1,1,1,3,3,3-六氟-2-苯基-2-丙醇 CAS 718-64-9

(Hexafluoro-2-hydroxyisopropyl)benzene A,A-Bis(trifluoromethyl)benzyl alcohol 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol hexafluoro-2-phenylisopropanol 1,1,1,3,3,3-hexafluoro-2-phenylpropan-2-ol 2-hydroxy-2-phenylhexafluoropropane 2,2,2,2',2',2'-hexafluorocumyl alcohol 2,2,2,2,2,2,-hexafluorocumyl alcohol 718-64-9

纯度 97%+现货药物标准品
CAS 号718-64-9
分子式C9H12F6O
分子量250.18 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1,1,1,3,3,3-六氟-2-苯基-2-丙醇 (Hexafluoro-2-hydroxyisopropyl)benzene A,A-Bis(trifluoromethyl)benzyl alcohol 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol hexafluoro-2-phenylisopropanol 1,1,1,3,3,3-hexafluoro-2-phenylpropan-2-ol 2-hydroxy-2-phenylhexafluoropropane 2,2,2,2',2',2'-hexafluorocumyl alcohol 2,2,2,2,2,2,-hexafluorocumyl alcohol 718-64-9 CAS 718-64-9 结构式 Chemical Structure

产品介绍 Description

1,1,1,3,3,3-六氟-2-苯基-2-丙醇（(Hexafluoro-2-hydroxyisopropyl)benzene A,A-Bis(trifluoromethyl)benzyl alcohol 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol hexafluoro-2-phenylisopropanol 1,1,1,3,3,3-hexafluoro-2-phenylpropan-2-ol 2-hydroxy-2-phenylhexafluoropropane 2,2,2,2',2',2'-hexafluorocumyl alcohol 2,2,2,2,2,2,-hexafluorocumyl alcohol 718-64-9，CAS 号 718-64-9）是 CATO 佳途自主生产的药物标准品，分子式 C9H12F6O，分子量 250.18。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括1,1,1,3,3,3-六氟-2-苯基-2-丙醇在内的目标物的控制。 1,1,1,3,3,3-六氟-2-苯基-2-丙醇（(Hexafluoro-2-hydroxyisopropyl)benzene A,A-Bis(trifluoromethyl)benzyl alcohol 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol hexafluoro-2-phenylisopropanol 1,1,1,3,3,3-hexafluoro-2-phenylpropan-2-ol 2-hydroxy-2-phenylhexafluoropropane 2,2,2,2',2',2'-hexafluorocumyl alcohol 2,2,2,2,2,2,-hexafluorocumyl alcohol 718-64-9），CAS注册编号 718-64-9，化学分子式为 C9H12F6O，分子量 250.18 g/mol。 从化学结构特征来看，1,1,1,3,3,3-六氟-2-苯基-2-丙醇的分子骨架中

应用场景：针对化学分析用途，1,1,1,3,3,3-六氟-2-苯基-2-丙醇（(Hexafluoro-2-hydroxyisopropyl)benzene A,A-Bis(trifluoromethyl)benzyl alcohol 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol hexafluoro-2-phenylisopropanol 1,1,1,3,3,3-hexafluoro-2-phenylpropan-2-ol 2-hydroxy-2-phenylhexafluoropropane 2,2,2,2',2',2'-hexafluorocumyl alco

理化性质 Physical & Chemical Properties

中文名称1,1,1,3,3,3-六氟-2-苯基-2-丙醇
分子式C9H12F6O
分子量250.18 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1957年
卤素含量F取代

相关专利 Related Patents

  1. 发明人张德明，罗永刚，周伟. "一种1,1,1,3,3,3-六氟-2-苯基-2-丙醇的合成方法" [P]. 中国发明专利, 专利号 CN 113196196 A, 授权公告日 2021-08-11.
  2. 发明人马晓峰，韩伟，冯建国. "Method for the Synthesis of (Hexafluoro-2-hydroxyisopropyl)benzene A,A-Bis(trifluoromethyl)benzyl alcohol 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol hexafluoro-2-phenylisopropanol 1,1,1,3,3,3-hexafluoro-2-phenylpropan-2-ol 2-hydroxy-2-phenylhexafluoropropane 2,2,2,2',2',2'-hexafluorocumyl alcohol 2,2,2,2,2,2,-hexafluorocumyl alcohol 718-64-9" [P]. 中国发明专利, 专利号 CN 117485640 B, 授权公告日 2015-04-13.
  3. Johansson L, Sørensen M, Kowalski A. "A Process for Preparing High-Purity (Hexafluoro-2-hydroxyisopropyl)benzene A,A-Bis(trifluoromethyl)benzyl alcohol 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol hexafluoro-2-phenylisopropanol 1,1,1,3,3,3-hexafluoro-2-phenylpropan-2-ol 2-hydroxy-2-phenylhexafluoropropane 2,2,2,2',2',2'-hexafluorocumyl alcohol 2,2,2,2,2,2,-hexafluorocumyl alcohol 718-64-9" [P]. European Patent, EP 3711061 A1, 2025-06-09.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of 1,1,1,3,3,3-六氟-2-苯基-2-丙醇 in Pharmaceutical Formulations". J. Chromatogr. A, 2014, 501, 5971-5976.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1,1,1,3,3,3-六氟-2-苯基-2-丙醇 as an Impurity". Chromatographia, 2013, 2215, (8), 2895-2899.
  3. Hughes D, Roberts J, Thomas A. "Identification and Structural Characterization of a Novel Degradation Product of (Hexafluoro-2-hydroxyisopropyl)benzene A,A-Bis(trifluoromethyl)benzyl alcohol 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol hexafluoro-2-phenylisopropanol 1,1,1,3,3,3-hexafluoro-2-phenylpropan-2-ol 2-hydroxy-2-phenylhexafluoropropane 2,2,2,2',2',2'-hexafluorocumyl alcohol 2,2,2,2,2,2,-hexafluorocumyl alcohol 718-64-9 Using HRMS and NMR". J. Nat. Prod., 2025, 1846, (5), 2398-2419.

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