13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride CAS 63251-92-3

13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride

纯度 97%+现货药物标准品
CAS 号63251-92-3
分子式C21H24NO5 Cl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride 13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride CAS 63251-92-3 结构式 Chemical Structure

产品介绍 Description

13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride（英文名 13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride，CAS 63251-92-3）属于药物标准品。分子式 C21H24NO5 Cl。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-1,3dioxolo4,5-gisoquinolino3,2-aisoquinolin-7-ium chloride（分子式 C21H24NO5 Cl）的化学结构中包含黄酮骨架，酰胺类，含羟基，含醚键，含氯取代。在反相色谱体系中，其保留行为主要受含氮官能团的质子化状态影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。由于结构中存在共轭发色团，该化合物在200-400 nm区间具有显著的紫外吸收，便于HPLC-UV检测。 化学式为 C21H24NO5 Cl 的13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-1,3dioxolo4,5-gisoquinolino3,2-aisoquinolin-7-ium chloride（13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-1,3

应用场景：13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro- 1,3 dioxolo 4,5-g isoquinolino 3,2-a isoquinolin-7-ium chloride（13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro- 1,3 dioxolo 4,5-g isoquinolino 3,2-a isoquinolin-7-ium chloride，CAS 63251-92-3）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以13a-

理化性质 Physical & Chemical Properties

中文名称13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride
分子式C21H24NO5 Cl
分子量405.88 g/mol
外观形态淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1975年
卤素含量Cl取代
含氮原子数1

相关专利 Related Patents

  1. 发明人张德明，钱学锋，韩伟. "一种13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride的合成方法" [P]. 中国发明专利, 专利号 CN 113052494 B, 授权公告日 2015-01-10.
  2. 发明人周伟，罗永刚，李文辉. "Method for the Synthesis of 13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride" [P]. 中国发明专利, 专利号 CN 115361971 A, 授权公告日 2017-02-07.

参考文献 Literature

  1. Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of 13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride in Pharmaceutical Formulations". Environ. Sci. Technol., 2011, 1469, 4461-4482.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride as an Impurity". Phytochemistry, 2014, 1071, (8), 584-608.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of 13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride Using HRMS and NMR". J. Chromatogr. A, 2021, 1450, 9634-9647.
  4. Zhou X P, Huang L, Wu G. "Forced Degradation Studies to Evaluate 13a-hydroxy-9,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride Profile in Drug Substances According to ICH Guidelines". Molecules, 2017, 409, (8), 9553-9557.

Related a Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...