2-(二环己基膦)-1-(2-甲氧苯基)-1<I>H</I>-吡咯 CAS 672937-63-2

1-(2-Methoxyphenyl)-2-(dicyclohexylphosphino)pyrrole 672937-63-2 1-(2-METHOXYPHENYL)-2-(DICYCLOHEXYLPHOSPHINO)PYRROLE;2-(DICYCLOHEXYLPHOSPHINO)-1-(2-METHOXYPHENYL)-1H-PYRROLE;CATACXIUM(R) POMECY SC11187

纯度 97%+现货药物标准品
CAS 号672937-63-2
分子式C23H42NOP
分子量379.56 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-(二环己基膦)-1-(2-甲氧苯基)-1<I>H</I>-吡咯 1-(2-Methoxyphenyl)-2-(dicyclohexylphosphino)pyrrole 672937-63-2 1-(2-METHOXYPHENYL)-2-(DICYCLOHEXYLPHOSPHINO)PYRROLE;2-(DICYCLOHEXYLPHOSPHINO)-1-(2-METHOXYPHENYL)-1H-PYRROLE;CATACXIUM(R) POMECY SC11187 CAS 672937-63-2 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的2-(二环己基膦)-1-(2-甲氧苯基)-1<I>H</I>-吡咯（1-(2-Methoxyphenyl)-2-(dicyclohexylphosphino)pyrrole 672937-63-2 1-(2-METHOXYPHENYL)-2-(DICYCLOHEXYLPHOSPHINO)PYRROLE;2-(DICYCLOHEXYLPHOSPHINO)-1-(2-METHOXYPHENYL)-1H-PYRROLE;CATACXIUM(R) POMECY SC11187）为药物标准品，CAS 登记号 672937-63-2，分子式 C23H42NOP，分子量 379.56。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

化学式为 C23H42NOP 的2-(二环己基膦)-1-(2-甲氧苯基)-1<I>H</I>-吡咯（1-(2-Methoxyphenyl)-2-(dicyclohexylphosphino)pyrrole 672937-63-2 1-(2-METHOXYPHENYL)-2-(DICYCLOHEXYLPHOSPHINO)PYRROLE;2-(DICYCLOHEXYLPHOSPHINO)-1-(2-METHOXYPHENYL)-1H-PYRROLE;CATACXIUM(R) POMECY SC11187），其CAS登记号是 672937-63-2，分子量为 379.56 g/mol。 依据分子式为 C23H42NOP 的2-(二环己基膦)-1-(2-甲氧苯基)-1<I>H</I>-吡咯结构特征，其分子内含酰胺类，有机磷，含羟基，含醚键，这意味着该化合物在紫外光谱中会呈现特征性的吸收带。分子量 379.56 g/mol 这一参数对质谱检测中的分子离子峰识别具有直接参考价值。含氮官能团的存在使该化合物在ESI正离子模式下具有优良的离子化效率，适合LC-MS/MS分析。 本品适用于HPL

应用场景：针对化学分析用途，2-(二环己基膦)-1-(2-甲氧苯基)-1<I>H</I>-吡咯（1-(2-Methoxyphenyl)-2-(dicyclohexylphosphino)pyrrole 672937-63-2 1-(2-METHOXYPHENYL)-2-(DICYCLOHEXYLPHOSPHINO)PYRROLE;2-(DICYCLOHEXYLPHOSPHINO)-1-(2-METHOXYPHENYL)-1H-PYRROLE;CATACXIUM(R) POMECY SC11187）是具有明确定量溯源的认证级对照品。 推荐以2-(二环己基膦)-1-(2-甲氧苯基)-1<I>H</I>-吡

理化性质 Physical & Chemical Properties

中文名称2-(二环己基膦)-1-(2-甲氧苯基)-1<I>H</I>-吡咯
分子式C23H42NOP
分子量379.56 g/mol
外观形态白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.5
UV特征有紫外吸收
CAS登记年份（估）1985年
含氮原子数1

相关专利 Related Patents

  1. Schröder R, Stevens L M, Roberts E F. "一种2-(二环己基膦)-1-(2-甲氧苯基)-1<I>H</I>-吡咯的合成方法" [P]. US Patent, US 10168349 B2, 2022-04-14.
  2. 发明人李文辉，高志强，郑宇鹏. "Method for the Synthesis of 1-(2-Methoxyphenyl)-2-(dicyclohexylphosphino)pyrrole 672937-63-2 1-(2-METHOXYPHENYL)-2-(DICYCLOHEXYLPHOSPHINO)PYRROLE;2-(DICYCLOHEXYLPHOSPHINO)-1-(2-METHOXYPHENYL)-1H-PYRROLE;CATACXIUM(R) POMECY SC11187" [P]. 中国发明专利, 专利号 CN 111495399 A, 授权公告日 2025-02-06.
  3. 发明人张德明，李文辉，杨光. "A Process for Preparing High-Purity 1-(2-Methoxyphenyl)-2-(dicyclohexylphosphino)pyrrole 672937-63-2 1-(2-METHOXYPHENYL)-2-(DICYCLOHEXYLPHOSPHINO)PYRROLE;2-(DICYCLOHEXYLPHOSPHINO)-1-(2-METHOXYPHENYL)-1H-PYRROLE;CATACXIUM(R) POMECY SC11187" [P]. 中国发明专利, 专利号 CN 109908924 B, 授权公告日 2016-12-22.

参考文献 Literature

  1. Jensen P, Larsen A M, Olsen K. "Development and Validation of an LC-MS/MS Method for the Determination of 2-(二环己基膦)-1-(2-甲氧苯基)-1<I>H</I>-吡咯 in Pharmaceutical Formulations". J. Agric. Food Chem., 2015, 1079, 7459-7479.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-(二环己基膦)-1-(2-甲氧苯基)-1<I>H</I>-吡咯 as an Impurity". Food Chem., 2012, 1975, 1278-1292.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of 1-(2-Methoxyphenyl)-2-(dicyclohexylphosphino)pyrrole 672937-63-2 1-(2-METHOXYPHENYL)-2-(DICYCLOHEXYLPHOSPHINO)PYRROLE;2-(DICYCLOHEXYLPHOSPHINO)-1-(2-METHOXYPHENYL)-1H-PYRROLE;CATACXIUM(R) POMECY SC11187 Using HRMS and NMR". Biomed. Chromatogr., 2024, 1652, 6495-6504.
  4. Kowalski T, Nowak Z. "Forced Degradation Studies to Evaluate 2-(二环己基膦)-1-(2-甲氧苯基)-1<I>H</I>-吡咯 Profile in Drug Substances According to ICH Guidelines". Chemosphere, 2011, 1978, (10), 5328-5351.

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