6-氰基吡啶-3-甲酸 CAS 70165-31-0

1-(4-Pyridinylmethyl)piperidine-4-carboxylic acid 1-(4-pyridinylmethyl)-4-piperidinecarboxylic acid 1-(pyridin-4-ylmethyl)piperidine-4-carboxylic acid 1-pyridin-4-ylmethyl-piperidine-4-carboxylic acid 1-pyridin-4-ylmethylpiperidine-4-carboxylic acid 6-Cyanonicotinic acid 6-Cyanopyridine-3-carboxylic acid 70165-31-0

纯度 97%+现货药物标准品
CAS 号70165-31-0
分子式C7H10N2O2
分子量154.17 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

6-氰基吡啶-3-甲酸 1-(4-Pyridinylmethyl)piperidine-4-carboxylic acid 1-(4-pyridinylmethyl)-4-piperidinecarboxylic acid 1-(pyridin-4-ylmethyl)piperidine-4-carboxylic acid 1-pyridin-4-ylmethyl-piperidine-4-carboxylic acid 1-pyridin-4-ylmethylpiperidine-4-carboxylic acid 6-Cyanonicotinic acid 6-Cyanopyridine-3-carboxylic acid 70165-31-0 CAS 70165-31-0 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的6-氰基吡啶-3-甲酸（1-(4-Pyridinylmethyl)piperidine-4-carboxylic acid 1-(4-pyridinylmethyl)-4-piperidinecarboxylic acid 1-(pyridin-4-ylmethyl)piperidine-4-carboxylic acid 1-pyridin-4-ylmethyl-piperidine-4-carboxylic acid 1-pyridin-4-ylmethylpiperidine-4-carboxylic acid 6-Cyanonicotinic acid 6-Cyanopyridine-3-carboxylic acid 70165-31-0）为药物标准品，CAS 登记号 70165-31-0，分子式 C7H10N2O2，分子量 154.17。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括6-氰基吡啶-3-甲酸在内的目标物的控制。 CAS编号 70165-31-0 对应的化合物6-氰基吡啶-3-甲酸（英文标识 1-(4-Pyridinylmethyl)piperidine-4-carboxylic acid 1-(4-pyridinylmethyl)-4-piperidinecarboxylic acid 1-(pyridin-4-ylmethyl)piperidine-4-carboxylic acid 1-pyridin-4-ylmethyl-piperidine-4-carboxylic acid 1-pyridin-4-ylmethylpiperidine-4-carboxylic acid 6-Cyanonicotinic acid 6-Cyanopyridine-3-carboxylic acid 70165-31-0），化学式 C7H10N2O2，相对分子质量 154.17。 6-氰基吡啶-3-甲酸（C7H10N2O2）含有氨基酸衍生物，酰胺类，含羟基，含醚键。具有较强的吸湿性，羧基赋予其一定

应用场景：6-氰基吡啶-3-甲酸（1-(4-Pyridinylmethyl)piperidine-4-carboxylic acid 1-(4-pyridinylmethyl)-4-piperidinecarboxylic acid 1-(pyridin-4-ylmethyl)piperidine-4-carboxylic acid 1-pyridin-4-ylmethyl-piperidine-4-carboxylic acid 1-pyridin-4-ylmethylpiperidine-4-carboxylic acid 6-Cyanonicotinic acid 6-Cyanopyridine-

理化性质 Physical & Chemical Properties

中文名称6-氰基吡啶-3-甲酸
分子式C7H10N2O2
分子量154.17 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1977年
含氮原子数2

相关专利 Related Patents

  1. 发明人陈志强，朱建伟，黄志刚. "一种6-氰基吡啶-3-甲酸的合成方法" [P]. 中国发明专利, 专利号 CN 108669444 B, 授权公告日 2018-08-20.
  2. 发明人黄志刚，韩伟，罗永刚. "Method for the Synthesis of 1-(4-Pyridinylmethyl)piperidine-4-carboxylic acid 1-(4-pyridinylmethyl)-4-piperidinecarboxylic acid 1-(pyridin-4-ylmethyl)piperidine-4-carboxylic acid 1-pyridin-4-ylmethyl-piperidine-4-carboxylic acid 1-pyridin-4-ylmethylpiperidine-4-carboxylic acid 6-Cyanonicotinic acid 6-Cyanopyridine-3-carboxylic acid 70165-31-0" [P]. 中国发明专利, 专利号 CN 108068052 B, 授权公告日 2018-12-24.

参考文献 Literature

  1. Garcia M, Rodriguez P. "Development and Validation of an LC-MS/MS Method for the Determination of 6-氰基吡啶-3-甲酸 in Pharmaceutical Formulations". Molecules, 2016, 166, 1831-1838.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 6-氰基吡啶-3-甲酸 as an Impurity". Chemosphere, 2025, 759, 6243-6257.
  3. Wang L, Li J, Zhang H. "Identification and Structural Characterization of a Novel Degradation Product of 1-(4-Pyridinylmethyl)piperidine-4-carboxylic acid 1-(4-pyridinylmethyl)-4-piperidinecarboxylic acid 1-(pyridin-4-ylmethyl)piperidine-4-carboxylic acid 1-pyridin-4-ylmethyl-piperidine-4-carboxylic acid 1-pyridin-4-ylmethylpiperidine-4-carboxylic acid 6-Cyanonicotinic acid 6-Cyanopyridine-3-carboxylic acid 70165-31-0 Using HRMS and NMR". Anal. Chim. Acta, 2022, 882, 4856-4863.
  4. Jensen P, Larsen A M, Olsen K. "Forced Degradation Studies to Evaluate 6-氰基吡啶-3-甲酸 Profile in Drug Substances According to ICH Guidelines". J. Pharm. Biomed. Anal., 2021, 2213, (8), 4266-4291.

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