CAS 7248-21-7

903A9K181P 7248-21-7 Iprazochrome [INN] Iprazochrome Hydrazinecarboxamide, 2-(3-hydroxy-1-(1-methylethyl)-6-oxo-1,2,3,6-tetrahydro-5H-indol-5-ylidene)- Hydrazinecarboxamide, 2-(1,2,3,6-tetrahydro-3-hydroxy-1-(1-methylethyl)-6-oxo-5H-indol-5-ylidene)- (9CI) 3-Hydroxy-1-isopropyl-5,6-indolinedione 5-semicarbazone 5,6-Indolinedione, 3-hydroxy-1-isopropyl-, 5-semicarbazone (8CI) 2-(1,2,3,6-Tetrahydro-3-hydroxy-1-(1-methylethyl)-6-oxo-5H-indol-5-ylidene)hydrazinecarboxamide Divascan 5,6-Indolinedione, 3-hydroxy-1-isopropyl-, 5-semicarbazone Iprazochromum [INN-Latin] Iprazocromo [INN-Spanish] ISI 1-Isopropyl-3-hydroxy-5-semicarbazone-6-oxo-2,3,5,6-tetrahydroindole Isopropylnoradenochrome monosemicarbazone Isopropylnoradrenochrome monosemicarbazone Novochrome NSC 10065 Iprazochromum Iprazocromo UNII-903A9K181P

纯度 97%+现货药物标准品
CAS 号7248-21-7
分子式C12H16N4O3
分子量264.28 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

903A9K181P 7248-21-7 Iprazochrome [INN] Iprazochrome Hydrazinecarboxamide, 2-(3-hydroxy-1-(1-methylethyl)-6-oxo-1,2,3,6-tetrahydro-5H-indol-5-ylidene)- Hydrazinecarboxamide, 2-(1,2,3,6-tetrahydro-3-hydroxy-1-(1-methylethyl)-6-oxo-5H-indol-5-ylidene)- (9CI) 3-Hydroxy-1-isopropyl-5,6-indolinedione 5-semicarbazone 5,6-Indolinedione, 3-hydroxy-1-isopropyl-, 5-semicarbazone (8CI) 2-(1,2,3,6-Tetrahydro-3-hydroxy-1-(1-methylethyl)-6-oxo-5H-indol-5-ylidene)hydrazinecarboxamide Divascan 5,6-Indolinedione, 3-hydroxy-1-isopropyl-, 5-semicarbazone Iprazochromum [INN-Latin] Iprazocromo [INN-Spanish] ISI 1-Isopropyl-3-hydroxy-5-semicarbazone-6-oxo-2,3,5,6-tetrahydroindole Isopropylnoradenochrome monosemicarbazone Isopropylnoradrenochrome monosemicarbazone Novochrome NSC 10065 Iprazochromum Iprazocromo UNII-903A9K181P CAS 7248-21-7 结构式 Chemical Structure

产品介绍 Description

（903A9K181P 7248-21-7 Iprazochrome [INN] Iprazochrome Hydrazinecarboxamide, 2-(3-hydroxy-1-(1-methylethyl)-6-oxo-1,2,3,6-tetrahydro-5H-indol-5-ylidene)- Hydrazinecarboxamide, 2-(1,2,3,6-tetrahydro-3-hydroxy-1-(1-methylethyl)-6-oxo-5H-indol-5-ylidene)- (9CI) 3-Hydroxy-1-isopropyl-5,6-indolinedione 5-semicarbazone 5,6-Indolinedione, 3-hydroxy-1-isopropyl-, 5-semicarbazone (8CI) 2-(1,2,3,6-Tetrahydro-3-hydroxy-1-(1-methylethyl)-6-oxo-5H-indol-5-ylidene)hydrazinecarboxamide Divascan 5,6-Indolinedione, 3-hydroxy-1-isopropyl-, 5-semicarbazone Iprazochromum [INN-Latin] Iprazocromo [INN-Spanish] ISI 1-Isopropyl-3-hydroxy-5-semicarbazone-6-oxo-2,3,5,6-tetrahydroindole Isopropylnoradenochrome monosemicarbazone Isopropylnoradrenochrome monosemicarbazone Novochrome NSC 10065 Iprazochromum Iprazocromo UNII-903A9K181P）是药物分析与质量控制领域常用的药物标准品，CAS 号 7248-21-7。分子式 C12H16N4O3，分子量 264.28。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

