聚乙二醇-<i>嵌段</i>-聚丙二醇-<i>嵌段</i>-聚乙二醇 CAS 691397-13-4
09Y8E6164A 1S66E28KXA 2E9U4Y94DB G6DQL26D50 IS93EQR73R JT3U72U71K JX0HIX6OAG LQA7B6G8JG PLU8QA2TOV TUF2IVW3M2 BIS92ZSF57 0R79529H48 40YKA808KW 66EV99AS9E 73V0D3O1FP 7YLA84208M 91B7KU0JTI 5Z46X21X7I B9Y8J911BV YWJ6837FL1 V8B3K56SW0 F75JV2T505 NZ1V84NDF9 KDW7VYE2Z8 64CHX343Y8 5K7JD3ELD7 JO9JD7WJ20 QDJ29LOA3J J2R38TWT27 E3JZI5G4RX UMG50ZW8UY CU4K26HG21 58SFJ9RW21 6SG11EPD3Z PH86TYV5Y9 3O0G38UT27 M1X5Y5T2QD XPP85ZHV76 691397-13-4 UNII-G6DQL26D50 UNII-TUF2IVW3M2 UNII-IS93EQR73R UNII-JT3U72U71K UNII-JX0HIX6OAG UNII-LQA7B6G8JG UNII-PLU8QA2TOV UNII-09Y8E6164A Oxirane, 2-methyl-, polymer with oxirane, triblock Ethylene glycol-propylene glycol copolymer triblock ExpertGel 56 Adeka Pluronic L 101 Acclaim 2220N Antarox L 61 Blaunon P 124 UNII-2E9U4Y94DB UNII-1S66E28KXA Pluronic P 85 Pluronic P-85 UNII-BIS92ZSF57 Poloxalene Vepoloxamer [USAN] Vepoloxamer Poloxamer 124 Poloxamer 181 Poloxamer 182 Poloxamer 183 Poloxamer 184 Poloxamer 185 Poloxamer 188 Poloxamer 217 Poloxamer 234 Poloxamer 237 Poloxamer 331 Poloxamer 333 Poloxamer 334 Poloxamer 335 Poloxamer 338 Poloxamer 401 Poloxamer 403 Poloxalene [USAN:INN] Pluronic F-68 UNII-B9Y8J911BV UNII-YWJ6837FL1 UNII-5Z46X21X7I UNII-V8B3K56SW0 UNII-0R79529H48 UNII-40YKA808KW UNII-66EV99AS9E UNII-73V0D3O1FP UNII-7YLA84208M UNII-91B7KU0JTI UNII-XPP85ZHV76 Pluronic block copolymer p85 UNII-QDJ29LOA3J UNII-J2R38TWT27 UNII-E3JZI5G4RX UNII-UMG50ZW8UY UNII-CU4K26HG21 UNII-58SFJ9RW21 UNII-6SG11EPD3Z UNII-PH86TYV5Y9 UNII-3O0G38UT27 UNII-M1X5Y5T2QD UNII-NZ1V84NDF9 UNII-KDW7VYE2Z8 UNII-64CHX343Y8 UNII-5K7JD3ELD7 UNII-JO9JD7WJ20 UNII-F75JV2T505
| CAS 号 | 691397-13-4 |
| 分子式 | C7H16O4 |
| 分子量 | 164.20 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
本产品为药物标准品聚乙二醇-<i>嵌段</i>-聚丙二醇-<i>嵌段</i>-聚乙二醇（09Y8E6164A 1S66E28KXA 2E9U4Y94DB G6DQL26D50 IS93EQR73R JT3U72U71K JX0HIX6OAG LQA7B6G8JG PLU8QA2TOV TUF2IVW3M2 BIS92ZSF57 0R79529H48 40YKA808KW 66EV99AS9E 73V0D3O1FP 7YLA84208M 91B7KU0JTI 5Z46X21X7I B9Y8J911BV YWJ6837FL1 V8B3K56SW0 F75JV2T505 NZ1V84NDF9 KDW7VYE2Z8 64CHX343Y8 5K7JD3ELD7 JO9JD7WJ20 QDJ29LOA3J J2R38TWT27 E3JZI5G4RX UMG50ZW8UY CU4K26HG21 58SFJ9RW21 6SG11EPD3Z PH86TYV5Y9 3O0G38UT27 M1X5Y5T2QD XPP85ZHV76 691397-13-4 UNII-G6DQL26D50 UNII-TUF2IVW3M2 UNII-IS93EQR73R UNII-JT3U72U71K UNII-JX0HIX6OAG UNII-LQA7B6G8JG UNII-PLU8QA2TOV UNII-09Y8E6164A Oxirane, 2-methyl-, polymer