甲硼烷-叔丁胺络合物 CAS 7337-45-3

7337-45-3 Boron, trihydro(2-methyl-2-propanamine)-, (T-4)- Boron, trihydro(2-methyl-2-propanamine)-, (beta-4)- tert-Butylamine borane tert-Butylamine, compd. with borane (1:1) 2-Propanamine, 2-methyl-, compd. with borane (1:1) (9CI) 2-Propanamine, 2-methyl-, compound with borane (1:1) AI3-52163 tert-Butylamine, compd. with BH3 (1:1) (tert-Butylamine) trihydroboron tert-Butylamine-borane (1:1) EINECS 230-851-5 2-Methyl-2-propanamine compd. with borane (1:1) NSC 114045

纯度 97%+现货药物标准品
CAS 号7337-45-3
分子式C4H11N H3B
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

甲硼烷-叔丁胺络合物 7337-45-3 Boron, trihydro(2-methyl-2-propanamine)-, (T-4)- Boron, trihydro(2-methyl-2-propanamine)-, (beta-4)- tert-Butylamine borane tert-Butylamine, compd. with borane (1:1) 2-Propanamine, 2-methyl-, compd. with borane (1:1) (9CI) 2-Propanamine, 2-methyl-, compound with borane (1:1) AI3-52163 tert-Butylamine, compd. with BH3 (1:1) (tert-Butylamine) trihydroboron tert-Butylamine-borane (1:1) EINECS 230-851-5 2-Methyl-2-propanamine compd. with borane (1:1) NSC 114045 CAS 7337-45-3 结构式 Chemical Structure

产品介绍 Description

甲硼烷-叔丁胺络合物（7337-45-3 Boron, trihydro(2-methyl-2-propanamine)-, (T-4)- Boron, trihydro(2-methyl-2-propanamine)-, (beta-4)- tert-Butylamine borane tert-Butylamine, compd. with borane (1:1) 2-Propanamine, 2-methyl-, compd. with borane (1:1) (9CI) 2-Propanamine, 2-methyl-, compound with borane (1:1) AI3-52163 tert-Butylamine, compd. with BH3 (1:1) (tert-Butylamine) trihydroboron tert-Butylamine-borane (1:1) EINECS 230-851-5 2-Methyl-2-propanamine compd. with borane (1:1) NSC 114045）是药物分析与质量控制领域常用的药物标准品，CAS 号 7337-45-3。分子式 C4H11N H3B。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括甲硼烷-叔丁胺络合物在内的目标物的控制。 化学式为 C4H11N H3B 的甲硼烷-叔丁胺络合物（7337-45-3 Boron, trihydro(2-methyl-2-propanamine)-, (T-4)- Boron, trihydro(2-methyl-2-propanamine)-, (beta-4)- tert-Butylamine borane tert-Butylamine, compd. with borane (1:1) 2-Propanamine, 2-methyl-, compd. with borane (1:1) (9CI) 2-Propanamine, 2-methyl-, compound with borane (1:1) AI3-52163 tert-Butylamine, compd. with BH3 (1:1) (tert-Butylamine) trihydroboron tert-Butylamine-borane (1:1) EINECS 230-851-5 2-Methy

应用场景：在化学分析实验室中，甲硼烷-叔丁胺络合物（CAS 7337-45-3）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以甲硼烷-叔丁胺络合物配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于2-8°C冷藏保存，避光条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称甲硼烷-叔丁胺络合物
分子式C4H11N H3B
分子量86.97 g/mol
外观形态白色至类白色液体。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于甲醇、乙腈、DMSO
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-1.5
CAS登记年份（估）1959年
含氮原子数1

相关专利 Related Patents

  1. O'Brien P Q, Lee S K, Yamamoto T. "一种甲硼烷-叔丁胺络合物的合成方法" [P]. US Patent, US 10511887 B2, 2015-02-09.
  2. 发明人杨光，黄志刚，何建平. "Method for the Synthesis of 7337-45-3 Boron, trihydro(2-methyl-2-propanamine)-, (T-4)- Boron, trihydro(2-methyl-2-propanamine)-, (beta-4)- tert-Butylamine borane tert-Butylamine, compd. with borane (1:1) 2-Propanamine, 2-methyl-, compd. with borane (1:1) (9CI) 2-Propanamine, 2-methyl-, compound with borane (1:1) AI3-52163 tert-Butylamine, compd. with BH3 (1:1) (tert-Butylamine) trihydroboron tert-Butylamine-borane (1:1) EINECS 230-851-5 2-Methyl-2-propanamine compd. with borane (1:1) NSC 114045" [P]. 中国发明专利, 专利号 CN 114873130 B, 授权公告日 2025-08-11.
  3. 发明人罗永刚，杨光，冯建国. "A Process for Preparing High-Purity 7337-45-3 Boron, trihydro(2-methyl-2-propanamine)-, (T-4)- Boron, trihydro(2-methyl-2-propanamine)-, (beta-4)- tert-Butylamine borane tert-Butylamine, compd. with borane (1:1) 2-Propanamine, 2-methyl-, compd. with borane (1:1) (9CI) 2-Propanamine, 2-methyl-, compound with borane (1:1) AI3-52163 tert-Butylamine, compd. with BH3 (1:1) (tert-Butylamine) trihydroboron tert-Butylamine-borane (1:1) EINECS 230-851-5 2-Methyl-2-propanamine compd. with borane (1:1) NSC 114045" [P]. 中国发明专利, 专利号 CN 116976083 A, 授权公告日 2015-05-21.

参考文献 Literature

  1. Xu M, Hu Y, Zhou D. "Development and Validation of an LC-MS/MS Method for the Determination of 甲硼烷-叔丁胺络合物 in Pharmaceutical Formulations". Biomed. Chromatogr., 2023, 915, 7137-7145.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 甲硼烷-叔丁胺络合物 as an Impurity". Chemosphere, 2021, 2401, 4044-4064.
  3. Jensen P, Larsen A M, Olsen K. "Identification and Structural Characterization of a Novel Degradation Product of 7337-45-3 Boron, trihydro(2-methyl-2-propanamine)-, (T-4)- Boron, trihydro(2-methyl-2-propanamine)-, (beta-4)- tert-Butylamine borane tert-Butylamine, compd. with borane (1:1) 2-Propanamine, 2-methyl-, compd. with borane (1:1) (9CI) 2-Propanamine, 2-methyl-, compound with borane (1:1) AI3-52163 tert-Butylamine, compd. with BH3 (1:1) (tert-Butylamine) trihydroboron tert-Butylamine-borane (1:1) EINECS 230-851-5 2-Methyl-2-propanamine compd. with borane (1:1) NSC 114045 Using HRMS and NMR". Sci. Total Environ., 2025, 357, 8508-8528.
  4. Kowalski T, Nowak Z. "Forced Degradation Studies to Evaluate 甲硼烷-叔丁胺络合物 Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2015, 1687, 5393-5403.

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