二氯二苯基硅烷 CAS 80-10-4

08811ZE689 80-10-4 Dichlorodiphenylsilane Dichloro(diphenyl)silane Silane, dichlorodiphenyl- Benzene, 1,1'-(dichlorosilylene)bis- 4-16-00-01526 (Beilstein Handbook Reference) AI3-51461 BRN 0609882 Dichlor-difenylsilan [Czech] Diphenyl dichlorosilane Diphenylsilicon dichloride Diphenylsilyl dichloride EINECS 201-251-0 HSDB 316 NSC 77110 TSL 8062 Dichlor-difenylsilan UNII-08811ZE689 EC 201-251-0 Diphenyldichlorosilane Diphenyldichlorosilane [UN1769] [Corrosive] UN1769

纯度 97%+现货药物标准品
CAS 号80-10-4
分子式C12H22Cl2Si
分子量265.29 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

二氯二苯基硅烷 08811ZE689 80-10-4 Dichlorodiphenylsilane Dichloro(diphenyl)silane Silane, dichlorodiphenyl- Benzene, 1,1'-(dichlorosilylene)bis- 4-16-00-01526 (Beilstein Handbook Reference) AI3-51461 BRN 0609882 Dichlor-difenylsilan [Czech] Diphenyl dichlorosilane Diphenylsilicon dichloride Diphenylsilyl dichloride EINECS 201-251-0 HSDB 316 NSC 77110 TSL 8062 Dichlor-difenylsilan UNII-08811ZE689 EC 201-251-0 Diphenyldichlorosilane Diphenyldichlorosilane [UN1769] [Corrosive] UN1769 CAS 80-10-4 结构式 Chemical Structure

产品介绍 Description

二氯二苯基硅烷（08811ZE689 80-10-4 Dichlorodiphenylsilane Dichloro(diphenyl)silane Silane, dichlorodiphenyl- Benzene, 1,1'-(dichlorosilylene)bis- 4-16-00-01526 (Beilstein Handbook Reference) AI3-51461 BRN 0609882 Dichlor-difenylsilan [Czech] Diphenyl dichlorosilane Diphenylsilicon dichloride Diphenylsilyl dichloride EINECS 201-251-0 HSDB 316 NSC 77110 TSL 8062 Dichlor-difenylsilan UNII-08811ZE689 EC 201-251-0 Diphenyldichlorosilane Diphenyldichlorosilane [UN1769] [Corrosive] UN1769，CAS 号 80-10-4）是 CATO 佳途自主生产的药物标准品，分子式 C12H22Cl2Si，分子量 265.29。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的定量分析，可作为外标法校准标准品或系统适用性测试参考物质使用。 化学式为 C12H22Cl2Si 的二氯二苯基硅烷（08811ZE689 80-10-4 Dichlorodiphenylsilane Dichloro(diphenyl)silane Silane, dichlorodiphenyl- Benzene, 1,1'-(dichlorosilylene)bis- 4-16-00-01526 (Beilstein Handbook Reference) AI3-51461 BRN 0609882 Dichlor-difenylsilan Czech Diphenyl dichlorosilane Diphenylsilicon dichloride Diphenylsilyl dichloride EINECS 201-251-0 HSDB 316 NSC 77110 TSL 8062 Dichlor-difenylsilan UNII-08811ZE689 EC 201-251

应用场景：针对化学分析用途，二氯二苯基硅烷（08811ZE689 80-10-4 Dichlorodiphenylsilane Dichloro(diphenyl)silane Silane, dichlorodiphenyl- Benzene, 1,1'-(dichlorosilylene)bis- 4-16-00-01526 (Beilstein Handbook Reference) AI3-51461 BRN 0609882 Dichlor-difenylsilan Czech Diphenyl dichlorosilane Diphenylsilicon dichloride Diphen

理化性质 Physical & Chemical Properties

中文名称二氯二苯基硅烷
分子式C12H22Cl2Si
分子量265.29 g/mol
外观形态白色至类白色低熔点固体。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，密闭保存防止挥发
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1957年
卤素含量Cl取代

相关专利 Related Patents

  1. 发明人刘建华，张德明，钱学锋. "一种二氯二苯基硅烷的合成方法" [P]. 中国发明专利, 专利号 CN 108727139 A, 授权公告日 2020-06-21.
  2. Brown S R, Klinger H, Park J H. "Method for the Synthesis of 08811ZE689 80-10-4 Dichlorodiphenylsilane Dichloro(diphenyl)silane Silane, dichlorodiphenyl- Benzene, 1,1'-(dichlorosilylene)bis- 4-16-00-01526 (Beilstein Handbook Reference) AI3-51461 BRN 0609882 Dichlor-difenylsilan [Czech] Diphenyl dichlorosilane Diphenylsilicon dichloride Diphenylsilyl dichloride EINECS 201-251-0 HSDB 316 NSC 77110 TSL 8062 Dichlor-difenylsilan UNII-08811ZE689 EC 201-251-0 Diphenyldichlorosilane Diphenyldichlorosilane [UN1769] [Corrosive] UN1769" [P]. US Patent, US 10822094 B2, 2022-05-01.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of 二氯二苯基硅烷 in Pharmaceutical Formulations". Chromatographia, 2021, 2025, (8), 8168-8192.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 二氯二苯基硅烷 as an Impurity". J. Chromatogr. A, 2025, 238, 2693-2701.
  3. Kim S H, Park J Y. "Identification and Structural Characterization of a Novel Degradation Product of 08811ZE689 80-10-4 Dichlorodiphenylsilane Dichloro(diphenyl)silane Silane, dichlorodiphenyl- Benzene, 1,1'-(dichlorosilylene)bis- 4-16-00-01526 (Beilstein Handbook Reference) AI3-51461 BRN 0609882 Dichlor-difenylsilan [Czech] Diphenyl dichlorosilane Diphenylsilicon dichloride Diphenylsilyl dichloride EINECS 201-251-0 HSDB 316 NSC 77110 TSL 8062 Dichlor-difenylsilan UNII-08811ZE689 EC 201-251-0 Diphenyldichlorosilane Diphenyldichlorosilane [UN1769] [Corrosive] UN1769 Using HRMS and NMR". Talanta, 2020, 1886, 5358-5372.
  4. Kim S H, Park J Y. "Forced Degradation Studies to Evaluate 二氯二苯基硅烷 Profile in Drug Substances According to ICH Guidelines". Environ. Sci. Technol., 2022, 130, (5), 9377-9383.

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