与同类药物标准品相比，的分子量为264.28 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 7248-21-7 对应的化合物（英文标识 903A9K181P 7248-21-7 Iprazochrome INN Iprazochrome Hydrazinecarboxamide, 2-(3-hydroxy-1-(1-methylethyl)-6-oxo-1,2,3,6-tetrahydro-5H-indol-5-ylidene)- Hydrazinecarboxamide, 2-(1,2,3,6-tetrahydro-3-hydroxy-1-(1-methylethyl)-6-oxo-5H-indol-5-ylidene)- (9CI) 3-Hydroxy-1-isopropyl-5,6-indolinedione 5-semicarbazone 5,6-Indolinedione, 3-hydroxy-1-isopropyl-, 5-semicarbazone (8CI) 2-(1,2,3,6-Tetrahydro-3-hydroxy-1-(

应用场景：在化学分析实验室中，（CAS 7248-21-7）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇/乙腈（1:1）配制，于2-8°C冷藏保存，避光，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称
分子式C12H16N4O3
分子量264.28 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1959年
含氮原子数4

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  2. 发明人何建平，王建平，周伟. "Method for the Synthesis of 903A9K181P 7248-21-7 Iprazochrome [INN] Iprazochrome Hydrazinecarboxamide, 2-(3-hydroxy-1-(1-methylethyl)-6-oxo-1,2,3,6-tetrahydro-5H-indol-5-ylidene)- Hydrazinecarboxamide, 2-(1,2,3,6-tetrahydro-3-hydroxy-1-(1-methylethyl)-6-oxo-5H-indol-5-ylidene)- (9CI) 3-Hydroxy-1-isopropyl-5,6-indolinedione 5-semicarbazone 5,6-Indolinedione, 3-hydroxy-1-isopropyl-, 5-semicarbazone (8CI) 2-(1,2,3,6-Tetrahydro-3-hydroxy-1-(1-methylethyl)-6-oxo-5H-indol-5-ylidene)hydrazinecarboxamide Divascan 5,6-Indolinedione, 3-hydroxy-1-isopropyl-, 5-semicarbazone Iprazochromum [INN-Latin] Iprazocromo [INN-Spanish] ISI 1-Isopropyl-3-hydroxy-5-semicarbazone-6-oxo-2,3,5,6-tetrahydroindole Isopropylnoradenochrome monosemicarbazone Isopropylnoradrenochrome monosemicarbazone Novochrome NSC 10065 Iprazochromum Iprazocromo UNII-903A9K181P" [P]. 中国发明专利, 专利号 CN 113519912 B, 授权公告日 2023-01-05.
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参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". J. Nat. Prod., 2022, 1319, (10), 5303-5321.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". J. Sep. Sci., 2015, 629, (4), 3578-3607.
  3. Hughes D, Roberts J, Thomas A. "Identification and Structural Characterization of a Novel Degradation Product of 903A9K181P 7248-21-7 Iprazochrome [INN] Iprazochrome Hydrazinecarboxamide, 2-(3-hydroxy-1-(1-methylethyl)-6-oxo-1,2,3,6-tetrahydro-5H-indol-5-ylidene)- Hydrazinecarboxamide, 2-(1,2,3,6-tetrahydro-3-hydroxy-1-(1-methylethyl)-6-oxo-5H-indol-5-ylidene)- (9CI) 3-Hydroxy-1-isopropyl-5,6-indolinedione 5-semicarbazone 5,6-Indolinedione, 3-hydroxy-1-isopropyl-, 5-semicarbazone (8CI) 2-(1,2,3,6-Tetrahydro-3-hydroxy-1-(1-methylethyl)-6-oxo-5H-indol-5-ylidene)hydrazinecarboxamide Divascan 5,6-Indolinedione, 3-hydroxy-1-isopropyl-, 5-semicarbazone Iprazochromum [INN-Latin] Iprazocromo [INN-Spanish] ISI 1-Isopropyl-3-hydroxy-5-semicarbazone-6-oxo-2,3,5,6-tetrahydroindole Isopropylnoradenochrome monosemicarbazone Isopropylnoradrenochrome monosemicarbazone Novochrome NSC 10065 Iprazochromum Iprazocromo UNII-903A9K181P Using HRMS and NMR". Talanta, 2022, 344, (4), 9445-9461.

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