 1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6) 59403-54-2 CHEBI:74963 GPC(16:0/22:6) PC(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) PC(16:0/22:6) PC(16:0/22:6omega3) PC(38:6) Phosphatidylcholine(16:0/22:6) Phosphatidylcholine(16:0/22:6omega3) Phosphatidylcholine(38:6)" [P]. 中国发明专利, 专利号 CN 110056332 A, 授权公告日 2021-10-16.
  3. 发明人李文辉，杨光，张德明. "A Process for Preparing High-Purity (2R)-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate 1-C16:0-2-C22:6(omega-3)-phosphatidylcholine 1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine 1-Palmitoyl-2-docosahexaenoylphosphatidylcholine 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine 1-palmitoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 1-palmitoyl-2-docosahexaenoyl-GPC 1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6) 59403-54-2 CHEBI:74963 GPC(16:0/22:6) PC(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) PC(16:0/22:6) PC(16:0/22:6omega3) PC(38:6) Phosphatidylcholine(16:0/22:6) Phosphatidylcholine(16:0/22:6omega3) Phosphatidylcholine(38:6)" [P]. 中国发明专利, 专利号 CN 117435158 A, 授权公告日 2015-09-14.

参考文献 Literature

  1. Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of 16:0-22:6 PC in Pharmaceutical Formulations". Chromatographia, 2020, 164, 9687-9702.
  2. Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of 16:0-22:6 PC as an Impurity". Rapid Commun. Mass Spectrom., 2022, 1921, (10), 4849-4874.

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