with oxirane, triblock Ethylene glycol-propylene glycol copolymer triblock ExpertGel 56 Adeka Pluronic L 101 Acclaim 2220N Antarox L 61 Blaunon P 124 UNII-2E9U4Y94DB UNII-1S66E28KXA Pluronic P 85 Pluronic P-85 UNII-BIS92ZSF57 Poloxalene Vepoloxamer [USAN] Vepoloxamer Poloxamer 124 Poloxamer 181 Poloxamer 182 Poloxamer 183 Poloxamer 184 Poloxamer 185 Poloxamer 188 Poloxamer 217 Poloxamer 234 Poloxamer 237 Poloxamer 331 Poloxamer 333 Poloxamer 334 Poloxamer 335 Poloxamer 338 Poloxamer 401 Poloxamer 403 Poloxalene [USAN:INN] Pluronic F-68 UNII-B9Y8J911BV UNII-YWJ6837FL1 UNII-5Z46X21X7I UNII-V8B3K56SW0 UNII-0R79529H48 UNII-40YKA808KW UNII-66EV99AS9E UNII-73V0D3O1FP UNII-7YLA84208M UNII-91B7KU0JTI UNII-XPP85ZHV76 Pluronic block copolymer p85 UNII-QDJ29LOA3J UNII-J2R38TWT27 UNII-E3JZI5G4RX UNII-UMG50ZW8UY UNII-CU4K26HG21 UNII-58SFJ9RW21 UNII-6SG11EPD3Z UNII-PH86TYV5Y9 UNII-3O0G38UT27 UNII-M1X5Y5T2QD UNII-NZ1V84NDF9 UNII-KDW7VYE2Z8 UNII-64CHX343Y8 UNII-5K7JD3ELD7 UNII-JO9JD7WJ20 UNII-F75JV2T505，CAS 691397-13-4），分子式 C7H16O4，分子量 164.20。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。
在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括聚乙二醇-<i>嵌段</i>-聚丙二醇-<i>嵌段</i>-聚乙二醇在内的目标物的控制。 化学式为 C7H16O4 的聚乙二醇-<i>嵌段</i>-聚丙二醇-<i>嵌段</i>-聚乙二醇（09Y8E6164A 1S66E28KXA 2E9U4Y94DB G6DQL26D50 IS93EQR73R JT3U72U71K JX0HIX6OAG LQA7B6G8JG PLU8QA2TOV TUF2IVW3M2 BIS92ZSF57 0R79529H48 40YKA808KW 66EV99AS9E 73V0D3O1FP 7YLA84208M 91B7KU0JTI 5Z46X21X7I B9Y8J911BV YWJ6837FL1 V8B3K56SW0 F75JV2T505 NZ1V84NDF9 KDW7VYE2Z8 64CHX343Y8 5K7JD3ELD7 JO9JD7WJ20 QDJ29LOA3J J2R38TWT27 E3JZI5G4RX UMG50ZW8UY CU4K26HG21 58SFJ9RW21 6SG11EPD3Z P
应用场景：针对化学分析用途，聚乙二醇-<i>嵌段</i>-聚丙二醇-<i>嵌段</i>-聚乙二醇（09Y8E6164A 1S66E28KXA 2E9U4Y94DB G6DQL26D50 IS93EQR73R JT3U72U71K JX0HIX6OAG LQA7B6G8JG PLU8QA2TOV TUF2IVW3M2 BIS92ZSF57 0R79529H48 40YKA808KW 66EV99AS9E 73V0D3O1FP 7YLA84208M 91B7KU0JTI 5Z46X21X7I B9Y8J911BV YWJ6837FL1 V8B3K56SW0 F75JV2T505 NZ1V84NDF9 KDW
理化性质 Physical & Chemical Properties
| 中文名称 | 聚乙二醇-<i>嵌段</i>-聚丙二醇-<i>嵌段</i>-聚乙二醇 |
| 分子式 | C7H16O4 |
| 分子量 | 164.20 g/mol |
| 外观形态 | 白色至类白色结晶性粉末 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙醇、DMSO、水 |
| 稳定性 | 具有吸湿性，开封后应立即密封 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 0.0 |
| CAS登记年份（估） | 1985年 |
相关专利 Related Patents
- Jørgensen K, Schröder R, Lefèvre J P. "一种聚乙二醇-嵌段-聚丙二醇-嵌段-聚乙二醇的合成方法" [P]. European Patent, EP 3114968 A1, 2017-10-16.
