Aridanin CAS 81053-26-1

(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 81053-26-1 Aridanin Olean-12-en-28-oic acid, 3-[[2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl]oxy]-, (3.beta.)-

纯度 97%+现货药物标准品
CAS 号81053-26-1
分子式C38H61NO8
分子量659.89 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Aridanin (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 81053-26-1 Aridanin Olean-12-en-28-oic acid, 3-[[2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl]oxy]-, (3.beta.)- CAS 81053-26-1 结构式 Chemical Structure

产品介绍 Description

CAS 81053-26-1 对应的Aridanin（(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 81053-26-1 Aridanin Olean-12-en-28-oic acid, 3-[[2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl]oxy]-, (3.beta.)-）为 CATO 佳途药物标准品产品线成员。分子式 C38H61NO8，分子量 659.89。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括Aridanin在内的目标物的控制。 Aridanin（(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yloxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 81053-26-1 Aridanin Olean-12-en-28-oic acid, 3-2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyloxy-, (3.beta.)-），CAS注册编号 81053-26-1，化学分子式为 C38H61NO8，分子量 659.89 g/mol。 Aridanin（分子式 C38H61NO8）的化学结构中包含含氮杂环结构，酰

应用场景：Aridanin（(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10- (2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 81053-26-1 Aridanin Olean-12-en-28-oic acid, 3- 2-(acetylam

理化性质 Physical & Chemical Properties

中文名称Aridanin
分子式C38H61NO8
分子量659.89 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）9.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1980年
含氮原子数1

相关专利 Related Patents

  1. 发明人罗永刚，李文辉，朱建伟. "一种Aridanin的合成方法" [P]. 中国发明专利, 专利号 CN 110788279 B, 授权公告日 2023-11-07.
  2. Kumar R, Johnson M A, Park J H. "Method for the Synthesis of (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 81053-26-1 Aridanin Olean-12-en-28-oic acid, 3-[[2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl]oxy]-, (3.beta.)-" [P]. US Patent, US 11793249 B2, 2015-04-08.
  3. 发明人高志强，陈志强，王建平. "A Process for Preparing High-Purity (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 81053-26-1 Aridanin Olean-12-en-28-oic acid, 3-[[2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl]oxy]-, (3.beta.)-" [P]. 中国发明专利, 专利号 CN 110162789 B, 授权公告日 2017-03-01.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of Aridanin in Pharmaceutical Formulations". J. Nat. Prod., 2016, 1116, (4), 3437-3448.
  2. Xu M, Hu Y, Zhou D. "A Stability-Indicating HPLC Method for the Separation and Quantification of Aridanin as an Impurity". Chromatographia, 2021, 2284, 6457-6482.
  3. Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 81053-26-1 Aridanin Olean-12-en-28-oic acid, 3-[[2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl]oxy]-, (3.beta.)- Using HRMS and NMR". Biomed. Chromatogr., 2021, 1294, (12), 6777-6803.
  4. Brown R C, Davis S M. "Forced Degradation Studies to Evaluate Aridanin Profile in Drug Substances According to ICH Guidelines". Chemosphere, 2023, 891, 9344-9348.

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