1,4-双(二苯基膦)丁烷 CAS 7688-25-7

1,4-Bis(diphenylphosphino)butane 7688-25-7 1,4-BIS(DIPHENYLPHOSPHINE)BUTANE;1,4-BIS(DIPHENYLPHOSPHINO)BUTANE;1,4-BUTANEDIYLBIS[DIPHENYLPHOSPHINE];1,4-BUTYLENEBIS(DIPHENYLPHOSPHINE);DPPB;TETRAMETHYLENEBIS(DIPHENYLPHOSPHINE);[4-(DIPHENYLPHOSPHANYL)BUTYL]DIPHENYLPHOSPHANE GC10108

纯度 97%+现货药物标准品
CAS 号7688-25-7
分子式C28H52P2
分子量450.66 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1,4-双(二苯基膦)丁烷 1,4-Bis(diphenylphosphino)butane 7688-25-7 1,4-BIS(DIPHENYLPHOSPHINE)BUTANE;1,4-BIS(DIPHENYLPHOSPHINO)BUTANE;1,4-BUTANEDIYLBIS[DIPHENYLPHOSPHINE];1,4-BUTYLENEBIS(DIPHENYLPHOSPHINE);DPPB;TETRAMETHYLENEBIS(DIPHENYLPHOSPHINE);[4-(DIPHENYLPHOSPHANYL)BUTYL]DIPHENYLPHOSPHANE GC10108 CAS 7688-25-7 结构式 Chemical Structure

产品介绍 Description

CAS 7688-25-7 对应的1,4-双(二苯基膦)丁烷（1,4-Bis(diphenylphosphino)butane 7688-25-7 1,4-BIS(DIPHENYLPHOSPHINE)BUTANE;1,4-BIS(DIPHENYLPHOSPHINO)BUTANE;1,4-BUTANEDIYLBIS[DIPHENYLPHOSPHINE];1,4-BUTYLENEBIS(DIPHENYLPHOSPHINE);DPPB;TETRAMETHYLENEBIS(DIPHENYLPHOSPHINE);[4-(DIPHENYLPHOSPHANYL)BUTYL]DIPHENYLPHOSPHANE GC10108）为 CATO 佳途药物标准品产品线成员。分子式 C28H52P2，分子量 450.66。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

在质量保证方面，1,4-双(二苯基膦)丁烷的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 化学式为 C28H52P2 的1,4-双(二苯基膦)丁烷（1,4-Bis(diphenylphosphino)butane 7688-25-7 1,4-BIS(DIPHENYLPHOSPHINE)BUTANE;1,4-BIS(DIPHENYLPHOSPHINO)BUTANE;1,4-BUTANEDIYLBISDIPHENYLPHOSPHINE;1,4-BUTYLENEBIS(DIPHENYLPHOSPHINE);DPPB;TETRAMETHYLENEBIS(DIPHENYLPHOSPHINE);4-(DIPHENYLPHOSPHANYL)BUTYLDIPHENYLPHOSPHANE GC10108），其CAS登记号是 7688-25-7，分子量为 450.66 g/mo

应用场景：针对化学分析用途，1,4-双(二苯基膦)丁烷（1,4-Bis(diphenylphosphino)butane 7688-25-7 1,4-BIS(DIPHENYLPHOSPHINE)BUTANE;1,4-BIS(DIPHENYLPHOSPHINO)BUTANE;1,4-BUTANEDIYLBIS DIPHENYLPHOSPHINE ;1,4-BUTYLENEBIS(DIPHENYLPHOSPHINE);DPPB;TETRAMETHYLENEBIS(DIPHENYLPHOSPHINE); 4-(DIPHENYLPHOSPHANYL)BUTYL DIPHENYLPHOSPHANE GC10108

理化性质 Physical & Chemical Properties

中文名称1,4-双(二苯基膦)丁烷
分子式C28H52P2
分子量450.66 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1959年

相关专利 Related Patents

  1. 发明人郭海燕，胡光，徐明华. "一种1,4-双(二苯基膦)丁烷的合成方法" [P]. 中国发明专利, 专利号 CN 109941284 A, 授权公告日 2020-11-08.
  2. 发明人马晓峰，孙丽萍，罗永刚. "Method for the Synthesis of 1,4-Bis(diphenylphosphino)butane 7688-25-7 1,4-BIS(DIPHENYLPHOSPHINE)BUTANE;1,4-BIS(DIPHENYLPHOSPHINO)BUTANE;1,4-BUTANEDIYLBIS[DIPHENYLPHOSPHINE];1,4-BUTYLENEBIS(DIPHENYLPHOSPHINE);DPPB;TETRAMETHYLENEBIS(DIPHENYLPHOSPHINE);[4-(DIPHENYLPHOSPHANYL)BUTYL]DIPHENYLPHOSPHANE GC10108" [P]. 中国发明专利, 专利号 CN 116877894 A, 授权公告日 2020-03-09.
  3. 发明人刘建华，黄志刚，唐晓军. "A Process for Preparing High-Purity 1,4-Bis(diphenylphosphino)butane 7688-25-7 1,4-BIS(DIPHENYLPHOSPHINE)BUTANE;1,4-BIS(DIPHENYLPHOSPHINO)BUTANE;1,4-BUTANEDIYLBIS[DIPHENYLPHOSPHINE];1,4-BUTYLENEBIS(DIPHENYLPHOSPHINE);DPPB;TETRAMETHYLENEBIS(DIPHENYLPHOSPHINE);[4-(DIPHENYLPHOSPHANYL)BUTYL]DIPHENYLPHOSPHANE GC10108" [P]. 中国发明专利, 专利号 CN 111150661 A, 授权公告日 2020-10-18.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of 1,4-双(二苯基膦)丁烷 in Pharmaceutical Formulations". J. Sep. Sci., 2019, 1175, 8220-8224.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1,4-双(二苯基膦)丁烷 as an Impurity". J. Agric. Food Chem., 2017, 678, 1562-1574.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of 1,4-Bis(diphenylphosphino)butane 7688-25-7 1,4-BIS(DIPHENYLPHOSPHINE)BUTANE;1,4-BIS(DIPHENYLPHOSPHINO)BUTANE;1,4-BUTANEDIYLBIS[DIPHENYLPHOSPHINE];1,4-BUTYLENEBIS(DIPHENYLPHOSPHINE);DPPB;TETRAMETHYLENEBIS(DIPHENYLPHOSPHINE);[4-(DIPHENYLPHOSPHANYL)BUTYL]DIPHENYLPHOSPHANE GC10108 Using HRMS and NMR". Sci. Total Environ., 2010, 1970, 8651-8669.
  4. Smith J A, Johnson M B. "Forced Degradation Studies to Evaluate 1,4-双(二苯基膦)丁烷 Profile in Drug Substances According to ICH Guidelines". Molecules, 2021, 1722, (5), 2367-2383.

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