- Rossi M, Nielsen H, Nowak P. "Method for the Synthesis of 09Y8E6164A 1S66E28KXA 2E9U4Y94DB G6DQL26D50 IS93EQR73R JT3U72U71K JX0HIX6OAG LQA7B6G8JG PLU8QA2TOV TUF2IVW3M2 BIS92ZSF57 0R79529H48 40YKA808KW 66EV99AS9E 73V0D3O1FP 7YLA84208M 91B7KU0JTI 5Z46X21X7I B9Y8J911BV YWJ6837FL1 V8B3K56SW0 F75JV2T505 NZ1V84NDF9 KDW7VYE2Z8 64CHX343Y8 5K7JD3ELD7 JO9JD7WJ20 QDJ29LOA3J J2R38TWT27 E3JZI5G4RX UMG50ZW8UY CU4K26HG21 58SFJ9RW21 6SG11EPD3Z PH86TYV5Y9 3O0G38UT27 M1X5Y5T2QD XPP85ZHV76 691397-13-4 UNII-G6DQL26D50 UNII-TUF2IVW3M2 UNII-IS93EQR73R UNII-JT3U72U71K UNII-JX0HIX6OAG UNII-LQA7B6G8JG UNII-PLU8QA2TOV UNII-09Y8E6164A Oxirane, 2-methyl-, polymer with oxirane, triblock Ethylene glycol-propylene glycol copolymer triblock ExpertGel 56 Adeka Pluronic L 101 Acclaim 2220N Antarox L 61 Blaunon P 124 UNII-2E9U4Y94DB UNII-1S66E28KXA Pluronic P 85 Pluronic P-85 UNII-BIS92ZSF57 Poloxalene Vepoloxamer [USAN] Vepoloxamer Poloxamer 124 Poloxamer 181 Poloxamer 182 Poloxamer 183 Poloxamer 184 Poloxamer 185 Poloxamer 188 Poloxamer 217 Poloxamer 234 Poloxamer 237 Poloxamer 331 Poloxamer 333 Poloxamer 334 Poloxamer 335 Poloxamer 338 Poloxamer 401 Poloxamer 403 Poloxalene [USAN:INN] Pluronic F-68 UNII-B9Y8J911BV UNII-YWJ6837FL1 UNII-5Z46X21X7I UNII-V8B3K56SW0 UNII-0R79529H48 UNII-40YKA808KW UNII-66EV99AS9E UNII-73V0D3O1FP UNII-7YLA84208M UNII-91B7KU0JTI UNII-XPP85ZHV76 Pluronic block copolymer p85 UNII-QDJ29LOA3J UNII-J2R38TWT27 UNII-E3JZI5G4RX UNII-UMG50ZW8UY UNII-CU4K26HG21 UNII-58SFJ9RW21 UNII-6SG11EPD3Z UNII-PH86TYV5Y9 UNII-3O0G38UT27 UNII-M1X5Y5T2QD UNII-NZ1V84NDF9 UNII-KDW7VYE2Z8 UNII-64CHX343Y8 UNII-5K7JD3ELD7 UNII-JO9JD7WJ20 UNII-F75JV2T505" [P]. European Patent, EP 3285194 A1, 2021-08-02.
参考文献 Literature
- O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of 聚乙二醇-嵌段-聚丙二醇-嵌段-聚乙二醇 in Pharmaceutical Formulations". Talanta, 2023, 1040, (3), 3660-3679.
- Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 聚乙二醇-嵌段-聚丙二醇-嵌段-聚乙二醇 as an Impurity". J. Pharm. Biomed. Anal., 2018, 298, (5), 2420-2436.
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