Sorbinil CAS 68367-52-2

(4S)-6-fluoro-2,3-dihydro-2'H,5'H-spiro[chromene-4,4'-imidazolidine]-2',5'-dione (4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione 68367-52-2 CP 45634 CP-45634 D-6-fluoro-spiro(chroman-4,4'-imidazolidine)-2',5'-dione D02CGC SBI Sorbinil Sorbinil (USAN/INN) Sorbinilo Sorbinilo [Spanish] Sorbinilum Sorbinilum [Latin]

纯度 97%+现货药物标准品
CAS 号68367-52-2
分子式C11H15FN2O3
分子量242.25 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Sorbinil (4S)-6-fluoro-2,3-dihydro-2'H,5'H-spiro[chromene-4,4'-imidazolidine]-2',5'-dione (4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione 68367-52-2 CP 45634 CP-45634 D-6-fluoro-spiro(chroman-4,4'-imidazolidine)-2',5'-dione D02CGC SBI Sorbinil Sorbinil (USAN/INN) Sorbinilo Sorbinilo [Spanish] Sorbinilum Sorbinilum [Latin] CAS 68367-52-2 结构式 Chemical Structure

产品介绍 Description

Sorbinil（(4S)-6-fluoro-2,3-dihydro-2'H,5'H-spiro[chromene-4,4'-imidazolidine]-2',5'-dione (4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione 68367-52-2 CP 45634 CP-45634 D-6-fluoro-spiro(chroman-4,4'-imidazolidine)-2',5'-dione D02CGC SBI Sorbinil Sorbinil (USAN/INN) Sorbinilo Sorbinilo [Spanish] Sorbinilum Sorbinilum [Latin]）是药物分析与质量控制领域常用的药物标准品，CAS 号 68367-52-2。分子式 C11H15FN2O3，分子量 242.25。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯源要求。适用于GLP实验室的日常分析。 CAS编号 68367-52-2 对应的化合物Sorbinil（英文标识 (4S)-6-fluoro-2,3-dihydro-2'H,5'H-spirochromene-4,4'-imidazolidine-2',5'-dione (4S)-6-fluorospiro2,3-dihydrochromene-4,5'-imidazolidine-2',4'-dione 68367-52-2 CP 45634 CP-45634 D-6-fluoro-spiro(chroman-4,4'-imidazolidine)-2',5'-dione D02CGC SBI Sorbinil Sorbinil (USAN/INN) Sorbinilo Sorbinilo Spanish Sorbinilum Sorbinilum Latin），化学式 C11H15FN2O3，相对分子质量 242.25。 Sorbinil（分子式 C11H15F

应用场景：针对化学分析用途，Sorbinil（(4S)-6-fluoro-2,3-dihydro-2'H,5'H-spiro chromene-4,4'-imidazolidine -2',5'-dione (4S)-6-fluorospiro 2,3-dihydrochromene-4,5'-imidazolidine -2',4'-dione 68367-52-2 CP 45634 CP-45634 D-6-fluoro-spiro(chroman-4,4'-imidazolidine)-2',5'-dione D02CGC SBI Sorbinil Sorbinil (USAN/INN) Sorb

理化性质 Physical & Chemical Properties

中文名称Sorbinil
分子式C11H15FN2O3
分子量242.25 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮，密闭保存防止挥发
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1976年
卤素含量F取代
含氮原子数2

相关专利 Related Patents

  1. 发明人朱建伟，周伟，张德明. "一种Sorbinil的合成方法" [P]. 中国发明专利, 专利号 CN 114211632 A, 授权公告日 2024-03-13.
  2. 发明人朱建伟，唐晓军，胡光. "Method for the Synthesis of (4S)-6-fluoro-2,3-dihydro-2'H,5'H-spiro[chromene-4,4'-imidazolidine]-2',5'-dione (4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione 68367-52-2 CP 45634 CP-45634 D-6-fluoro-spiro(chroman-4,4'-imidazolidine)-2',5'-dione D02CGC SBI Sorbinil Sorbinil (USAN/INN) Sorbinilo Sorbinilo [Spanish] Sorbinilum Sorbinilum [Latin]" [P]. 中国发明专利, 专利号 CN 113108806 B, 授权公告日 2018-01-11.

参考文献 Literature

  1. Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of Sorbinil in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2025, 111, 901-913.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of Sorbinil as an Impurity". Molecules, 2012, 208, (5), 7784-7804.
  3. Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of (4S)-6-fluoro-2,3-dihydro-2'H,5'H-spiro[chromene-4,4'-imidazolidine]-2',5'-dione (4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione 68367-52-2 CP 45634 CP-45634 D-6-fluoro-spiro(chroman-4,4'-imidazolidine)-2',5'-dione D02CGC SBI Sorbinil Sorbinil (USAN/INN) Sorbinilo Sorbinilo [Spanish] Sorbinilum Sorbinilum [Latin] Using HRMS and NMR". J. Pharm. Biomed. Anal., 2020, 854, 6866-6882.
  4. Fischer P, Wagner E. "Forced Degradation Studies to Evaluate Sorbinil Profile in Drug Substances According to ICH Guidelines". Sci. Total Environ., 2022, 584, (5), 6995-7015.

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