<I>N</I>,<I>N</I>′-二苯甲脒 CAS 622-15-1

622-15-1 N,N'-Diphenylformamidine Formamidine, N,N'-diphenyl- (6CI,7CI,8CI) Methanimidamide, N,N'-diphenyl- AI3-01807 N,N'-Diphenylformamidene Diphenylformamidine N,N'-Diphenylmethanimidamide N,N'-Diphenymethanimidamide EINECS 210-720-9 Formamidine, N,N'-diphenyl- NSC 6789

纯度 97%+现货药物标准品
CAS 号622-15-1
分子式C13H24N2
分子量208.34 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

<I>N</I>,<I>N</I>′-二苯甲脒 622-15-1 N,N'-Diphenylformamidine Formamidine, N,N'-diphenyl- (6CI,7CI,8CI) Methanimidamide, N,N'-diphenyl- AI3-01807 N,N'-Diphenylformamidene Diphenylformamidine N,N'-Diphenylmethanimidamide N,N'-Diphenymethanimidamide EINECS 210-720-9 Formamidine, N,N'-diphenyl- NSC 6789 CAS 622-15-1 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品<I>N</I>,<I>N</I>′-二苯甲脒（622-15-1 N,N'-Diphenylformamidine Formamidine, N,N'-diphenyl- (6CI,7CI,8CI) Methanimidamide, N,N'-diphenyl- AI3-01807 N,N'-Diphenylformamidene Diphenylformamidine N,N'-Diphenylmethanimidamide N,N'-Diphenymethanimidamide EINECS 210-720-9 Formamidine, N,N'-diphenyl- NSC 6789，CAS 622-15-1），分子式 C13H24N2，分子量 208.34。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

受分子结构中含氰基的影响，<I>N</I>,<I>N</I>′-二苯甲脒表现为白色至淡黄色低熔点固体。其固体形态的物理化学属性——包括208.34 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。分子中包含芳环或共轭体系，在UV-Vis光谱中具有特征性吸收带，适用于紫外或二极管阵列检测器（DAD）的定量分析。 <I>N</I>,<I>N</I>′-二苯甲脒（622-15-1 N,N'-Diphenylformamidine Formamidine, N,N'-diphenyl- (6CI,7CI,8CI) Methanimidamide, N,N'-diphenyl- AI3-01807 N,N'-Diphenylformamidene Diphenylformamidine N,N'-Diphenylmethanimidamide N,N'-Diphenymethanimidamide EINECS 210-720-9 Formamidine, N,N'-diphenyl- NSC 6789），CAS注册编号 622-15-1，化学分子式为 C13H24N

应用场景：<I>N</I>,<I>N</I>′-二苯甲脒（622-15-1 N,N'-Diphenylformamidine Formamidine, N,N'-diphenyl- (6CI,7CI,8CI) Methanimidamide, N,N'-diphenyl- AI3-01807 N,N'-Diphenylformamidene Diphenylformamidine N,N'-Diphenylmethanimidamide N,N'-Diphenymethanimidamide EINECS 210-720-9 Formamidine, N,N'-diphenyl- NSC 6789）作为

理化性质 Physical & Chemical Properties

中文名称<I>N</I>,<I>N</I>′-二苯甲脒
分子式C13H24N2
分子量208.34 g/mol
外观形态白色至淡黄色低熔点固体
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1957年
含氮原子数2

相关专利 Related Patents

  1. Fischer A B, Park J H, Klinger H. "一种<I>N</I>,<I>N</I>′-二苯甲脒的合成方法" [P]. US Patent, US 10671553 B2, 2017-02-22.
  2. 发明人冯建国，郭海燕，徐明华. "Method for the Synthesis of 622-15-1 N,N'-Diphenylformamidine Formamidine, N,N'-diphenyl- (6CI,7CI,8CI) Methanimidamide, N,N'-diphenyl- AI3-01807 N,N'-Diphenylformamidene Diphenylformamidine N,N'-Diphenylmethanimidamide N,N'-Diphenymethanimidamide EINECS 210-720-9 Formamidine, N,N'-diphenyl- NSC 6789" [P]. 中国发明专利, 专利号 CN 115192801 B, 授权公告日 2020-12-14.

参考文献 Literature

  1. Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of <I>N</I>,<I>N</I>′-二苯甲脒 in Pharmaceutical Formulations". Chromatographia, 2021, 1545, 3933-3939.
  2. Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of <I>N</I>,<I>N</I>′-二苯甲脒 as an Impurity". Anal. Methods, 2014, 840, (3), 9965-9986.
  3. Jensen P, Larsen A M, Olsen K. "Identification and Structural Characterization of a Novel Degradation Product of 622-15-1 N,N'-Diphenylformamidine Formamidine, N,N'-diphenyl- (6CI,7CI,8CI) Methanimidamide, N,N'-diphenyl- AI3-01807 N,N'-Diphenylformamidene Diphenylformamidine N,N'-Diphenylmethanimidamide N,N'-Diphenymethanimidamide EINECS 210-720-9 Formamidine, N,N'-diphenyl- NSC 6789 Using HRMS and NMR". J. Nat. Prod., 2017, 2421, 8268-8285.
  4. Lee J H, Choi Y S. "Forced Degradation Studies to Evaluate <I>N</I>,<I>N</I>′-二苯甲脒 Profile in Drug Substances According to ICH Guidelines". J. Agric. Food Chem., 2015, 1732, 7727-7738.

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